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Vitamins and hormones : advances in research and applications. Volume 53, Cell death proteins /
Cell death is one of the fundamental processes by which normal development is modulated, and the importance of both necrosis and apoptosis in a number of pathologies has generated intense interest from researchers in many fields. This timely book covers both the proteins that are produced by dying c...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
San Diego ; London :
Academic Press,
�1997.
|
| Colección: | Vitamins and hormones ;
v. 53. |
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 082 | 0 | 4 | |a 572/.58 |2 23 |
| 245 | 0 | 0 | |a Vitamins and hormones : |b advances in research and applications. |n Volume 53, |p Cell death proteins / |c edited by Gerald Litwack. |
| 246 | 3 | 0 | |a Cell death proteins |
| 260 | |a San Diego ; |a London : |b Academic Press, |c �1997. | ||
| 300 | |a 1 online resource (xi, 198 pages). | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 490 | 1 | |a Vitamins and hormones ; |v v. 53 | |
| 504 | |a Includes bibliographical references and index. | ||
| 588 | 0 | |a Print version record. | |
| 520 | |a Cell death is one of the fundamental processes by which normal development is modulated, and the importance of both necrosis and apoptosis in a number of pathologies has generated intense interest from researchers in many fields. This timely book covers both the proteins that are produced by dying cells and the proteins that signal cells to initiate cell death. Cell Death Proteins provides an overview of the explosive interest in cellular death. Six review papers, written by researchers at the forefront of this rapidly moving field, focus on proteins that promote, signal, and inhibit cell death. Major players involved in the cell death cascade and its controls are covered, including cell cycle checkpoints, the function of interleukin-1J converting enzyme, the role of IGF-I receptor, the Bcl-2 family of proteins, viral inhibitors of apoptosis, and p53-dependent apoptosis. | ||
| 505 | 0 | |a Front Cover; Vitamins and Hormones, Volume 53; Copyright Page; Contents; Preface; Chapter 1. Cell Cycle Checkpoints and Apoptosis: Potential for Improving Radiation Therapy; I. Introduction; II. Apoptosis; III. Linkage of Cell Cycle Checkpoints to Apoptosis; IV. Regulation of Cell Proliferation and the Control of Apoptosis; V. Effect of Oncogenes on Radiation-Induced Apoptosis; VI. Therapeutic Implications; References; Chapter 2. Structure and Function of Interleukin-1� Converting Enzyme; I. lntroduction; II. The IL-1 System; III. Molecular and Biochemical Characterization of ICE | |
| 505 | 8 | |a IV ICE Gene Family MembersV. Biological Role of ICE; VI. Summary; References; Chapter 3. The Role of the IGF-I Receptor in Apoptosis; I. Introduction; II. The IGF-I Receptor in Mitogenesis; III. The Signal-Transducing Pathways of the IGF-I Receptor; IV. The IGF-I Receptor in Transformation; V. Mutational Analysis of the IGF-I Receptor; VI. The IGF-I Receptor and Its Ligands in Apoptosis; VII. The in Vivo Method for Determining the Extent of Apoptosis; VIII. The IGF-I Receptor Protects Tumor Cells from Apoptosis in Vivo; IX. The IGF-I Receptor and Apoptosis in Normal Cells | |
| 505 | 8 | |a X. Dominant NegativesXI. Critique of Antisense Strategies; XII. Mechanisms; XIII. Host Respones; XTV. Significance; References; Chapter 4. Bcl-2 Family Proteins and the Hormonal Control of Cell Life and Death in Normalcy and Neoplasia; I. Introduction; II. The Bcl-2 Protein Family; III. Mechanisms of Bcl-2 Protein Action; IV. Bcl-2 Family Proteins as Determinants of Tumor Resistance to Chemotherapeutic Drugs, Glucocorticoids, Retinoids, Antiandrogens, and Antiestrogens; V. In Vivo Patterns of Bcl-2 Family Gene Expression in Hormone- Dependent Tissues and Tumors Derived from Them | |
| 505 | 8 | |a VI . ConclusionsReferences; Chapter 5. Pathways of p53-Dependent Apoptosis; I. Introduction; II. Dual Personality of the p53 Tumor Suppressor Protein; III. Oncogene-Driven p53-Dependent Apoptosis; IV. Coupling of p53-Dependent Cell Cycle RegulatoryPathways and Apoptosis; V. Downstream Effector Genes of p53-Dependent Apoptosis:The Bcl-2 Bax Connection; VI. Growth Factors, Cytokines, and Survival Factors; VII. Role of p53-Mediated Modulation of Transcription; References; Chapter 6. Viral Inhibitors of Apoptosis; I. Introduction; II. Viral Proteins That Resemble Bcl-2 | |
| 505 | 8 | |a III. Viral Proteins That Inactivate p53IV. Inactivators of Apoptotic Cysteine Proteases; V. Inhibitor of Apoptosis Proteins; VI . Virus-Encoded Cytokine Regulators; VII. Other Viral Inhibitors of Apoptosis; VIII. Conclusions; References; Index | |
| 546 | |a English. | ||
| 650 | 0 | |a Cell death. | |
| 650 | 0 | |a Hormones. | |
| 650 | 6 | |a Cellules |x Mort. |0 (CaQQLa)201-0110794 | |
| 650 | 6 | |a Hormones. |0 (CaQQLa)201-0017163 | |
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| 700 | 1 | |a Litwack, Gerald. | |
| 776 | 0 | 8 | |i Print version: |t Vitamins and hormones. |d San Diego ; London : Academic Press, �1997 |w (DLC) 43010535 |
| 830 | 0 | |a Vitamins and hormones ; |v v. 53. | |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780127098531 |z Texto completo |