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|a 571.8/6
|2 23
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|a Current topics in developmental biology.
|n Volume 47,
|p Somitogenesis.
|n Part I /
|c edited by Charles P. Ordahl.
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|a New York :
|b Academic Press,
|c 2000.
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|a 1 online resource (xii, 319 pages) :
|b illustrations.
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|a online resource
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|a Current topics in developmental biology ;
|v 47
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|a Print version record.
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|a The chapters contained in this two-volume set provide a broad perspective on the novel strategies and conceptual paradigms that drive the current resurgence of interest in somitogenesis - the process by which somites form and elaborate differentiated tissues and structures. Because somites are a ubiquitous feature of vertebrate embryos, they can be studied in a variety of experimental animal models including those amenable to genetic (zebrafish, mammalian), molecular/genetic (mammalian, avian) as well as those already well established for classical experimental embryological and cell biological studies (amphibians, avian). The wide variety of experimental approaches to somitogenesis that are presented in these volumes will leave the reader with a broad perspective on how current research in somitogenesis is helping to solve fundamental questions in vertebrate development and morphogenesis.
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|a References
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|a Front Cover; Somitogenesis: Part 1; Copyright Page; Contents; Contributors; Preface; Chapter 1. Early Events of Somitogenesis in Higher Vertebrates: Allocation of Precursor Cells during Gastrulation and the Organization of a Meristic Pattern in the Paraxial Mesoderm; I. Anatomy of the Paraxial Mesoderm; II. Localization of the Somitic Precursor Cells; III. Development Plasticity and Commitment to Somitic Fate; IV. Does a Prepattern of Segmentation Exist in the Presomitic Mesoderm?; V. Unanswered Questions; References
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|a Chapter 2. Retrospective Tracing of the Developmental Lineage of the Mouse MyotomeI. Introduction; II. The LaacZ Method; III. The Basic Logic of Clonal Analysis; IV. The Myotome in the E11.5 Mouse Embryo; V. The Questions; VI. The clones; VII . The Longitudinal Organization of the Segments; VIII. A Model for the Longitudinal Organization of the Muscle System; IX. The Mediolateral Organization of the Segments; X. A Model for the Mediolateral Organization of the Muscle System; XI. Conclusion; References; Chapter 3. Segmentation of the Paraxial Mesoderm and Vertebrate Somitogenesis
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|a I. Definition of the Mesodermal SegmentII. Models for Somite Formation; III. Molecular Aspects of Vertebrate Somitogenesis; IV. A Model for Vertebrate Segmentation and Somitogenesis; References; Chapter 4. Segmentation: A View from the Border; I. Introduction; II. Segments and Parasegments; III. Three Models for the Control of Somite Formation; IV. A Molecular Clock; V. Two Interpretations of the c-huiry-1 Clock; VI. The Molecular Basis of Boundary Formation; VII. The Molecular Basis of Boundary Maintenance; VIII. Determination of Somite Identity; References
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|a Chapter 5. Genetic Regulation of Somite FormationI. Introduction; II. The Role of Basic Helix-Loop-Helix Transcription Factors in Somitogenesis; III. The Role of Notch Signaling in Segmentation; IV. Summary; References; Chapter 6. Hox Genes and the Global Patterning of the Somitic Mesoderm; I. Introduction; II. Patterns in the Mesoderm; III. Mechanisms for Global Patterning; IV. Conclusions; References; Chapter 7. The Origin and Morphogenesis of Amphibian Somites; I. Introduction; II. Origins: Fate Maps and Movements of the Presomitic Mesoderm Are Variable among Amphibians
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|a III. A Life before Segmentation: The Geometry, Behavior, and Function of the Prospective Somitic Mesoderm during Gastrulation of XenopusIV. Segmentation and Somite Formation in Xenopus laevis: Cell Elongation and Rotation; V. Variations on a Theme: Somite and Myotome Formation in Other Anurans: Bombina, Gastrotheca, Bufo, Pelobates, and Rana; VI. The Dermatome and Sclerotome; VII. Patterning of the Somitic Mesoderm by Adjacent Tissues; VIII. How Do Cells Decide Where to Make an Intersomitic Furrow?; IX . Role of Morphomechanical Molecules in Segmentation, Somite Morphogenesis; X. Conclusions
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|a English.
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|a Somite.
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|a Morphogenesis.
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|a Somite.
|0 (CaQQLa)201-0017269
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|a Morphogenesis
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|0 (OCoLC)fst01026447
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|a Somite
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|0 (OCoLC)fst01125773
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|a Ordahl, Charles P.
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|i Print version:
|t Current topics in developmental biology. Volume 47, Somitogenesis. Part I.
|d New York : Academic Press, 2000
|w (DLC) 66028604
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|a Current topics in developmental biology ;
|v 47.
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|u https://sciencedirect.uam.elogim.com/science/book/9780121531478
|z Texto completo
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