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Advances in immunology. Vol. 61 /
"The series which all immunologists need."--The Pharmaceutical Journal "Advances in Immunology must find itself among the most active volumes in the libraries of our universities and institutions."--Science "Deserves a permanent place in biomedical libraries as an aid in res...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
San Diego :
Academic Press,
�1996.
|
| Colección: | Advances in immunology.
|
| Temas: | |
| Acceso en línea: | Texto completo Texto completo |
MARC
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|---|---|---|---|
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| 003 | OCoLC | ||
| 005 | 20231117033302.0 | ||
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| 019 | |a 1112946158 | ||
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| 020 | |a 9780120224616 |q (electronic bk.) | ||
| 020 | |z 9780080578378 | ||
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| 020 | |a 9780080578378 | ||
| 035 | |a (OCoLC)646797728 |z (OCoLC)1112946158 | ||
| 050 | 4 | |a QR181 |b .A38 1996eb | |
| 082 | 0 | 4 | |a 571.9/6 |2 23 |
| 245 | 0 | 0 | |a Advances in immunology. |n Vol. 61 / |c edited by Frank J. Dixon ; associate editors, Frederick Alt [and others]. |
| 260 | |a San Diego : |b Academic Press, |c �1996. | ||
| 300 | |a 1 online resource (x, 416 pages) : |b illustrations | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 490 | 1 | |a Advances in immunology, |x 0065-2776 | |
| 504 | |a Includes bibliographical references and index. | ||
| 588 | 0 | |a Print version record. | |
| 520 | |a "The series which all immunologists need."--The Pharmaceutical Journal "Advances in Immunology must find itself among the most active volumes in the libraries of our universities and institutions."--Science "Deserves a permanent place in biomedical libraries as an aid in research and in teaching"--Journal of Immunological Methods "A provocative and scholarly review of research"--Journal of the American Medical Association "Provides an extremely valuable source of reference and many stimulating ideas ... the main repository of information in a rapidly devloping subject"--The Lancet "Provides unrivalled value in both academic and fiscal terms and should be purchased by hard pressed librarians as a major priority to be jealously defended."--Journal of Medical Microbiology "A very valuable serial publication ... no serious student of immunology can afford to be without it."--Archives of Biochemistry and Biophysics Key Features * Focus on components of the V(D)J recombination machinery that might be related to diseases in humans and animals * Control of the complement system by control of C3/C5 convertase on host cells, control of fluid phase C3/C5 convertases, control of fluid phase MAC, and control of deposited MAC * Immunodeficiency resulting from a complete absence of MHC class II expression and two trans-acting factors controlling transcription * Current knowledge of IL-2R signaling, highlighting IL-2 signaling, and T-cell growth regulation * Functional role of CD40 in cells, the in vivo significance of CD40-CD40-L interactions, and the signal transduction machinery activated following crosslinking of the CD40 antigen * Integrative approach to better understand the observed heterogeneity of an individual response to allergens * Regulation of isotype specificity, switch recombination regulation, and the mechanism of switching * Two lymphocyte-specific proteins, RAG1 and RAG2, initiate V(D)J recombination of antigen receptor genes | ||
| 505 | 0 | |a Front Cover; Advances in Immunology, Volume 61; Copyright Page; Contents; Contributors; Chapter 1. CD40-CD40 Ligand: A Multifunctional Receptor-Ligand Pair; I. Introduction; II. CD40 as a Member of the TNF Receptor Superfamily; III. CD40-L as a Member of the TNF Superfamily; IV. Signal Transduction through CD40; V. Functional Consequences of in Vitro CD40 Engagement; VI. In Vivo Role of CD40-CD40-L Interactions; VII. Role of CD40-CD40-L in B Cell Immunopoiesis: A Synthesis; VIII. Perspectives; References; Chapter 2. Antibody Class Switching | |
| 505 | 8 | |a I. Introduction: Overview and Functions of Different Classes of AntibodiesII. Heavy Chain Isotype Expression during B Cell Differentiation; III. Regulation of Isotype Specificity during Antigen-Dependent Class Switching and Induction of Class Switch Recombination; IV. Mechanism of Switch Recombination; References; Chapter 3. Interleukin-2 Receptor Signaling Mechanisms; I. Introduction; II. IL-2R Structure: Composition of the IL-2R; III. IL-2R-Triggered Proximal Signaling Events; IV. The Ras/MAP Kinase Cascade; V. The PI3-K Pathway; VI. IL-2R Signaling: Jaks and Stats | |
| 505 | 8 | |a VII. IL-2-Dependent G1-Phase ProgressionVIII. Characterization of the Target Protein of the FKBP12-Rapamycin Complex; IX. Summary and Perspective; References; Chapter 4. Control of the Complement System; I. Overview of Complement Regulation; II. Control of the Initiation Step of the Classical Pathway; III. Control of C3/C5 Convertases on Host Cells; IV. Control of Fluid-Phase C3/C5 Convertases; V. Control of Fluid-Phase MAC; VI. Control of Deposited MAC; VII. Control of Anaphylatoxins; VIII. Summary and Conclusions; References; Chapter 5. V(D)J Recombination Pathology; I. Introduction | |
| 505 | 8 | |a II. V(D)J RecombinationIII. Components of the V(D)J Recombination Machinery; IV. V(D)J Recombination Defects in Humans; V. Conclusion; References; Chapter 6. Major Histocompatibility Complex Class II Deficiency: A Disease of Gene Regulation; I. Introduction; II. Regulation of MHC Class II Gene Expression; III. Biochemical and Genetic Heterogeneity in BLS; IV. CIITA, the Gene Mutated in Complementation Group A; V. RFX5, the Gene Mutated in Complementation Group C; VI. Function of CIITA; VII. Function of RFX; VIII. Conclusions, Unresolved Questions, and Perspectives; References | |
| 505 | 8 | |a Chapter 7. TH1-TH2 Cells in Allergic Responses: At the Limits of a ConceptI. Introduction; II. The Regulation of Human IgE Synthesis; III. The Regulatory Potential of T Cells; IV. Mast Cells any Basophil Granulocytes: Innate TH2 Type Cells?; V. APCS and the Antigen Play a Decisive Role for the Onset of a Particular TH Response; VI. The Integrative Role of the Nervous System; VII. Psychological Factors and Allergic Diseases; VIII. Neuroendocrine Factors and IgE Regulation; IX. Concluding Remarks; References; Index; Contents of Recent Volumes | |
| 546 | |a English. | ||
| 650 | 0 | |a Immunology. | |
| 650 | 0 | |a Allergy. | |
| 650 | 6 | |a Immunologie. |0 (CaQQLa)201-0066630 | |
| 650 | 7 | |a Allergy |2 fast |0 (OCoLC)fst00805549 | |
| 650 | 7 | |a Immunology |2 fast |0 (OCoLC)fst00968006 | |
| 700 | 1 | |a Dixon, Frank J. |q (Frank James), |d 1920-2008. | |
| 700 | 1 | |a Alt, Frederick W. | |
| 776 | 0 | |z 0120224615 | |
| 830 | 0 | |a Advances in immunology. | |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780120224616 |z Texto completo |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/bookseries/00652776/61 |z Texto completo |