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Current topics in membranes. Volume 48, Membrane permeability: 100 years since Ernest Overton /
Membrane permeability is fundamental to all cell biology and subcellular biology. The cell exists as a closed unit. Import and export depend upon a number of sophisticated mechanisms, such as active transport, endocytosis, exocytosis, and passive diffusion. These systems are critical for the normal...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
San Diego :
Academic Press,
1999.
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| Colección: | Current topics in membranes ;
48. |
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Front Cover; Membrane Permeability: 100 Years since Ernest Overton; Copyright Page; Contents; Contributors; Tribute; Previous Volumes in Series; Chapter 1. Charles Ernest Overton's Concept of a Cell Membrane; I.A Brief Biography of Ernest Overton; II. The Exchange of Solutes across the Cell Boundary; III. Meyer-Overton Theory of Narcosis; IV. Role of Cations in the Excitability Process; V. Overton's Scientific Personality; References; Chapter 2. Structure and Physical Properties of the Lipid Membrane; I. Bilayers in Biological Membranes; II. Phase Behavior of Membrane Phospholipids
- III. Structure of Phospholipid BilayersIV. Stability and Mechanical Properties of Bilayers; V. Interbilayer Interactions; VI. Roles of Specific Lipids in Membrane Bilayers; VII. Summary; References; Chapter 3. Insights from Computer Simulations into the Interactions of Small Molecules with Lipid Bilayers; I. Introduction; II. Methods of Simulation; III. Distribution of Solutes in a Bilayer; IV. Membrane Permeability of Small Molecules; V. Summary; References; Chapter 4. Membrane Permeability Barriers to Ionic and Polar Solutes; I. Introduction; II. Overton's Concept of Membrane Permeability
- III. Permeation by the Solubility-Diffusion MechanismIV. Permeation through Transient Pores; V. Proton Permeation; VI. Summary; References; Chapter 5. Water Permeation across Membranes; I. Introduction; II. Biophysics of Water Transport; III. Water Transport across Lipid Membranes; IV. Water Transport across Biological Membranes: Water Channels; V. Summary; References; Chapter 6. Membrane Events Involved in Volume Regulation; I. Introduction: Biological Role; II. Membrane Transport Mechanisms in Regulatory Volume Decrease (RVD)
- III. Membrane Transport Systems Involved in Volume Regulatory Increase (RVI)IV. Volume Sensing and Signal Transduction; V. Cytoskeleton and Cell Volume Regulation; VI. Summary; References; Chapter 7. Interaction of Natural and Model Peptides with Membranes; I. Introduction; II. Free Energy of Peptide Binding to Membranes; III. Factors Influencing Peptide Structure and Orientation in Membranes; IV. Summary; References; Chapter 8. Lateral Diffusion of Lipids and Proteins; I. Introduction; II. The Key Question; III. Theoretical Developments; IV. Factors Controlling Lateral Diffusion
- v. Applications to MembranesVI. Summary; References; Chapter 9. A Short History of Ion Channels and Signal Propagation; I. Introduction; II. Ionic Currents in Axons; III. Carriers, Pores, Gates, and Selectivity before Cloning; IV. The Age of Cloning; V. Summary; References; Chapter 10. Lipid Membrane and Ligand-Gated Ion Channels in General Anesthetic Action; I. Introduction; II. The Meyer-Overton Hypothesis and the Evolution of Lipid-Based Theories of Anesthesia; III. The Rise of Protein-Based Theories of Anesthetic Action; IV. Future Directions; V. Summary; References