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Molecular mechanisms of immunological self-recognition /
Molecular Mechanisms of Immunological Self-Recognition covers the understanding of immunological self-recognition. The introductory chapter of the book summarizes the dawn of the insight into immunological tolerance, and provides an overview of research on the underlying mechanisms. The book address...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
San Diego :
Academic Press,
�1993.
|
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 245 | 0 | 0 | |a Molecular mechanisms of immunological self-recognition / |c edited by Frederick W. Alt, Henry J. Vogel. |
| 260 | |a San Diego : |b Academic Press, |c �1993. | ||
| 300 | |a 1 online resource (xiv, 259 pages) : |b illustrations | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 504 | |a Includes bibliographical references and index. | ||
| 505 | 0 | |a Immunological tolerance revisited in the molecular era / G.J.V. Nossal -- Mechanisms and meaning of B lymphocyte tolerance / David Nemazee -- Tolerant autoreactive B lymphocytes in the follicular mantle zone compartment: substrates for receptor editing and reform / Christopher G. Goodnow [and others] -- T cell anergy / Bart Beverly [and others] -- T cell antigen receptor: biochemical aspects of signal transduction / Lawrence E. Samelson [and others] -- Structure and signaling function of B cell antigen receptors of different classes / Michael Reth [and others] -- Self-nonself discrimination by T lymphocytes / Harald Von Boehmer and Benedita Rocha -- Transgenic mouse model of lymphocyte development / Dennis Y. Loh -- Recognition requirements for the positive selection of the T cell repertoire: a role of self-peptides and major histocompatibility complex pockets / Janko Nikolic-Zugic and Michael J. Bevan -- Mechanisms of peripheral tolerance / Gunter J. Hammerling [and others]. | |
| 505 | 0 | |a (cont) Analysis of T cell receptor-ligand interaction using a transgenic antigen model for T cell tolerance and T cell receptor mutagenesis / Barbara Fazekas De St. Groth -- T cell repertoire and tolerance / Ann M. Pullen [and others] -- Sequential occurrence of positive and negative selection during T lymphocyte maturation / Cynthia J. Guidos and Irving L. Weissman -- Tolerance induction in the peripheral immune system / Matt Wise [and others] -- Activation-induced cell death of effector T cells: a third mechanism of immune tolerance / Charles A. Janeway, Jr. and Yang Liu -- T cells involved in inductive events in the pathogenesis of autoimmune diabetes mellitus / C. Garrison Fathman [and others] -- Genetic control of diabetes and insulitis in the nonobese diabetic mouse: analysis of the NOD. H-2b and B10.H-2mod strains / Linda S. Wicker [and others] -- Islet tolerance in humans and transgenic mice / Nora Sarvetnick -- Fluorescence-activated cell sorter analysis of peptide-major histocompatibility complex / Animesh A. Sinha [and others]. | |
| 505 | 0 | |a (cont) Tolerance to self: a delicate balance / Ellen Heber-Katz -- Prevention, suppression, and treatment of experimental autoimmune encephalomyelitis with a synthetic T cell receptor V region peptide / Halina Offner [and others] -- Tolerance of self: present and future / N.A. Mitchison. | |
| 506 | |3 Use copy |f Restrictions unspecified |2 star |5 MiAaHDL | ||
| 533 | |a Electronic reproduction. |b [Place of publication not identified] : |c HathiTrust Digital Library, |d 2010. |5 MiAaHDL | ||
| 538 | |a Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. |u http://purl.oclc.org/DLF/benchrepro0212 |5 MiAaHDL | ||
| 583 | 1 | |a digitized |c 2010 |h HathiTrust Digital Library |l committed to preserve |2 pda |5 MiAaHDL | |
| 588 | 0 | |a Print version record. | |
| 520 | |a Molecular Mechanisms of Immunological Self-Recognition covers the understanding of immunological self-recognition. The introductory chapter of the book summarizes the dawn of the insight into immunological tolerance, and provides an overview of research on the underlying mechanisms. The book addresses the developments in the molecular mechanisms of B and T cell tolerance and describes the failure of tolerance in autoimmunity. The text concludes by furnishing orienting perspectives and highlighting new information presented. The novel findings characterized as impressive advances pertain to the areas of B cell development and the generation of molecular diversity; V gene usage, especially from transgenes, in positive and negative thymic selection; the handling of positive and negative signals by T and B cells; anergy in postthymic T cells; the design of peptide-based therapy for autoimmune diseases; and the design of therapy with the aid of monoclonal antibodies. Immunologists will find the text useful. | ||
| 650 | 0 | |a Immunological tolerance. | |
| 650 | 0 | |a Cellular recognition. | |
| 650 | 0 | |a T cells. | |
| 650 | 0 | |a B cells. | |
| 650 | 0 | |a Autoimmunity. | |
| 650 | 0 | |a Cell interaction. | |
| 650 | 2 | |a Autoimmunity |0 (DNLM)D015551 | |
| 650 | 2 | |a B-Lymphocytes |x immunology |0 (DNLM)D001402Q000276 | |
| 650 | 2 | |a Cell Communication |0 (DNLM)D002450 | |
| 650 | 2 | |a Immune Tolerance |0 (DNLM)D007108 | |
| 650 | 2 | |a T-Lymphocytes |x immunology |0 (DNLM)D013601Q000276 | |
| 650 | 2 | |a B-Lymphocytes |0 (DNLM)D001402 | |
| 650 | 6 | |a Tol�erance immunitaire. |0 (CaQQLa)201-0013203 | |
| 650 | 6 | |a Reconnaissance cellulaire. |0 (CaQQLa)201-0075516 | |
| 650 | 6 | |a Lymphocytes B. |0 (CaQQLa)201-0056955 | |
| 650 | 6 | |a Auto-immunit�e. |0 (CaQQLa)201-0060759 | |
| 650 | 6 | |a Cellules |x Interaction. |0 (CaQQLa)201-0005047 | |
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| 650 | 7 | |a Autoimmunity |2 fast |0 (OCoLC)fst00822674 | |
| 650 | 7 | |a B cells |2 fast |0 (OCoLC)fst00824789 | |
| 650 | 7 | |a Cellular recognition |2 fast |0 (OCoLC)fst00850286 | |
| 650 | 7 | |a Immunological tolerance |2 fast |0 (OCoLC)fst00968002 | |
| 650 | 7 | |a T cells |2 fast |0 (OCoLC)fst01141544 | |
| 650 | 7 | |a Immuntoleranz |2 gnd |0 (DE-588)4161391-0 | |
| 650 | 1 | 7 | |a Auto-immuniteit. |2 gtt |
| 650 | 1 | 7 | |a Lymfocyten. |2 gtt |
| 650 | 1 | 7 | |a Immuunreacties. |2 gtt |
| 653 | 0 | |a Humans |a Immune system | |
| 655 | 0 | |a Congresses | |
| 655 | 2 | |a Congress |0 (DNLM)D016423 | |
| 655 | 7 | |a proceedings (reports) |2 aat |0 (CStmoGRI)aatgf300027316 | |
| 655 | 7 | |a Conference papers and proceedings |2 fast |0 (OCoLC)fst01423772 | |
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| 655 | 7 | |a Actes de congr�es. |2 rvmgf |0 (CaQQLa)RVMGF-000001049 | |
| 700 | 1 | |a Alt, Frederick W. | |
| 700 | 1 | |a Vogel, Henry J. |q (Henry James), |d 1920-2007. | |
| 776 | 0 | 8 | |i Print version: |t Molecular mechanisms of immunological self-recognition. |d San Diego : Academic Press, �1993 |w (DLC) 92049201 |w (OCoLC)26396546 |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780120537501 |z Texto completo |