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Advances in immunology. Vol. 61 /

"The series which all immunologists need."--The Pharmaceutical Journal "Advances in Immunology must find itself among the most active volumes in the libraries of our universities and institutions."--Science "Deserves a permanent place in biomedical libraries as an aid in res...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Dixon, Frank J. (Frank James), 1920-2008, Alt, Frederick W.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: San Diego : Academic Press, �1996.
Colección:Advances in immunology.
Temas:
Acceso en línea:Texto completo
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Tabla de Contenidos:
  • Front Cover; Advances in Immunology, Volume 61; Copyright Page; Contents; Contributors; Chapter 1. CD40-CD40 Ligand: A Multifunctional Receptor-Ligand Pair; I. Introduction; II. CD40 as a Member of the TNF Receptor Superfamily; III. CD40-L as a Member of the TNF Superfamily; IV. Signal Transduction through CD40; V. Functional Consequences of in Vitro CD40 Engagement; VI. In Vivo Role of CD40-CD40-L Interactions; VII. Role of CD40-CD40-L in B Cell Immunopoiesis: A Synthesis; VIII. Perspectives; References; Chapter 2. Antibody Class Switching
  • I. Introduction: Overview and Functions of Different Classes of AntibodiesII. Heavy Chain Isotype Expression during B Cell Differentiation; III. Regulation of Isotype Specificity during Antigen-Dependent Class Switching and Induction of Class Switch Recombination; IV. Mechanism of Switch Recombination; References; Chapter 3. Interleukin-2 Receptor Signaling Mechanisms; I. Introduction; II. IL-2R Structure: Composition of the IL-2R; III. IL-2R-Triggered Proximal Signaling Events; IV. The Ras/MAP Kinase Cascade; V. The PI3-K Pathway; VI. IL-2R Signaling: Jaks and Stats
  • VII. IL-2-Dependent G1-Phase ProgressionVIII. Characterization of the Target Protein of the FKBP12-Rapamycin Complex; IX. Summary and Perspective; References; Chapter 4. Control of the Complement System; I. Overview of Complement Regulation; II. Control of the Initiation Step of the Classical Pathway; III. Control of C3/C5 Convertases on Host Cells; IV. Control of Fluid-Phase C3/C5 Convertases; V. Control of Fluid-Phase MAC; VI. Control of Deposited MAC; VII. Control of Anaphylatoxins; VIII. Summary and Conclusions; References; Chapter 5. V(D)J Recombination Pathology; I. Introduction
  • II. V(D)J RecombinationIII. Components of the V(D)J Recombination Machinery; IV. V(D)J Recombination Defects in Humans; V. Conclusion; References; Chapter 6. Major Histocompatibility Complex Class II Deficiency: A Disease of Gene Regulation; I. Introduction; II. Regulation of MHC Class II Gene Expression; III. Biochemical and Genetic Heterogeneity in BLS; IV. CIITA, the Gene Mutated in Complementation Group A; V. RFX5, the Gene Mutated in Complementation Group C; VI. Function of CIITA; VII. Function of RFX; VIII. Conclusions, Unresolved Questions, and Perspectives; References
  • Chapter 7. TH1-TH2 Cells in Allergic Responses: At the Limits of a ConceptI. Introduction; II. The Regulation of Human IgE Synthesis; III. The Regulatory Potential of T Cells; IV. Mast Cells any Basophil Granulocytes: Innate TH2 Type Cells?; V. APCS and the Antigen Play a Decisive Role for the Onset of a Particular TH Response; VI. The Integrative Role of the Nervous System; VII. Psychological Factors and Allergic Diseases; VIII. Neuroendocrine Factors and IgE Regulation; IX. Concluding Remarks; References; Index; Contents of Recent Volumes