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Quantum pharmacology /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Richards, W. G. (William Graham)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London ; Boston : Butterworths, 1983.
Edición:2nd ed.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Front Cover; Quantum Pharmacology; Copyright Page; Preface to second edition; Preface to first edition; Table of Contents; Introduction; Part I: Molecular pharmacology; Chapter 1. Small molecules in biology; Action Potentials; The classification of nerves; Neuron structure and junctions; Nerve transmitters; Synaptic actions of neuro-transmitters; Receptors; Summary; Further reading; Chapter 2. Quantitative pharmacology; Pharmacological measurements; Responses; Dose-response curves; Direct binding studies; Theories of drug action; Quantitative receptor theory; Some complications; Summary.
  • Physiological and pathological effectsHistamine release; Pharmacological testing; Agonists; H1 Antagonists; H2 Antagonists; Summary; Further reading; Chapter 6. Central nervous system I. Monoamines and acetylcholine; Chemical transmitters; Catecholamines; Histamine; Acetylcholine; Central nervous system drugs; Antipsychotics; Antidepressants; Psychomotor stimulants; Hallucinogens; Further reading; Chapter 7. Central nervous system II. Amino acids and peptides; Amino acids; Anti-anxiety drugs; Anti-epileptic drugs; Peptides; Analgesics; Summary; Further reading; Chapter 8. Anaesthetics.
  • General anaestheticsTheories of general anaesthesia; Local anaesthetics; Summary; Further reading; Chapter 9. Chemotherapy; Sulphonamides; Antibiotics; Antimalarials; Antiviral agents; Cancer chemotherapy; Summary; Further reading; Chapter 10. Other areas; Kinins; Prostaglandins; Anti-inflammatory drugs; Hormones; Vitamins; Summary; Further reading; Part II: Molecular quantum mechanics; Chapter 11. Wave functions and orbitals; Wave functions; Orbitals; Spin-orbitals and antisymmetry; Molecular orbitals; Secular equations; Matrix elements; Self-consistent molecular orbitals.
  • Configuration interactionSummary; Further reading; Chapter 12. Approximate wave functions; Ab initio methods; Correlation energy; Semi-empirical calculations; Neglect of differential overlap; The use of localized orbitals; Use of an undefined hamiltonian operator; Computer programs for molecular orbital calculations; Summary; Further reading; Chapter 13. Calculated molecular properties; Energies; Molecular geometry; Conformation; Conformational free energies; Ionization potentials and electron affinities; Charge distribution; Mulliken population analysis; Molecular potential fields.