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Current topics in developmental biology. Volume 47, Somitogenesis. Part I /

The chapters contained in this two-volume set provide a broad perspective on the novel strategies and conceptual paradigms that drive the current resurgence of interest in somitogenesis - the process by which somites form and elaborate differentiated tissues and structures. Because somites are a ubi...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Ordahl, Charles P.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York : Academic Press, 2000.
Colección:Current topics in developmental biology ; 47.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Front Cover; Somitogenesis: Part 1; Copyright Page; Contents; Contributors; Preface; Chapter 1. Early Events of Somitogenesis in Higher Vertebrates: Allocation of Precursor Cells during Gastrulation and the Organization of a Meristic Pattern in the Paraxial Mesoderm; I. Anatomy of the Paraxial Mesoderm; II. Localization of the Somitic Precursor Cells; III. Development Plasticity and Commitment to Somitic Fate; IV. Does a Prepattern of Segmentation Exist in the Presomitic Mesoderm?; V. Unanswered Questions; References
  • Chapter 2. Retrospective Tracing of the Developmental Lineage of the Mouse MyotomeI. Introduction; II. The LaacZ Method; III. The Basic Logic of Clonal Analysis; IV. The Myotome in the E11.5 Mouse Embryo; V. The Questions; VI. The clones; VII . The Longitudinal Organization of the Segments; VIII. A Model for the Longitudinal Organization of the Muscle System; IX. The Mediolateral Organization of the Segments; X. A Model for the Mediolateral Organization of the Muscle System; XI. Conclusion; References; Chapter 3. Segmentation of the Paraxial Mesoderm and Vertebrate Somitogenesis
  • I. Definition of the Mesodermal SegmentII. Models for Somite Formation; III. Molecular Aspects of Vertebrate Somitogenesis; IV. A Model for Vertebrate Segmentation and Somitogenesis; References; Chapter 4. Segmentation: A View from the Border; I. Introduction; II. Segments and Parasegments; III. Three Models for the Control of Somite Formation; IV. A Molecular Clock; V. Two Interpretations of the c-huiry-1 Clock; VI. The Molecular Basis of Boundary Formation; VII. The Molecular Basis of Boundary Maintenance; VIII. Determination of Somite Identity; References
  • Chapter 5. Genetic Regulation of Somite FormationI. Introduction; II. The Role of Basic Helix-Loop-Helix Transcription Factors in Somitogenesis; III. The Role of Notch Signaling in Segmentation; IV. Summary; References; Chapter 6. Hox Genes and the Global Patterning of the Somitic Mesoderm; I. Introduction; II. Patterns in the Mesoderm; III. Mechanisms for Global Patterning; IV. Conclusions; References; Chapter 7. The Origin and Morphogenesis of Amphibian Somites; I. Introduction; II. Origins: Fate Maps and Movements of the Presomitic Mesoderm Are Variable among Amphibians
  • III. A Life before Segmentation: The Geometry, Behavior, and Function of the Prospective Somitic Mesoderm during Gastrulation of XenopusIV. Segmentation and Somite Formation in Xenopus laevis: Cell Elongation and Rotation; V. Variations on a Theme: Somite and Myotome Formation in Other Anurans: Bombina, Gastrotheca, Bufo, Pelobates, and Rana; VI. The Dermatome and Sclerotome; VII. Patterning of the Somitic Mesoderm by Adjacent Tissues; VIII. How Do Cells Decide Where to Make an Intersomitic Furrow?; IX . Role of Morphomechanical Molecules in Segmentation, Somite Morphogenesis; X. Conclusions