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The Flaviviruses : Detection, Diagnosis and Vaccine Development /

Over 50% of known flaviviruses have been associated with human disease. The Flavivirus genus constitutes some of the most serious human pathogens including Japanese encephalitis, dengue and yellow fever. Flaviviruses are known for their complex life cycles and epidemic spread, and are considered a g...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Chambers, Thomas J. (Editor ), Monath, Thomas P. (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam, Netherlands ; New York, NY : Elsevier Academic Press, 2003.
Colección:Advances in virus research ; v. 61.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Cover; Contents; Part 1: DIAGNOSIS AND SURVEILLANCE; Chapter 1. Serodiagnosis of Flaviviral Infections and Vaccinations in Humans; I. Introduction; II. Serodiagnostic Tests; III. Specimens; IV. Variations in Antibody Responses and Antibody Kinetics; V. Flavivirus Cross-Reactivity; VI. Properties of Serologic Tests; VII. Commercial Reagents, Test Kits, and Services; VIII. Diagnostic Strategies; References; Chapter 2. Molecular Amplification Assays for the Detection of Flaviviruses; I. Introduction.; II. Overview of Molecular Amplification Technologies; III. RT-PCR-Based Assays for Flaviviruses
  • IV. NASBA Assays for FlavivirusesV. Conclusion; References; Part 2: VIRUS EPIDEMIOLOGY, ECOLOGY, AND EMERGENCE; Chapter 3. Japanese Encephalitis; I. History; II. Clinical Description; III. Congenital Infection; IV. Animal Infections; V. Geographic Distribution; VI. Geographic Variation in Virus Strains; VII. Recent Changes in Geographic Range; VIII. Incidence and Prevalence; IX. Risk Factors; X. Ecological Factors in Disease Transmission; XI. Future Directions; References; Chapter 4. Epidemiology of St. Louis Encephalitis Virus; I. History; II. Clinical Description and Diagnosis
  • III. Geographical Distribution and Genetic VariationIV. Incidence and Prevalence.; V. Risk Factors; VI. Transmission Cycles; VII. Surveillance and Control; VIII. Impact of West Nile Virus Introduction; References; Chapter 5. West NileVirus: Epidemiology and Ecology in North America; I. Introduction; II. History; III. Clinical Description; IV. Geographic Distribution; V. Molecular Epidemiology; VI. Epidemiology and Epizootiology; VII. Ecology; VIII. Future Directions; References; Chapter 6. Dengue Epidemiology:Virus Epidemiology, Ecology,and Emergence; I. Introduction; II. History
  • III. Clinical DescriptionIV. Pathophysiology of Dengue Hemorrhagic Fever; V. Geographical Distribution; VI. Ecology of Dengue from a Biological Perspective; VII. Control of DF/DHF by Management of the Mosquito Vector; VIII. Future Prospects; IX. Conclusions; References; Chapter 7. Epidemiology and Ecology of Yellow Fever Virus; I. History; II. Classification; III. Ecology of Yellow Fever Virus; IV. Epidemiology of Yellow Fever Virus; V. Molecular Biology of Yellow Fever Virus; VI. Reemergence of Yellow Fever as a Major Public Health Problem; References; Chapter 8. Tick-Borne Flaviviruses
  • I. IntroductionII. Tick-Borne Encephalitis Virus, a Major Human Pathogen; III. Other Encephalitic Tick-Transmitted Flaviviruses; IV. Non-Encephalitic Mammalian Tick-Borne Flaviviruses; V. ''Hemorrhagic'' Tick-Borne Viruses; VI. Seabird Tick-Transmitted Viruses; VII. Control of Tick-Borne Encephalitis: Prospects for Live Attenuated Tick-Borne Encephalitis Virus Vaccines; VIII. Conclusions; References; Chapter 9. Epidemiology of Other Arthropod-Borne Flaviviruses Infecting Humans; I. Introduction; II. Other Flaviviruses of Africa; III. Other Flaviviruses of Europe