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Pharmacology of histamine receptors /

Pharmacology of Histamine Receptors presents a summary of the pharmacology of histamine receptors. It discusses the research and developments made in the use of histamine. It addresses the biological actions of the drug in various pathological instances. Some of the topics covered in the book are th...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Ganellin, C. R. (C. Robin), Parsons, M. E. (Michael E.)
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Bristol ; Boston : PSG, 1982.
Temas:
Acceso en línea:Texto completo

MARC

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245 0 0 |a Pharmacology of histamine receptors /  |c edited by C.R. Ganellin, M.E. Parsons ; with a foreword by Sir William Paton. 
260 |a Bristol ;  |a Boston :  |b PSG,  |c 1982. 
300 |a 1 online resource (xvii, 521 pages) :  |b illustrations 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
504 |a Includes bibliographical references and index. 
506 |3 Use copy  |f Restrictions unspecified  |2 star  |5 MiAaHDL 
533 |a Electronic reproduction.  |b [Place of publication not identified] :  |c HathiTrust Digital Library,  |d 2010.  |5 MiAaHDL 
538 |a Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.  |u http://purl.oclc.org/DLF/benchrepro0212  |5 MiAaHDL 
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588 0 |a Print version record. 
505 0 |a Front Cover; Pharmacology of Histamine Receptors; Copyright Page; Preface; List of Contributors; Table of Contents; List of Abbreviations; Foreword; Chapter One. Reflections on the Classification of Histamine Receptors; Mepyramine and Related Histamine Antagonists; Cimetidine and Related Antagonists; References; Chapter Two. Chemistry and Structure-Activity Relationships of Drugs Acting at Histamine Receptors; 1. Chemical Constitution of Histamine; 2. Homogeneous Series of Compounds for Structure-Activity studies as Histamine Receptor Agonists 
505 8 |a 3. Evidence for the Active Form of Histamine at H1- and H2-receptors4. Amidines as H2-receptor Agonists; 5. Selective Agonists and Chemical Control Substances for use in Pharmacological Characterisation of Histamine Receptors; 6. H1-receptor Histamine Antagonists (Antihistamines); 7. H2-receptor Histamine Antagonists; References; Chapter Three. Factors Regulating Availability of Histamine at Tissue Receptors; 1. Introduction; 2. Histamine Levels in Tissues and Body Fluids; 3. Histamine Synthesis and Metabolism; 4. Cellular Sources of Histamine in Tissues and Blood 
505 8 |a 5. Estimation of Histamine Synthesis and Turnover in the Intact Tissues6. What are Physiological Concentrations of Histamine?; References; Chapter Four. Histamine Receptors and Cyclic Nucleotides; 1. Basic Properties of Adenylate Cyclase and its Measurement; 2. Membrane Structure and the Floating Receptor Model; 3. Role of Guanylnucleotides in Receptor-Cyclase Coupling; 4. The Role of Membrane Lipids in Receptor-Cyclase Coupling; Relationship between Histamine-activated Adenylate Cyclase and the Physiological Effects of H2-Receptor Activation; Acknowledgements; References 
505 8 |a Chapter Five. Histamine Receptors and Gastric Secretion1. The Histamine Locale; 2. The H2-receptor of the Parietal Cell and Adenylate Cyclase; 3. The Unitarian Histamine Hypothesis put to Test; 4. Continuation of the Histamine Hypothesis; Acknowledgement; References; Chapter Six. Actions of Histamine on the Heart and Vasculature; 1. Cardiovascular Actions of Histamine; 2. Effects of Histamine on Functional Parameters of the Mammalian Heart; 3. Haemodynamic Effects of Histamine; 4. Physiological Significance of Histamine in the Cardiovascular System 
505 8 |a 5. Pathological Significance of Histamine in the Cardiovascular System6. Conclusions; Acknowledgements; References; Chapter Seven. Histamine Receptor Mechanisms of the Lung; 1. Introduction; 2. Pulmonary Vasculature; 3. Bronchial Vasculature; 4. Airway Smooth Muscle; 5. Secretory and Mucociliary Activity; 6. Immunopharmacological Modulation of Pulmonary Hypersensitivity and Inflammation; References; Chapter Eight. Histamine Receptors in Alimentary and Genito-urinary Smooth Muscle; 1. Introduction; 2. The Alimentary Tract; 3. The Ureter and Bladder; 4. The Gall Bladder; 5. The Uterus 
520 |a Pharmacology of Histamine Receptors presents a summary of the pharmacology of histamine receptors. It discusses the research and developments made in the use of histamine. It addresses the biological actions of the drug in various pathological instances. Some of the topics covered in the book are the classification of histamine receptors; mepyramine and related histamine antagonists; activity relationships of drugs acting at histamine receptors; chemical structure of histamine; effects of methyl substituents in histamine; enzymes involved in histamine metabolism; and histamine in body fluids. 
546 |a English. 
650 0 |a Histamine  |x Physiological effect. 
650 0 |a Histamine  |x Receptors. 
650 0 |a Antihistamines. 
650 2 |a Receptors, Histamine  |x physiology  |0 (DNLM)D011968Q000502 
650 2 |a Receptors, Histamine  |0 (DNLM)D011968 
650 2 |a Histamine Antagonists  |0 (DNLM)D006633 
650 6 |a Histamine  |0 (CaQQLa)201-0020084  |x Effets physiologiques.  |0 (CaQQLa)201-0374337 
650 6 |a Histamine  |x R�ecepteurs.  |0 (CaQQLa)201-0092761 
650 6 |a Antihistaminiques.  |0 (CaQQLa)201-0020083 
650 7 |a Antihistamines.  |2 fast  |0 (OCoLC)fst00810540 
650 7 |a Histamine  |x Physiological effect.  |2 fast  |0 (OCoLC)fst00957650 
650 7 |a Histamine  |x Receptors.  |2 fast  |0 (OCoLC)fst00957651 
650 7 |a R�ecepteurs histaminergiques  |x Pharmacologie.  |2 fmesh 
653 |a Man. Histamine receptors. 
700 1 |a Ganellin, C. R.  |q (C. Robin) 
700 1 |a Parsons, M. E.  |q (Michael E.) 
776 0 8 |i Print version:  |t Pharmacology of histamine receptors.  |d Bristol ; Boston : PSG, 1982  |w (DLC) 81071440  |w (OCoLC)9081526 
856 4 0 |u https://sciencedirect.uam.elogim.com/science/book/9780723605898  |z Texto completo