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Advances in cancer research. Volume 78 /
Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here once again, outstanding and original reviews are presented. Key Features * Cell Transformation by the E7 Oncoprotein of HPV Type 16: Interactions with Nuclear and Cytoplasmic Ta...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
San Diego :
Academic Press,
2000.
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| Colección: | Advances in Cancer Research.
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| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Front Cover; Advances in Cancer Research, Volume 78; Copyright Page; Contents; Contributors to Volume 78; Chapter 1. Cell Transformation by the E7 Oncoprotein of Human Papillomavirus Type 16: Interactions with Nuclear and Cytoplasmic Target Proteins; I. Background: The Role of Papillomaviruses in Human Cancer; II. Cellular E7-Binding Proteins; III. Modulation of Cellular Functions by E7; IV. The Role of HPV-16 E7 in Cell Proliferation and Immortalization; References; Chapter 2. Tumor Invasion: Role of Growth Facto-lnduced Cell Motility; I. Introduction; II. Tumor Invasiveness.
- III. Cell MotilityIV. Motility in Tumor Invasion; V. Therapeutic Interventions; VI. Summary and Future Directions; References; Chapter 3. Nonenzymatic Interactions between Proteinases and the Cell Surface: Novel Roles in Normal and Malignant Cell Physiology; I. Introduction; II. Extracellular Matrix-Degrading Proteinases: Classification and Structural Features; III. Proteolysis-Independent Roles of Extracellular Matrix-Degrading Proteinases; IV. Conclusions and Perspectives; References; Chapter 4. Molecular Pathogenesis of AIDS-Associated Kaposi's Sarcoma: Growth and Apoptosis.
- I. IntroductionII. Histopathogenesis; III. Clinical Features; IV. In Vitro and in Vivo Models; V. Molecular Mechanisms of Kaposi's Sarcoma Cell Growth; VI. Roles of Virus Infections in Kaposi's Sarcoma Development; VII. Apoptosis in Kaposi's Sarcoma Cells; VIII. Concluding Remarks and Therapeutic Implications; References; Chapter 5. Perspectives on Cancer Chemoprevention Research and Drug Development; I. Introduction; II. Nature of Carcinogenesis; III. Definition of Chemoprevention and Chemoprevention Agent Discovery; IV. Chemopreventive Agent Development.
- V. Cancer Chemoprevention at Major Cancer Target SitesVI. Surrogate End Points in Defining Chemopreventive Efficacy-Importance of Evaluating Both Phenotypic and Genotypic Effects; VII. Major Issues and Challenges for Cancer Chemoprevention; References; Index.