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Current topics in membranes. Volume 48, Membrane permeability: 100 years since Ernest Overton /
Membrane permeability is fundamental to all cell biology and subcellular biology. The cell exists as a closed unit. Import and export depend upon a number of sophisticated mechanisms, such as active transport, endocytosis, exocytosis, and passive diffusion. These systems are critical for the normal...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
San Diego :
Academic Press,
1999.
|
| Colección: | Current topics in membranes ;
48. |
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 245 | 0 | 0 | |a Current topics in membranes. |n Volume 48, |p Membrane permeability: 100 years since Ernest Overton / |c edited by David W. Deamer, Arnost Kleinzeller, Douglas M. Fambrough. |
| 260 | |a San Diego : |b Academic Press, |c 1999. | ||
| 300 | |a 1 online resource (xviii, 423 pages) : |b illustrations. | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 490 | 1 | |a Current topics in membranes ; |v 48 | |
| 504 | |a Includes bibliographical references and index. | ||
| 588 | 0 | |a Print version record. | |
| 520 | |a Membrane permeability is fundamental to all cell biology and subcellular biology. The cell exists as a closed unit. Import and export depend upon a number of sophisticated mechanisms, such as active transport, endocytosis, exocytosis, and passive diffusion. These systems are critical for the normal housekeeping physiological functions. However, access to the cell is also taken advantage of by toxic microbes (such as cholera or ptomaine) and when designing drugs. Ernest Overton, one of the pioneers in lipid membrane research, put forward the first comprehensive theory of lipid membrane structure. His most quoted paper on the osmotic properties of cells laid the foundation for the modern concepts of membrane function, most notably important in anesthesia. This book is designed to celebrate the centennial anniversary (in the first chapter) of Overton's work. Subsequent chapters present readers with up-to-date concepts of membrane structure and function and the challenge they pose for new explorations. Key Features * Provides an historical perspective of Overton's contributions to the theory of narcosis * Presents an overview of each permeability mechanism, including active transport, endocytosis, exocytosis, and passive diffusion. | ||
| 505 | 0 | |a Front Cover; Membrane Permeability: 100 Years since Ernest Overton; Copyright Page; Contents; Contributors; Tribute; Previous Volumes in Series; Chapter 1. Charles Ernest Overton's Concept of a Cell Membrane; I.A Brief Biography of Ernest Overton; II. The Exchange of Solutes across the Cell Boundary; III. Meyer-Overton Theory of Narcosis; IV. Role of Cations in the Excitability Process; V. Overton's Scientific Personality; References; Chapter 2. Structure and Physical Properties of the Lipid Membrane; I. Bilayers in Biological Membranes; II. Phase Behavior of Membrane Phospholipids | |
| 505 | 8 | |a III. Structure of Phospholipid BilayersIV. Stability and Mechanical Properties of Bilayers; V. Interbilayer Interactions; VI. Roles of Specific Lipids in Membrane Bilayers; VII. Summary; References; Chapter 3. Insights from Computer Simulations into the Interactions of Small Molecules with Lipid Bilayers; I. Introduction; II. Methods of Simulation; III. Distribution of Solutes in a Bilayer; IV. Membrane Permeability of Small Molecules; V. Summary; References; Chapter 4. Membrane Permeability Barriers to Ionic and Polar Solutes; I. Introduction; II. Overton's Concept of Membrane Permeability | |
| 505 | 8 | |a III. Permeation by the Solubility-Diffusion MechanismIV. Permeation through Transient Pores; V. Proton Permeation; VI. Summary; References; Chapter 5. Water Permeation across Membranes; I. Introduction; II. Biophysics of Water Transport; III. Water Transport across Lipid Membranes; IV. Water Transport across Biological Membranes: Water Channels; V. Summary; References; Chapter 6. Membrane Events Involved in Volume Regulation; I. Introduction: Biological Role; II. Membrane Transport Mechanisms in Regulatory Volume Decrease (RVD) | |
| 505 | 8 | |a III. Membrane Transport Systems Involved in Volume Regulatory Increase (RVI)IV. Volume Sensing and Signal Transduction; V. Cytoskeleton and Cell Volume Regulation; VI. Summary; References; Chapter 7. Interaction of Natural and Model Peptides with Membranes; I. Introduction; II. Free Energy of Peptide Binding to Membranes; III. Factors Influencing Peptide Structure and Orientation in Membranes; IV. Summary; References; Chapter 8. Lateral Diffusion of Lipids and Proteins; I. Introduction; II. The Key Question; III. Theoretical Developments; IV. Factors Controlling Lateral Diffusion | |
| 505 | 8 | |a v. Applications to MembranesVI. Summary; References; Chapter 9. A Short History of Ion Channels and Signal Propagation; I. Introduction; II. Ionic Currents in Axons; III. Carriers, Pores, Gates, and Selectivity before Cloning; IV. The Age of Cloning; V. Summary; References; Chapter 10. Lipid Membrane and Ligand-Gated Ion Channels in General Anesthetic Action; I. Introduction; II. The Meyer-Overton Hypothesis and the Evolution of Lipid-Based Theories of Anesthesia; III. The Rise of Protein-Based Theories of Anesthetic Action; IV. Future Directions; V. Summary; References | |
| 546 | |a English. | ||
| 650 | 0 | |a Membrane lipids. | |
| 650 | 0 | |a Membranes (Biology) |x Permeability. | |
| 650 | 6 | |a Lipides membranaires. |0 (CaQQLa)201-0220895 | |
| 650 | 6 | |a Membranes (Biologie) |0 (CaQQLa)201-0009733 |x Perm�eabilit�e. |0 (CaQQLa)201-0380198 | |
| 650 | 7 | |a Membrane lipids. |2 fast |0 (OCoLC)fst01015844 | |
| 650 | 7 | |a Membranes (Biology) |x Permeability. |2 fast |0 (OCoLC)fst01015866 | |
| 700 | 1 | |a Deamer, D. W. | |
| 700 | 1 | |a Kleinzeller, Arno�st. | |
| 700 | 1 | |a Fambrough, Douglas M. | |
| 776 | 0 | |z 0121533484 | |
| 830 | 0 | |a Current topics in membranes ; |v 48. | |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780121533489 |z Texto completo |