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Advances in virus research. Volume 71 /

Published since 1953, Advances in Virus Research covers a diverse range of in-depth reviews providing a valuable overview of the current field of virology. The impact factor for 2006 is 3.48 placing it 7th in the highly competitive category of virology.

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Maramorosch, Karl, Shatkin, Aaron J., Murphy, Frederick A.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam : Academic Press, 2008.
Colección:Advances in virus research ; 71.
Temas:
Acceso en línea:Texto completo

MARC

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245 0 0 |a Advances in virus research.  |n Volume 71 /  |c edited by Karl Maramorosch, Aaron J. Shatkin, Frederick A. Murphy. 
260 |a Amsterdam :  |b Academic Press,  |c 2008. 
300 |a 1 online resource (viii, 256 pages) :  |b illustrations. 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
490 1 |a Advances in virus research ;  |v 71 
504 |a Includes bibliographical references and index. 
588 0 |a Print version record. 
520 |a Published since 1953, Advances in Virus Research covers a diverse range of in-depth reviews providing a valuable overview of the current field of virology. The impact factor for 2006 is 3.48 placing it 7th in the highly competitive category of virology. 
505 0 |a Front Cover; Advances in Virus Research; Copyright Page; Contents; Chapter 1: The Pathogenesis of Poliomyelitis: What We Don't Know; I. Introduction; II. Sequential Steps in the Spread of Infection; A. Questions unanswered: Cellular sites of replication; B. Questions unanswered: Neural invasion from the blood; III. Provocation Poliomyelitis; A. Questions unanswered: The mechanism of the provoking effect; B. Questions unanswered: Neural spread; IV. PVR, Tropism, and the Localization of Lesions; A. Questions unanswered: Receptor expression is necessary but not sufficient 
505 8 |a B. Questions unanswered: Localization within the CNSC. Questions unanswered: How poliovirus kills cells; V. Host Innate and Immune Response to Infection; A. Questions unanswered: The acquired immune response; VI. Immune Defenses and Viral Clearance: Mechanisms of Vaccine-Induced Protection; A. Primary infections; B. Secondary infection in immune hosts; C. Poliovirus serotypes; VII. Animal Models of Human Poliomyelitis; A. Questions unanswered: Determinants of primate susceptibility; B. Questions unanswered: The mechanism of rodent adaptation; C. Questions unanswered: PVR mice 
505 8 |a D. Questions unanswered: The tropism enigmaVIII. Virulence of Polioviruses; A. Questions unanswered: Mechanisms of neurovirulence; B. Questions unanswered: Viremia and virulence; C. Questions unanswered: Epidemiological properties of polioviruses; IX. How Does Poliovirus Persist?; A. Questions unanswered: Overt persistence of poliovirus; B. The post-polio syndrome and covert persistence of poliovirus; X. Eradication; A. Questions unanswered: Why is it so difficult to complete the global eradication of wild polioviruses?; XI. Vaccine-Derived Polioviruses and the Eradication Endgame 
505 8 |a A. Questions unanswered: What strategy should be followed if wild polioviruses are eradicated?XII. Reprise; Acknowledgments; References; Chapter 2: Cutting the Gordian Knot-Development and Biological Relevance of Hepatitis C Virus Cell Culture Systems; I. Introduction; II. Genetic Heterogeneity of HCV-Genotypes, Subtypes, Isolates, and Quasispecies; III. The HCV Genome and Its Encoded Proteins; IV. Host Cell Factors Supporting the HCV Life Cycle; V. Consensus HCV cDNA Clones-Infectious in Transfected Chimpanzees; VI. The Replicon System-Autonomous HCV RNA Replication in Hepatoma Cell Lines 
505 8 |a A. Identification of adaptive mutations led to more efficient replicon systemsB. The study of replicon systems led to identification of highly permissive Huh7 cell lines; VII. Pseudo-Particles Expressing the HCV Envelope Proteins (HCVpp)-A System for the Study of Viral Entry and Neutralization; VIII. The JFH1 Isolate-Generation of Cell Culture Derived HCV (HCVcc) in Full Viral Life Cycle Cell Culture Systems; A. The original and adapted JFH1 cell culture system; B. The J6/JFH1 cell culture system; C. Analysis of HCV buoyant density suggests a role of lipoproteins for the viral life cycle 
546 |a English. 
650 0 |a Virology  |x Research. 
650 0 |a Microbiology. 
650 2 |a Microbiology  |0 (DNLM)D008829 
650 6 |a Virologie  |x Recherche.  |0 (CaQQLa)201-0032557 
650 6 |a Microbiologie.  |0 (CaQQLa)201-0003856 
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650 7 |a Microbiology  |2 fast  |0 (OCoLC)fst01019576 
650 7 |a Virology  |x Research  |2 fast  |0 (OCoLC)fst01167675 
700 1 |a Maramorosch, Karl. 
700 1 |a Shatkin, Aaron J. 
700 1 |a Murphy, Frederick A. 
830 0 |a Advances in virus research ;  |v 71. 
856 4 0 |u https://sciencedirect.uam.elogim.com/science/book/9780123743213  |z Texto completo