Advances in clinical chemistry /

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Volume thirty-nine in the internationally acclaimed Advances in Clinical Chemistry, contains chapters submitted from leading experts from academia and clinical laboratory science. Authors are from a diverse field of clinical chemistry disciplines and diagnostics ranging from basic biochemical explor...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Makowski, Gregory S.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York : Academic Press, 2005.
Colección:Advances in Clinical Chemistry.
Temas:
Clinical chemistry.
Biochemistry.
Chemistry, Clinical
Biochemistry
Chimie clinique.
Biochimie.
biochemistry.
Clinical chemistry
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Front Cover
  • Advances in Clinical Chemistry
  • Copyright Page
  • Contents
  • Contributors
  • Preface
  • Chapter 1. Clinical and Analytical Review of Ischemia-Modified Albumin Measured by the Albumin Cobalt Binding Test
  • 1. Introduction
  • 2. IMA and the ACB Test
  • 3. Clinical Studies Review
  • 4. Future Needs and Unanswered Questions
  • 5. Summary
  • References
  • Chapter 2. Human Tissue Kallikreins: From Gene Structure to Function and Clinical Applications
  • 1. Introduction.
  • 2. Discovery of the Human Tissue Kallikrein Gene Locus: A Short Historical Perspective
  • 3. Kallikreins in Rodents and Other Species
  • 4. Characterization and Sequence Analysis of the Human Tissue Kallikrein Gene Locus
  • 5. Structural Features of the Human Tissue Kallikrein Genes and Proteins
  • 6. Sequence Variations of Human Kallikrein Genes
  • 7. The Tissue Kallikreins in the Context of Other Serine Proteases in the Human Genome
  • 8. Tissue Expression and Cellular Localization of the Kallikrein Genes
  • 9. Regulation of Kallikrein Activity.
  • 10. Hormonal Regulation of Kallikreins
  • 11. Evolution of Kallikreins
  • 12. Cross-Talk Between Kallikreins: A Possible Novel Enzymatic Cascade Pathway
  • 13. Isoforms and Splice Variants of the Human Kallikreins
  • 14. Kallikreins in Normal Physiology
  • 15. Association of Kallikreins with Human Diseases
  • 16. Kallikreins and Cancer
  • 17. Therapeutic Applications
  • 18. Future Directions
  • References
  • Chapter 3. Cholesterol and Lipids in Depression: Stress, Hypothalamo-Pituitary-Adrenocortical Axis, and Inflammation/Immunity
  • 1. Introduction.
  • 2. The Relationships Between Lipid Profile Levels, Depression, and Suicide Attempts
  • 3. The Interactions Between Stress, Lipid Profiles, Cortisone/HPA Axis, and Inflammation/Immunity
  • 4. Clinical Phenotypes in Depression and Molecular Levels
  • 5. Conclusion
  • References
  • Chapter 4. Advances on Biological Markers in Early Diagnosis of Alzheimer Disease
  • 1. Introduction
  • 2. Biological Aspects of AD Pathogenesis
  • 3. Diagnostic Issues
  • 4. Biological Markers and Early Diagnosis of AD
  • 5. CSF Biomarkers
  • 6. Peripheral Biomarkers.
  • 7. Future Approaches in Preclinical Diagnosis of AD
  • 8. Conclusive Remarks
  • References
  • Chapter 5. Endothelial Microparticles (EMP) as Vascular Disease Markers
  • 1. Introduction
  • 2. Characterization of EMPs
  • 3. Methodology to Detect EMP
  • 4. EMPs in Clinical Disease
  • 5. Perspective
  • References
  • Chapter 6. Proteomics in Clinical Laboratory Diagnosis
  • 1. Introduction to Proteomics
  • 2. Modern Proteomic Technology
  • 3. Proteins, Proteomics, and Patterns
  • 4. Accessing Biological Samples.

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