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Tissue remodeling and epithelial morphogenesis /
For more than thirty years, Current Topics in Developmental Biology has provided a forum for dissemination and discussion of new ideas and thought in developmental biology. Bringing together a series of articles on the structural, functional, and developmental characteristics of epithelial, this the...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
London :
Academic Press,
2009.
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| Colección: | Current topics in developmental biology ;
89 |
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Front Cover; Current Topics in Developmental Biology; Copyright Page; Contents; Contributors; Preface; Chapter 1: Intercellular Adhesion in Morphogenesis: Molecular and Biophysical Considerations; 1. Introduction; 2. Molecular Basis of Intercellular Adhesion; 2.1. Formation of trans-binding interactionsby classical cadherins; 2.2. Intracellular signaling by cadherins; 2.3. Cytoskeletal responses; 2.4. Cell interfacial tension response and the rise of adhesion energy; 3. Modulation of Intercellular Adhesion in Development; 3.1. Modulation of cadherin-catenin membrane levels
- 3.2. Modulation of cortical cytoskeleton organization and response3.3. Differential expression of cadherin subtypes; 4. Intercellular Adhesion Energy and Morphogenesis; 4.1. Intercellular adhesion energy and tissue surface tension; 4.2. Cell sorting and tissue envelopment; 4.3. Origins of heterotypic adhesion energy; 4.4. Cadherin expression levels versus cytoskeleton remodeling; 4.5. Intercellular adhesion energy and polarity; 4.6. Cell interfacial tension refinements; 4.7. Loss of tissue liquid-like behavior; 4.8. Dynamics; 5. Conclusions; Acknowledgments; References
- Chapter 2: Remodeling of the Adherens Junctions During Morphogenesis1. Introduction; 2. Basic Machinery of the Adherens Junction; 3. Remodeling by Small GTPase; 4. Remodeling by Cadherin Turnover and Endocytosis; 4.1. Basic processes of cadherin recycling; 4.2. p120-catenin-dependent cadherin stabilization; 4.3. MicroRNA-dependent turnover; 4.4. Other mechanisms; 5. Remodeling by Nonclassic Cadherins and Nectins; 5.1. Protocadherins; 5.2. Fat cadherins; 5.3. Nectins; 6. Junctional Remodeling During Morphogenesis; 6.1. Remodeling through actin modulation
- 6.2. Cadherin endocytosis during epithelial cell packing6.3. Classic cadherin regulation during gastrulation and neurulation; 7. Perspectives; Acknowledgments; References; Chapter 3: How the Cytoskeleton Helps Build the Embryonic Body Plan: Models of Morphogenesis from Drosophila; 1. Introduction; 2. Establishing Epithelial Structure; 2.1. Forming the first epithelial cells of the Drosophila embryo; 2.2. Connecting cells by assembling adherens junctions; 3. Epithelial Morphogenesis; 3.1. Internalizing mesoderm: Actomyosincontractility drives apical constriction
- 3.2. Germband extension: Actomyosin contractility driving cell intercalation3.3. Microtubule arrays contributing to gastrulation; 3.4. Dorsal closure: Integrating signaling, the cytoskeleton, and adhesion to drive epithelialsheet migration and sealing; 3.5. Adding complexity to the JNK and Dpp pathways; 3.6. An embarrassment of riches: Five nonreceptor tyrosine kinases regulate dorsal closure; 3.7. Roles for novel regulators of adhesionand the cytoskeleton; 3.8. Powering closure by old and new mechanisms; 3.9. Reaching out to close the gap-Key roles for cellprotrusions in dorsal closure