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Current topics in membranes. Volume 47, Amiloride-sensitive sodium channels: physiology and functional diversity /
Sodium reabsorbing epithelia play a major role in whole-body sodium homeostasis. Some examples of sodium regulating tissues include kidney, colon, lung, and sweat ducts. Sodium transport across these membranes is a two-step process: entry through an amiloride-sensitive sodium channel and exit via th...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
San Diego :
Academic Press,
1999.
|
| Colección: | Current topics in membranes ;
47. |
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 245 | 0 | 0 | |a Current topics in membranes. |n Volume 47, |p Amiloride-sensitive sodium channels: physiology and functional diversity / |c edited by Dale J. Benos. |
| 246 | 3 | 0 | |a Amiloride-sensitive sodium channels : |b physiology and functional diversity |
| 260 | |a San Diego : |b Academic Press, |c 1999. | ||
| 300 | |a 1 online resource (xiii, 384 pages) : |b illustrations. | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 490 | 1 | |a Current topics in membranes ; |v 47 | |
| 504 | |a Includes bibliographical references and index. | ||
| 588 | 0 | |a Print version record. | |
| 520 | |a Sodium reabsorbing epithelia play a major role in whole-body sodium homeostasis. Some examples of sodium regulating tissues include kidney, colon, lung, and sweat ducts. Sodium transport across these membranes is a two-step process: entry through an amiloride-sensitive sodium channel and exit via the ouabain-sensitive sodium/potassium ATPase. The sodium entry channels are the rate-limiting determinant for transport and are regulated by several different hormones. The sodium channels also play a significant role in a number of disease states, like hypertension, edema, drug-induced hyperkalemia, and cystic fibrosis. Amiloride-Sensitive Sodium Channels: Physiology and Functional Diversity provides the first in-depth exchange of ideas concerning these sodium channels, their regulation and involvement in normal and pathophysiological situations. Key Features * Summarizes current state of amiloride-sensitive sodium channel field * Analyzes structure-function of epithelial sodium channels * Discusses immunolocalization of epithelial sodium channels * Examines hormonal regulation of sodium channels * Discusses sodium channels in lymphocytes, kidney, and lung * Considers mechanosensitivity of sodium channels * Provides ideas on sodium channels and disease. | ||
| 505 | 8 | |a Chapter 4. Cell-Specific Expression of ENaC and Its Regulation by Aldosterone and Vasopressin in Kidney and ColonI. Introduction; II. Cell-Specific Expression; III. Regulation of ENaC Expression by Aldosterone and Vasopressin; References; Chapter 5. Regulation of ENaC by Interacting Proteins and by Ubiquitination; I. Introduction; II. Proline-Rich Regions in ENaC and Their Interacting Proteins; III. Nedd4: Its Domains and Mode of Interaction with ENaC; IV. Regulation of ENaC Stability and Function by Ubiquitination; V. Role of the C2 Domain of Nedd4 in Ca2+-Dependent Membrane Targeting | |
| 505 | 8 | |a VI. SummaryReferences; Chapter 6. Role of G Proteins in the Regulation of Apical Membrane Sodium Permeability by Aldosterone in Epithelia; I. Introduction; II. Control of Basal Na+ Transport by G Proteins; III. GTP-Dependent Methylation of Membrane Proteins; IV. Control of Basal Na+ Permeability by Methylation; V. Aldosterone-Dependent Methylation of Membrane Proteins; VI. Aldosterone-Dependent Membrane GTPase Activity; VII. The Effect of Pertussis Toxin on Membrane Na+ Transport and GTPase Activity; VIII. The Effect of Aldosterone on G-Protein Expression; IX. Conclusion; References | |
| 505 | 8 | |a Chapter 7. The Role of Posttranslational Modifications of Proteins in the Cellular Mechanism of Action of AldosteroneReferences; Chapter 8. Regulation of Amiloride-Sensitive Na+ Channels in the Renal Collecting Duct; I. Introduction; II. Vasopressin Can Act as an Antinatriuretic as Well as an Antidiuretic Hormone; III. Autacoids That Limit the Actions of Aldosterone and Vasopression in the CCD; IV. Trafficking and the Regulation of the Amiloride-Sensitive Na+ Channel; V. A Challenge for Integrative Physiology-The Link between Na+ Retention and Hypertension; References | |
| 546 | |a English. | ||
| 650 | 0 | |a Cell membranes. | |
| 650 | 0 | |a Sodium channels. | |
| 650 | 6 | |a Membrane cellulaire. |0 (CaQQLa)201-0005053 | |
| 650 | 6 | |a Canaux �a sodium. |0 (CaQQLa)201-0156717 | |
| 650 | 7 | |a Cell membranes |2 fast |0 (OCoLC)fst00850194 | |
| 650 | 7 | |a Sodium channels |2 fast |0 (OCoLC)fst01124048 | |
| 700 | 1 | |a Benos, Dale J. | |
| 776 | |z 0-12-153347-6 | ||
| 830 | 0 | |a Current topics in membranes ; |v 47. | |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780121533472 |z Texto completo |