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Advances in immunology /

Advances in Immunology, a long established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecul...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Alt, Frederick W.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York : Academic Press, 2005.
Colección:Advances in immunology ; 86
Temas:
Acceso en línea:Texto completo
Texto completo

MARC

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245 0 0 |a Advances in immunology /  |c edited by Frederick W. Alt. 
260 |a New York :  |b Academic Press,  |c 2005. 
300 |a 1 online resource (x, 319 pages) :  |b illustrations, diagrams. 
336 |a text  |b txt  |2 rdacontent 
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490 0 |a Advances in immunology ;  |v 86 
504 |a Includes bibliographical references. 
588 0 |a Print version record. 
520 |a Advances in Immunology, a long established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research. 
505 0 |a Cover Page; Title Page; Copyright Page; Contents; Contributors; Chapter 1: A Reappraisal of Humoral Immunity Based on Mechanisms of Antibody-Mediated Protection Against Intracellular Pathogens; 1. Introduction; 2. Intracellular and Extracellular Pathogenic Microbes: How Distinct Are They?; 3. Components of AMI; 4. AMI in the Context of the ""Damage-Response Framework""; 5. Abs as Enhancers of Innate Immunity; 6. Abs as Direct and Indirect Effector Molecules; 7. AMI as a Regulator of the Inflammatory Response; 8. Dose-Response Conundrum 
505 8 |a 9. Ab-Mediated Protection Against Intracellular Pathogens10. Protective Efficacy of an Ab Molecule; 11. Some Emerging Concepts; Acknowledgments; References; Chapter 2: Accessibility Control of V(D)J Recombination; 1. Introduction; 2. V(D)J Recombination: A Mechanistic Perspective; 3. Genomic Architecture of Ig and TCR Loci; 4. Regulation of Antigen Receptor Gene Assembly During Lymphocyte Development; 5. Regulation of V(D)J Recombination: The Accessibility Hypothesis and Beyond; 6. Chromatin Structure and Accessibility Control Mechanisms 
505 8 |a 7. Regulation of Antigen Receptor Loci by Nuclear Topography8. Regulation of Chromatin Accessibility and V(D)J Recombination by Cis-Acting Elements; 9. Role of Transcription in Accessibility Control of V(D)J Recombination; 10. Transcription Factors Involved in Accessibility Control of Ig and TCR Loci; 11. Control of Recombinase Accessibility by Chromatin Modifications and Remodeling; 12. Concluding Remarks; Acknowledgments; References; Chapter 3: Targeting Integrin Structure and Function in Disease; 1. Introduction; 2. Structure, Ligand-Binding Sites, and Competitive Antagonists 
505 8 |a 3. Large Conformational Changes and Affinity States4. I-Domain Allosteric Site and Antagonists; 5. An Internal Ligand; 6. betaI-Domain Allosteric Regulation; 7. The PSI- and EGF-Domain Restraints; 8. The Cytoplasmic Domain Restraint; 9. Therapeutics; 10. Concluding Remarks; Acknowledgments; References; Chapter 4: Endogenous TLR Ligands and Autoimmunity; 1. Introduction (Short Overview on TLR Immunobiology); 2. The Innate: Adaptive Immune Connection; 3. TLR-Mediated Immunostimulatory Potential of Self-RNA and -DNA; 4. Function of IFN-alpha/beta 
505 8 |a 5. Cytokine-Driven DC Activation: A Portal for Autoimmunity?6. TLRs and Autoimmunity; 7. TLRs and ""Innate Autoimmunity""; Acknowledgments; References; Chapter 5: Genetic Analysis of Innate Immunity; 1. Introduction; 2. How Do We Detect Infection?; 3. Forward and Reverse Genetic Analyses of TLR Signaling; 4. TLR-Independent Detection of Microbes; 5. Global Resistome; 6. Endogenous Activators of TLR Signaling?; 7. Conclusions About Innate Immunity and the Classical Genetic Approach; Acknowledgments; References; Chapter 6: TIM Family of Genes in Immunity and Tolerance; 1. Introduction 
650 0 |a Immunology. 
650 0 |a Microbiology. 
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650 2 |a Microbiology  |0 (DNLM)D008829 
650 6 |a Immunologie.  |0 (CaQQLa)201-0066630 
650 6 |a Microbiologie.  |0 (CaQQLa)201-0003856 
650 7 |a microbiology.  |2 aat  |0 (CStmoGRI)aat300054469 
650 7 |a Immunology  |2 fast  |0 (OCoLC)fst00968006 
650 7 |a Microbiology  |2 fast  |0 (OCoLC)fst01019576 
700 1 |a Alt, Frederick W. 
776 0 8 |i Print version:  |t Advances in immunology.  |d New York : Academic Press, 2005  |w (DLC) 61017057 
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