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GABAB receptor pharmacology : a tribute to Norman Bowery /
This monograph was assembled to honor Professor Norman Bowery and his work on the 30th anniversary of his discovery of the GABAB receptor. In the present volume leading neuroscientists from academia and industry provide a perspective of current research, both basic and translational in the discovery...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
San Diego, Calif. :
Elsevier,
2009.
|
| Colección: | Advances in pharmacology (San Diego, Calif.) ;
v. 58. |
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Historical perspective and emergence of the GABAB receptor
- Chemistry and pharmacology of GABAB receptor ligands
- Heterodimerization of the GABAB receptor: implications for GPCR signaling and drug discovery
- Mechanisms of GABAB receptor exocytosis, endocytosis, and degradation
- Functional modulation of GABAB receptors by protein kinases and receptor trafficking
- GABAB receptor coupling to g-proteins and ion channels
- GABAB receptor-mediated modulation of metabotropic glutamate signaling and synaptic plasticity in central neurons
- GABA transporter GATI: a crucial determinant of GABAB receptor activation in cortical circuits?
- Roles of GABAB receptors in cortical network activity
- GABAB receptors: physiological functions and mechanisms of diversity
- Role of GABAB receptors in autonomic control of systemic blood pressure
- GABAB receptor agonism as a novel therapeutic modality in the treatment of gastroesophageal reflux disease
- GABAB receptors in reward processes
- GABAB receptors in addiction and its treatment
- GABAB-GIRK2-mediated signaling in Down syndrome
- GABAB receptors and depression: current status
- GABA-B receptors in drosophila.