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100630s1982 ctua ob 001 0 eng d |
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|a OCLCE
|b eng
|e pn
|c OCLCE
|d OCLCQ
|d OCLCO
|d UIU
|d OCLCQ
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|d OCLCQ
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|a 607763100
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|a 9781483193410
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|z 0723605890
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|z 9780723605898
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|a (OCoLC)644932132
|z (OCoLC)607763100
|z (OCoLC)974618226
|z (OCoLC)987744231
|z (OCoLC)988561833
|z (OCoLC)1036808828
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|a dlr
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|a QP801.H5
|b P42 1982
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|a QV 157
|b P536 1982
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|a 612/.0157
|2 19
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|a Pharmacology of histamine receptors /
|c edited by C.R. Ganellin, M.E. Parsons ; with a foreword by Sir William Paton.
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260 |
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|a Bristol ;
|a Boston :
|b PSG,
|c 1982.
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300 |
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|a 1 online resource (xvii, 521 pages) :
|b illustrations
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336 |
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|a online resource
|b cr
|2 rdacarrier
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504 |
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|a Includes bibliographical references and index.
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506 |
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|3 Use copy
|f Restrictions unspecified
|2 star
|5 MiAaHDL
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533 |
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|a Electronic reproduction.
|b [Place of publication not identified] :
|c HathiTrust Digital Library,
|d 2010.
|5 MiAaHDL
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538 |
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|a Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.
|u http://purl.oclc.org/DLF/benchrepro0212
|5 MiAaHDL
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|a digitized
|c 2010
|h HathiTrust Digital Library
|l committed to preserve
|2 pda
|5 MiAaHDL
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|a Print version record.
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|a Front Cover; Pharmacology of Histamine Receptors; Copyright Page; Preface; List of Contributors; Table of Contents; List of Abbreviations; Foreword; Chapter One. Reflections on the Classification of Histamine Receptors; Mepyramine and Related Histamine Antagonists; Cimetidine and Related Antagonists; References; Chapter Two. Chemistry and Structure-Activity Relationships of Drugs Acting at Histamine Receptors; 1. Chemical Constitution of Histamine; 2. Homogeneous Series of Compounds for Structure-Activity studies as Histamine Receptor Agonists
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|a 3. Evidence for the Active Form of Histamine at H1- and H2-receptors4. Amidines as H2-receptor Agonists; 5. Selective Agonists and Chemical Control Substances for use in Pharmacological Characterisation of Histamine Receptors; 6. H1-receptor Histamine Antagonists (Antihistamines); 7. H2-receptor Histamine Antagonists; References; Chapter Three. Factors Regulating Availability of Histamine at Tissue Receptors; 1. Introduction; 2. Histamine Levels in Tissues and Body Fluids; 3. Histamine Synthesis and Metabolism; 4. Cellular Sources of Histamine in Tissues and Blood
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|a 5. Estimation of Histamine Synthesis and Turnover in the Intact Tissues6. What are Physiological Concentrations of Histamine?; References; Chapter Four. Histamine Receptors and Cyclic Nucleotides; 1. Basic Properties of Adenylate Cyclase and its Measurement; 2. Membrane Structure and the Floating Receptor Model; 3. Role of Guanylnucleotides in Receptor-Cyclase Coupling; 4. The Role of Membrane Lipids in Receptor-Cyclase Coupling; Relationship between Histamine-activated Adenylate Cyclase and the Physiological Effects of H2-Receptor Activation; Acknowledgements; References
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|a Chapter Five. Histamine Receptors and Gastric Secretion1. The Histamine Locale; 2. The H2-receptor of the Parietal Cell and Adenylate Cyclase; 3. The Unitarian Histamine Hypothesis put to Test; 4. Continuation of the Histamine Hypothesis; Acknowledgement; References; Chapter Six. Actions of Histamine on the Heart and Vasculature; 1. Cardiovascular Actions of Histamine; 2. Effects of Histamine on Functional Parameters of the Mammalian Heart; 3. Haemodynamic Effects of Histamine; 4. Physiological Significance of Histamine in the Cardiovascular System
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|a 5. Pathological Significance of Histamine in the Cardiovascular System6. Conclusions; Acknowledgements; References; Chapter Seven. Histamine Receptor Mechanisms of the Lung; 1. Introduction; 2. Pulmonary Vasculature; 3. Bronchial Vasculature; 4. Airway Smooth Muscle; 5. Secretory and Mucociliary Activity; 6. Immunopharmacological Modulation of Pulmonary Hypersensitivity and Inflammation; References; Chapter Eight. Histamine Receptors in Alimentary and Genito-urinary Smooth Muscle; 1. Introduction; 2. The Alimentary Tract; 3. The Ureter and Bladder; 4. The Gall Bladder; 5. The Uterus
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|a Pharmacology of Histamine Receptors presents a summary of the pharmacology of histamine receptors. It discusses the research and developments made in the use of histamine. It addresses the biological actions of the drug in various pathological instances. Some of the topics covered in the book are the classification of histamine receptors; mepyramine and related histamine antagonists; activity relationships of drugs acting at histamine receptors; chemical structure of histamine; effects of methyl substituents in histamine; enzymes involved in histamine metabolism; and histamine in body fluids.
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|a English.
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650 |
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|a Histamine
|x Physiological effect.
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650 |
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0 |
|a Histamine
|x Receptors.
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650 |
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0 |
|a Antihistamines.
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650 |
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2 |
|a Receptors, Histamine
|x physiology
|0 (DNLM)D011968Q000502
|
650 |
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2 |
|a Receptors, Histamine
|0 (DNLM)D011968
|
650 |
|
2 |
|a Histamine Antagonists
|0 (DNLM)D006633
|
650 |
|
6 |
|a Histamine
|0 (CaQQLa)201-0020084
|x Effets physiologiques.
|0 (CaQQLa)201-0374337
|
650 |
|
6 |
|a Histamine
|x R�ecepteurs.
|0 (CaQQLa)201-0092761
|
650 |
|
6 |
|a Antihistaminiques.
|0 (CaQQLa)201-0020083
|
650 |
|
7 |
|a Antihistamines.
|2 fast
|0 (OCoLC)fst00810540
|
650 |
|
7 |
|a Histamine
|x Physiological effect.
|2 fast
|0 (OCoLC)fst00957650
|
650 |
|
7 |
|a Histamine
|x Receptors.
|2 fast
|0 (OCoLC)fst00957651
|
650 |
|
7 |
|a R�ecepteurs histaminergiques
|x Pharmacologie.
|2 fmesh
|
653 |
|
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|a Man. Histamine receptors.
|
700 |
1 |
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|a Ganellin, C. R.
|q (C. Robin)
|
700 |
1 |
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|a Parsons, M. E.
|q (Michael E.)
|
776 |
0 |
8 |
|i Print version:
|t Pharmacology of histamine receptors.
|d Bristol ; Boston : PSG, 1982
|w (DLC) 81071440
|w (OCoLC)9081526
|
856 |
4 |
0 |
|u https://sciencedirect.uam.elogim.com/science/book/9780723605898
|z Texto completo
|