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Current topics in membranes. Volume 47, Amiloride-sensitive sodium channels: physiology and functional diversity /
Sodium reabsorbing epithelia play a major role in whole-body sodium homeostasis. Some examples of sodium regulating tissues include kidney, colon, lung, and sweat ducts. Sodium transport across these membranes is a two-step process: entry through an amiloride-sensitive sodium channel and exit via th...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
San Diego :
Academic Press,
1999.
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| Colección: | Current topics in membranes ;
47. |
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Chapter 4. Cell-Specific Expression of ENaC and Its Regulation by Aldosterone and Vasopressin in Kidney and ColonI. Introduction; II. Cell-Specific Expression; III. Regulation of ENaC Expression by Aldosterone and Vasopressin; References; Chapter 5. Regulation of ENaC by Interacting Proteins and by Ubiquitination; I. Introduction; II. Proline-Rich Regions in ENaC and Their Interacting Proteins; III. Nedd4: Its Domains and Mode of Interaction with ENaC; IV. Regulation of ENaC Stability and Function by Ubiquitination; V. Role of the C2 Domain of Nedd4 in Ca2+-Dependent Membrane Targeting
- VI. SummaryReferences; Chapter 6. Role of G Proteins in the Regulation of Apical Membrane Sodium Permeability by Aldosterone in Epithelia; I. Introduction; II. Control of Basal Na+ Transport by G Proteins; III. GTP-Dependent Methylation of Membrane Proteins; IV. Control of Basal Na+ Permeability by Methylation; V. Aldosterone-Dependent Methylation of Membrane Proteins; VI. Aldosterone-Dependent Membrane GTPase Activity; VII. The Effect of Pertussis Toxin on Membrane Na+ Transport and GTPase Activity; VIII. The Effect of Aldosterone on G-Protein Expression; IX. Conclusion; References
- Chapter 7. The Role of Posttranslational Modifications of Proteins in the Cellular Mechanism of Action of AldosteroneReferences; Chapter 8. Regulation of Amiloride-Sensitive Na+ Channels in the Renal Collecting Duct; I. Introduction; II. Vasopressin Can Act as an Antinatriuretic as Well as an Antidiuretic Hormone; III. Autacoids That Limit the Actions of Aldosterone and Vasopression in the CCD; IV. Trafficking and the Regulation of the Amiloride-Sensitive Na+ Channel; V. A Challenge for Integrative Physiology-The Link between Na+ Retention and Hypertension; References