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Annual reports in medicinal chemistry. Volume 34.

Annual Reports in Medicinal Chemistry continues to strive to provide timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences which are expected to provide the basis for entirely new future therapies. Volume 34 ret...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: American Chemical Society. Division of Medicinal Chemistry
Otros Autores: Doherty, Annette M. (Annette Marian), 1961-
Formato: Electrónico eBook
Idioma:Inglés
Publicado: San Diego, Calif. ; London : Academic Press, 1999.
Colección:Annual reports in medicinal chemistry ; v. 34
Temas:
Acceso en línea:Texto completo

MARC

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245 0 0 |a Annual reports in medicinal chemistry.  |n Volume 34. 
260 |a San Diego, Calif. ;  |a London :  |b Academic Press,  |c 1999. 
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490 0 |a Annual reports in medicinal chemistry ;  |v v. 34 
504 |a Includes bibliographical references and indexes. 
588 0 |a Print version record. 
520 |a Annual Reports in Medicinal Chemistry continues to strive to provide timely and critical reviews of important topics in medicinal chemistry together with an emphasis on emerging topics in the biological sciences which are expected to provide the basis for entirely new future therapies. Volume 34 retains the familiar format of previous volumes, this year with 33 chapters. Sections I-IV are disease-oriented and generally report on specific medicinal agents with updates from Volume 33 on antithrombotics, neurokinin receptor antagonists, anticoagualants, and new antibacterials. As in past volumes, annual updates have been limited to only the most active areas of research in favor of specifically focused and mechanistically oriented chapters, where the objective is to provide the reader with the most important new results in a particular field. Sections V and VI continue to emphasize important topics in medicinal chemistry, biology, and drug design as well as the critical interfaces among these disciplines. This volume concludes with To Market, To Market--a chapter on NCE and NBE introductions worldwide in 1998, a chapter on pharmagenomics, and finally one on malaria as a third world disease in need of a first world drug development. 
505 0 |a Front Cover; Annual Reports in Medcinal Chemistry, Volume 34; Copyright Page; CONTENT; CONTRIBUTORS; PREFACE; SECTION I: CENTRAL NERVOUS SYSTEM DISEASES; Chapter 1. Recent Approaches to Novel Antidepressant Therapy; Chapter 2. Recent Progress in Corticotropin-Releasing Factor Receptor Agents; Chapter 3. �-Amyloid as a Target for Alzheimer's Disease Therapy; Chapter 4. Recent Advances in the Development of Neuropeptide Y Receptor Antagonists; Chapter 5. Pharmacological Interventions in the Sleep Process; Chapter 6. Progress in the Development of Neurokinin Antagonists 
505 8 |a SECTION II: CARDIOVASCULAR AND PULMONARY DISEASESChapter 7. Recent Approaches Towards Inhibiting Allergic Eosinophilia; Chapter 8. Pharmacological Therapy for the Treatment of Erectile Dysfunction; Chapter 9. Anticoagulants: Thrombin and Factor Xa Inhibitors; Chapter 10. Atherosclerosis: Emerging Pharmacological Approaches; Chapter 11. Current and Potential New Therapies for Chronic Obstructive; SECTION III: CANCER AND INFECTIOUS DISEASES; Chapter 12. The Urokinase-type Plasminogen Activator and Its Receptor in Cancer; Chapter 13. Progress in the Search for Anti-HCV Therapeutics 
505 8 |a Chapter 14. Antimitotic AgentsChapter 15. DNA Vaccines Coming of Age; Chapter 16. Development of Anti-Malarial Inhibitors of Hemoglobinases; Chapter 17. New Antibacterials for Resistant Organisms; SECTION IV: IMMUNOLOGY, ENDOCRINOLOGY AND METABOLIC DISEASES; Chapter 18. Inhibitors of lntegrin Alpha 4 Beta 1 (VLA-4); Chapter 19. Glucagon and Glucagon-Like Peptide-; Chapter 20. Pharmacology of Cannabinoid Receptor Agonists and Antagonists; Chapter 21. Non-peptide Somatostatin Receptor Ligands; SECTION V: TOPICS IN BIOLOGY; Chapter 22. Cytokines in T Cell Maturation 
505 8 |a Chapter 23. Genomics, Target Selection, Validation, and Assay ConsiderationsChapter 24. The Case for Recombinant Production of Pharmaceutical Proteins in; Chapter 25. New Targets in Cell Cycle Regulation; Chapter 26. New Targets in Autoimmune Diseases; SECTION VI: TOPICS IN DRUG DESIGN AND DISCOVERY; Chapter 27. Application of Combinatorial and Parallel Synthesis to Medicinal; Chapter 28. Recent Developments in Molecular Diversity: Computational Approaches to Combinatorial Chemistry; Chapter 29. Structure-Based Drug Design 
505 8 |a Chapter 30. Using Mass Spectrometry to Determine ADME Properties in Drug DiscoverySECTION VII: TRENDS AND PERSPECTIVES; Chapter 31. To Market, To Market -- 1998; Chapter 32. Pharmacogenomics and its Impact on Drug Design and Optimisation; Chapter 33. Malaria: A Third World Disease in Need of First World Drug Development; COMPOUND NAME, CODE NUMBER AND SUBJECT INDEX, VOLUME 34; CUMULATIVE CHAPTER TITLES KEYWORD INDEX, VOLUMES 1-34; CUMULATIVE NCE INTRODUCTION INDEX, 1983-1998; CUMULATIVE NCE INTRODUCTION INDEX, 1983-1998, BY INDICATION 
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700 1 |a Doherty, Annette M.  |q (Annette Marian),  |d 1961- 
710 2 |a American Chemical Society.  |b Division of Medicinal Chemistry. 
776 0 8 |i Print version:  |t Annual reports in medicinal chemistry. Volume 34.  |d San Diego : Academic Press, �1999  |z 9780120405343 
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