|
|
|
|
LEADER |
00000cam a2200000Ma 4500 |
001 |
SCIDIR_ocn646759078 |
003 |
OCoLC |
005 |
20231117033256.0 |
006 |
m o d |
007 |
cr cn||||||||| |
008 |
840822s1990 caua ob 001 0 eng d |
040 |
|
|
|a E7B
|b eng
|e pn
|c E7B
|d OCLCQ
|d OPELS
|d OCLCQ
|d OCLCF
|d OCLCQ
|d DEBSZ
|d VLY
|d OCLCO
|d OCL
|d OCLCQ
|d OCLCO
|
019 |
|
|
|a 1162113451
|
020 |
|
|
|a 012469537X
|q (electronic bk.)
|
020 |
|
|
|a 9780124695375
|q (electronic bk.)
|
020 |
|
|
|a 1281749478
|
020 |
|
|
|a 9781281749475
|
020 |
|
|
|a 9786611749477
|
020 |
|
|
|a 6611749470
|
020 |
|
|
|a 0080865615
|
020 |
|
|
|a 9780080865614
|
035 |
|
|
|a (OCoLC)646759078
|z (OCoLC)1162113451
|
050 |
|
4 |
|a QD421.A1
|b A4337 1990eb
|
082 |
0 |
4 |
|a 572/.549
|2 23
|
245 |
0 |
4 |
|a The alkaloids.
|n Volume 37,
|p Antitumor bisindole alkaloids from catharanthus roseus (L) /
|c edited by Arnold Brossi, Matthew Suffness.
|
260 |
|
|
|a San Diego ;
|a London :
|b Academic Press,
|c �1990.
|
300 |
|
|
|a 1 online resource (ix, 250 pages) :
|b illustrations.
|
336 |
|
|
|a text
|b txt
|2 rdacontent
|
337 |
|
|
|a computer
|b c
|2 rdamedia
|
338 |
|
|
|a online resource
|b cr
|2 rdacarrier
|
490 |
0 |
|
|a Alkaloids. ;
|v v. 37
|
504 |
|
|
|a Includes bibliographical references and index.
|
588 |
0 |
|
|a Print version record.
|
505 |
0 |
|
|a Front Cover; The Alkaloids, Volume 37; Copyright Page; CONTENTS; Contributors; Preface; Chapter 1. Isolation, Structure Elucidation, and Biosynthesis of the Bisindole Alkaloids of Catharanthus; I. Introduction; II. Structure Elucidation and Spectroscopy; III. Biosynthesis; IV. Summary; References; Chapter 2. Syntheses of Vinblastine-Type Alkaloids; I. Introduction; II. Hydroxyalkylindole Route; III. Chloroindolenine Route; IV. �-Carboline Coupling; V. Biomimetic Approach; VI. New Strategies for Generation of C-16'-C-14' PARF Relative Stereochemistry; References
|
505 |
8 |
|
|a Chapter 3. Functional Hot Spot at the C-20' Position of VinblastineI. Introduction; II. C-20' Modifications; III. Molecular Constraints of Congener Activity; IV. Conclusions; References; Chapter 4. Medicinal Chemistry of Bisindole Alkaloids From Catharanthus; I. Introduction; II. Pharmacology; III. Physicochemical Considerations; IV. Naturally Occurring Bisindole Alkaloids from Catharanthus; V. Modifications of the Upper Half (Velbanamine Portion) of Bisindole Alkaloids; VI. Modifications of the Lower Half (Vindoline Portion) of Bisindole Alkaloids
|
505 |
8 |
|
|a VII. Multiple Modifications: 4'-EpideoxyvincristineVIII. New Concepts in Medicinal Chemistry of Bisindole Alkaloids; IX. Conclusions; References; Chapter 5. Pharmacology of Antitumor Bisindole Alkaloids from Catharanthus; I. Introduction; II. Biochemical Pharmacology; III. Cellular Pharmacology; IV. Preclinical Pharmacology; V. Preclinical Toxicology; VI. Clinical Pharmacology; VII. Clinical Toxicology; References; Chapter 6. The Therapeutic Use of Bisindole Alkaloids from Catharanthus; I. History of Therapeutic Use; II. Current Therapeutic Use; III. Toxicity; IV. Mechanism of Action
|
505 |
8 |
|
|a V. Drug ResistanceReferences; Cumulative Index of Titles; Index
|
520 |
|
|
|a The Alkaloids: Antitumor Bisindole Alkaloids from Catharanthus roseus (L.) V37.
|
546 |
|
|
|a English.
|
650 |
|
0 |
|a Alkaloids
|x Physiological effect.
|
650 |
|
0 |
|a Antineoplastic agents.
|
650 |
|
0 |
|a Antimitotic agents.
|
650 |
|
6 |
|a Alcalo�ides
|x Effets physiologiques.
|0 (CaQQLa)201-0097058
|
650 |
|
6 |
|a Anticanc�ereux.
|0 (CaQQLa)201-0004692
|
650 |
|
7 |
|a Antimitotic agents
|2 fast
|0 (OCoLC)fst00810570
|
650 |
|
7 |
|a Alkaloids
|x Physiological effect
|2 fast
|0 (OCoLC)fst00805401
|
650 |
|
7 |
|a Antineoplastic agents
|2 fast
|0 (OCoLC)fst00810595
|
700 |
1 |
|
|a Brossi, Arnold.
|
700 |
1 |
|
|a Suffness, Matthew.
|
776 |
|
|
|z 0-12-469537-X
|
856 |
4 |
0 |
|u https://sciencedirect.uam.elogim.com/science/book/9780124695375
|z Texto completo
|