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910108s2008 ne a ob 001 0 eng d |
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|a E7B
|b eng
|e pn
|c E7B
|d OCLCQ
|d UBY
|d OCLCQ
|d OPELS
|d OCLCQ
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|a 505088664
|a 1127193380
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|a 9780123743213
|q (electronic bk.)
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|a 0123743214
|q (electronic bk.)
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|a 1281762490
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|a 9781281762498
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|a 9786611762490
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|a 6611762493
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|a 0080888097
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|a 9780080888095
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|a (OCoLC)646767446
|z (OCoLC)505088664
|z (OCoLC)1127193380
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050 |
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|a QR375
|b .A3871 2008eb
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|a 579.2
|2 22
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|a Advances in virus research.
|n Volume 71 /
|c edited by Karl Maramorosch, Aaron J. Shatkin, Frederick A. Murphy.
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260 |
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|a Amsterdam :
|b Academic Press,
|c 2008.
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300 |
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|a 1 online resource (viii, 256 pages) :
|b illustrations.
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336 |
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|a text
|b txt
|2 rdacontent
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337 |
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|a computer
|b c
|2 rdamedia
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338 |
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|a online resource
|b cr
|2 rdacarrier
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490 |
1 |
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|a Advances in virus research ;
|v 71
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504 |
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|a Includes bibliographical references and index.
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588 |
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|a Print version record.
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520 |
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|a Published since 1953, Advances in Virus Research covers a diverse range of in-depth reviews providing a valuable overview of the current field of virology. The impact factor for 2006 is 3.48 placing it 7th in the highly competitive category of virology.
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505 |
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|a Front Cover; Advances in Virus Research; Copyright Page; Contents; Chapter 1: The Pathogenesis of Poliomyelitis: What We Don't Know; I. Introduction; II. Sequential Steps in the Spread of Infection; A. Questions unanswered: Cellular sites of replication; B. Questions unanswered: Neural invasion from the blood; III. Provocation Poliomyelitis; A. Questions unanswered: The mechanism of the provoking effect; B. Questions unanswered: Neural spread; IV. PVR, Tropism, and the Localization of Lesions; A. Questions unanswered: Receptor expression is necessary but not sufficient
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505 |
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|a B. Questions unanswered: Localization within the CNSC. Questions unanswered: How poliovirus kills cells; V. Host Innate and Immune Response to Infection; A. Questions unanswered: The acquired immune response; VI. Immune Defenses and Viral Clearance: Mechanisms of Vaccine-Induced Protection; A. Primary infections; B. Secondary infection in immune hosts; C. Poliovirus serotypes; VII. Animal Models of Human Poliomyelitis; A. Questions unanswered: Determinants of primate susceptibility; B. Questions unanswered: The mechanism of rodent adaptation; C. Questions unanswered: PVR mice
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|a D. Questions unanswered: The tropism enigmaVIII. Virulence of Polioviruses; A. Questions unanswered: Mechanisms of neurovirulence; B. Questions unanswered: Viremia and virulence; C. Questions unanswered: Epidemiological properties of polioviruses; IX. How Does Poliovirus Persist?; A. Questions unanswered: Overt persistence of poliovirus; B. The post-polio syndrome and covert persistence of poliovirus; X. Eradication; A. Questions unanswered: Why is it so difficult to complete the global eradication of wild polioviruses?; XI. Vaccine-Derived Polioviruses and the Eradication Endgame
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|a A. Questions unanswered: What strategy should be followed if wild polioviruses are eradicated?XII. Reprise; Acknowledgments; References; Chapter 2: Cutting the Gordian Knot-Development and Biological Relevance of Hepatitis C Virus Cell Culture Systems; I. Introduction; II. Genetic Heterogeneity of HCV-Genotypes, Subtypes, Isolates, and Quasispecies; III. The HCV Genome and Its Encoded Proteins; IV. Host Cell Factors Supporting the HCV Life Cycle; V. Consensus HCV cDNA Clones-Infectious in Transfected Chimpanzees; VI. The Replicon System-Autonomous HCV RNA Replication in Hepatoma Cell Lines
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|a A. Identification of adaptive mutations led to more efficient replicon systemsB. The study of replicon systems led to identification of highly permissive Huh7 cell lines; VII. Pseudo-Particles Expressing the HCV Envelope Proteins (HCVpp)-A System for the Study of Viral Entry and Neutralization; VIII. The JFH1 Isolate-Generation of Cell Culture Derived HCV (HCVcc) in Full Viral Life Cycle Cell Culture Systems; A. The original and adapted JFH1 cell culture system; B. The J6/JFH1 cell culture system; C. Analysis of HCV buoyant density suggests a role of lipoproteins for the viral life cycle
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546 |
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|a English.
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650 |
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0 |
|a Virology
|x Research.
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650 |
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0 |
|a Microbiology.
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650 |
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2 |
|a Microbiology
|0 (DNLM)D008829
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650 |
|
6 |
|a Virologie
|x Recherche.
|0 (CaQQLa)201-0032557
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650 |
|
6 |
|a Microbiologie.
|0 (CaQQLa)201-0003856
|
650 |
|
7 |
|a microbiology.
|2 aat
|0 (CStmoGRI)aat300054469
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650 |
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7 |
|a Microbiology
|2 fast
|0 (OCoLC)fst01019576
|
650 |
|
7 |
|a Virology
|x Research
|2 fast
|0 (OCoLC)fst01167675
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700 |
1 |
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|a Maramorosch, Karl.
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700 |
1 |
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|a Shatkin, Aaron J.
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700 |
1 |
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|a Murphy, Frederick A.
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830 |
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0 |
|a Advances in virus research ;
|v 71.
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856 |
4 |
0 |
|u https://sciencedirect.uam.elogim.com/science/book/9780123743213
|z Texto completo
|