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Advances in virus research. Volume 55 /

Virology is the branch of microbiology that deals with viruses and viral infections. The overall goal of virus research is understand the action of various viruses and develop vaccines or techniques that are effective at preventing or treating the diseases caused by them. Viruses that affect humans...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Maramorsch, Karl, Murphy, Frederick A., Shatkin, Aaron J.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York : Academic Press, 2000.
Colección:Advances in virus research ; v. 55
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Front Cover; Advances in Virus Research; Copyright Page; Contents; Chapter 1. DNA Vaccines for Viral Infections: Basic Studies and Applications; I. Introduction; II. Plasmid Vectors and Delivery; III. Mechanistic Basis for DNA-Raised Immune Responses; IV. Immune Responses Raised by DNA; V. Increasing the Efficiency of DNA-Based Immunizations; VI. Applications; VII. Safety Issues; VIII. Future Promise; References; Chapter 2. SV40 Large T Antigen Functions in DNA Replication and Transformation; I. Introduction; II. Structural Properties; III. Structure of Origin
  • IV. Oligomerization and DNA BindingV. Helicase Activity and Unwinding of DNA; VI. Replication of SV40 DNA; VII. Regulation of T Antigen Activity by Phosphorylation; VIII. Multifunctionality of T Antigen Domains; IX. Transformation and Immortalization of Cells; X. Role of T Antigen in Transcription; XI. Chromosome Rearrangements and Recombination; XII. Nuclear Transport of Cellular Proteins; XIII. Role of T Antigen in Virus Assembly; XIV. Remaining Puzzles and Promising Directions; References; Chapter 3. Viral and Cellular mRNA Capping: Past and Prospects; I. Introduction; II. Discovery
  • III. Caps in Eukaryotic mRNAsIV. Mechanisms of Synthesis; V. Performed Capped 5' End Addition to Cellular and Viral mRNAs; VI. Cap Functions; VII. Conclusion; References; Chapter 4. Mechanism of Genome Transcription in Segmented dsRNA Viruses; I. Introduction; II. Organization of Transcription Apparatus; III. Mechanisms of mRNA Production; IV. Summary; References; Chapter 5. Structures and Mechanisms in Flavivirus Fusion; I. Introduction; II. Flaviviruses; III. General Features of Viral Fusion Proteins; IV. Flavivirus Entry, Assembly, and Release; V. Recombinant Subviral Particles
  • VI. Fusion Characteristics of FlavivirusesVII. Structural Basis for Flavivirus Fusion; VIII. Conclusion; References; Chapter 6. Avsunviroidae Family: Viroids Containing Hammerhead Ribozymes; I. Introduction; II. History; III. Molecular Structure and Taxonomy; IV. Biological Properties; V. Replication Cycle; VI. Pathogenesis; VII. Genetics; VIII. Origin and Evolution of Hammerhead Viroids.; IX. Concluding Remarks; References; Chapter 7. Virus Resistance Mediated by Ribosome Inactivating Proteins; I. Introduction; II. General Properties; III. Enzymatic Activity
  • IV. Protein Structure and Function of PAP and Other RIPs. .V. Biological Activity; VI. Conclusion; References; Chapter 8. Groundnut Rosette Disease Virus Complex: Biology and Molecular Biology; I. Introduction; II. Biology of Groundnut Rosette Disease Complex; III. Genome Organization and Expression of Causal Agents; IV. Functions of Proteins and RNA Elements: Functional Interactions between Agents Causing Disease; V. Disease Control: Cultural Measures and Resistance; VI. Similar Plant Virus Complexes; References; Special Section: Virus Vectors for Gene Therapy