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A pharmacology primer : theory, applications, and methods /

This guide has been designed especially for scientists trained in molecular biology and related fields who now need to know more about the basic theories, principles and practical applications of pharmacology.

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Kenakin, Terrence P.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam ; Boston : Academic Press/Elsevier, �2009.
Edición:3rd ed.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • What is pharmacology?
  • How different tissues process drug response
  • Drug-receptor theory
  • Pharmacological assay formats : binding
  • Agonists : the measurement of affinity and efficacy in functional assays
  • Orthosteric drug antagonism
  • Allosteric drug antagonism
  • The process of drug discovery
  • Pharmacokinetics
  • Target- and system-based strategies for drug discovery
  • "Hit" to drug : lead optimization
  • Statistics and experimental design
  • Selected pharmacological methods
  • Exercises in pharmacodynamics and pharmacokinetics.