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Drug-drug interactions : scientific and regulatory perspectives /
Drug-Drug Interactions is a comprehensive review of the scientific and regulatory perspectives of drug-drug interactions from the point-of-view of academia, industry, and government regulatory agencies. This book is intended for professionals in the pharmaceutical industry, health care, and governme...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
San Diego, Calif. :
Academic Press,
�1997.
|
| Colección: | Advances in pharmacology ;
v. 43. |
| Temas: | |
| Acceso en línea: | Texto completo Texto completo |
Tabla de Contenidos:
- Overview : pharmacokinetic drug-drug interactions / Albert P. Li and Malle Jurima-Romet
- Role of cytochrome P450 enzymes in drug-drug interactions / F. Peter Guengerich
- Liver as a target for chemical-chemical interactions / John-Michael Sauer [and others]
- Application of human liver microsomes in metabolism-based drug-drug interactions : in vitro-in vivo correlations and the Abbott Laboratories experience / A. David Rodrigues and Shekman L. Wong
- Primary hepatocyte cultures as an in vitro experimental model for the evaluation of pharmacokinetic drug-drug interactions / Albert P. Li
- Liver slices as a model in drug metabolism / James L. Ferrero and Klaus Brendel
- Use of cDNA-expressed human cytochrome P450 enzymes to study potential drug-drug interactions / Charles L. Crespi and Bruce W. Penman.
- Pharmacokinetics of drug interactions / Gregory L. Kedderis
- Experimental models for evaluating enzyme induction potential of new drug candidates in animals and humans and a strategy for their use / Thomas N. Thompson
- Metabolic drug-drug interactions : perspective from FDA medical and clinical pharmacology reviewers / John Dikran Balian and Atiqur Rahman
- Drug interactions : perspectives of the Canadian Drugs Directorate / Malle Jurima-Romet
- Overview of experimental approaches for study of drug metabolism and drug-drug interactions / Frank J. Gonzalez.