Advances in clinical chemistry. Volume 45 /

Volume forty-five of the Advances in Clinical Chemistry series contains review articles of wide interest to clinical laboratory scientists and diagnostic adventurers. Articles in this volume cover such topics as Inhibins as Diagnostic Markers in Human Reproduction; uPA and PAI-1 in Breast Cancer: Re...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Makowski, Gregory S. (Gregory Stephen)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam ; Boston : Academic Press, 2008.
Colección:Advances in Clinical Chemistry.
Temas:
Clinical chemistry.
Clinical biochemistry.
Chemistry, Clinical
Chimie clinique.
Biochimie clinique.
Clinical biochemistry
Clinical chemistry
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Front Cover; Advances in Clinical Chemistry; Copyright Page; Contents; Contributors; Preface; Chapter 1: Inhibins as Diagnostic Markers in Human Reproduction; 1. Abstract; 2. History and Background; 3.2. Inhibin During the Menstrual Cycle; 3.3. Control of Inhibin B by FSH in Gnrh-Deficient Women; 3.4. Inhibins and Activin A in Ovulation Induction; 3.5. Premature Ovarian Failure; 3.6. Inhibin and Activin in Polycystic Ovary Syndrome; 3.7. Reproductive Aging; 4. Pregnancy; 4.1. Inhibin in Abnormal Pregnancy; 4.2. Pre-eclampsia; 4.3. Down's Syndrome; References; 1. Abstract
  • 3. Clinical Relevance of UPA and PAI-1 in Breast Cancer3.2. Predictive Impact of UPA and PAI-1; 1. Abstract; 3.2. High-Content Cellular Imaging; 3.3. Suspension Arrays/Flow Cytometry; 4. Fluorescence Technology; 4.1. Fluorescence-Based Assays; 4.2. Fluorescent Labels; 5. Flow-Cytometry High-Content Profiling Applications; 5.1. Principles of Multiplexing for Suspension Arrays; 5.2. Multiplexed Nucleic Acid Endpoint Assays; 5.3. Multiplexed Protein Endpoint Assays; 5.4. Multiplex Assays of Molecular Assemblies; 5.5. Throughput; 6. Future Directions; Acknowledgments; References; 1. Abstract
  • 2. Introduction3. Rationale for Immune Monitoring; 3.1. Requirements; 3.2. Significance; 4. Selection of Assays for Immune Monitoring; 4.1. Use of Cryopreserved vs. Freshly Harvested Specimens; 4.2. Single-Cell Assays: Tetramers, CFC, ELISPOT; 4.3. Elispot as a Monitoring Assay; 4.4. Attributes of Selected Assays; 5. Profiling of in Immune Biomarkers; 5.1. Multiplexing for Cytokines; 5.2. Genomics and Proteomics; 5.3. Polychromatic Flow Cytometry; 6. The QA/QC Program and Assay Quality; 6.1. QA/QC in Practice; 6.2. Assay Standardization; 6.3. Assay Validation
  • 7. Interpretation of Immune Monitoring Assays7.1. Statistical Analysis; 7.2. Interpretation Discrepancies; 8. Conclusions; Acknowledgment; References; 1. Abstract; 2. Introduction; 3. Meal Composition; 3.1. Carbohydrate; 3.2. Fat; 3.3. Protein; 3.4. Antioxidant; 3.5. Phytochemicals; 3.6. Vitamins; 3.7. Minerals and Trace Elements; 4. Meal Frequency; 5. Meal Size; 6. Appetite; 7. Emotion; 8. Metabolic Acidosis; 9. Glucocorticoids; 10. Monoamine; 11. Stress; 12. Conclusion; References; 1. Abstract; 2. Introduction; 3. Hypothesized Pathogenic Mechanisms of AD
  • 4. Gender Dichotomy in AD: Role of Sex Steroids5. A Gonadotropin Evidence-Based Hypothesis for AD: High Gonadotropin vs Low Estrogen; 6. Conclusion; References; Abbreviations; 1. Abstract; 2. Introduction; 3. Trp-Kynurenine Degradation Pathway; 3.1. Comparison Between IDO and TDO; 3.2. Distribution of the Kynurenine Pathway Enzymes; 4. Biochemistry of IDO; 4.1. Molecular Biology of the Indo Gene; 4.2. Catalytic Properties of IDO; 4.3. Posttranslational Regulation of the IDO Activity; 5. IDO Induction; 5.1. Induction of IDO by IFNS

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