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Transgenesis and targeted mutagenesis in immunology /

Investigations into the field of immunology are rapidly expanding with the use of genetically altered mice at the embryonic stage. This breakthrough laboratory guide provides a complete study of transgenesis and targeted mutagenesis in laboratory mice that will be valued by researchers looking for f...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Bluethmann, Horst, Ohashi, Pamela S.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: San Diego : Academic Press, �1994.
Temas:
Acceso en línea:Texto completo

MARC

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245 0 0 |a Transgenesis and targeted mutagenesis in immunology /  |c edited by Horst Bluethmann, Pamela S. Ohashi. 
260 |a San Diego :  |b Academic Press,  |c �1994. 
300 |a 1 online resource (xx, 316 pages) :  |b illustrations 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
504 |a Includes bibliographical references and index. 
505 0 |a Transgenic mouse models to study VDJ recombination -- Lymphocyte development and function in T cell receptor and RAG-1 mutant mice -- RAG-2 deficient blastocyst complementation -- Role of CD4 and CD8 in determining cell fate in the thymus -- T cell development in CD4, CD8 and p56 gene-targeted mice -- T cell tolerance in T cell receptor transgenic ipr/ipr mice -- Thymocyte selection and peripheral tolerance using the lymphocyte choriomeningitis virus as a model antigen -- Peripheral T cell tolerance: distinct levels and multistep mechanisms. 
505 0 |a Peripheral tolerance and CD4 T cells -- Studies of tolerance, inflammation and autoimmunity in transgenic mice -- Immunological studies utilizing cytokine transgenic mice -- Effect of MHC class II encoding transgenes on autoimmunity in nonobese diabetic mice -- Development and function of the immune system in mice with targeted disruption of the interleukin 2 gene -- Immune responses in interleukin 4-deficient mice -- Manipulation of transgene-encoded self-antigens to explore mechanisms of B cell tolerance -- Transgenic mouse model for peripheral B cell tolerance. 
505 0 |a Immunobiology of MHC class I-deficient mice -- MHC class II mutant mice. 
506 |3 Use copy  |f Restrictions unspecified  |2 star  |5 MiAaHDL 
533 |a Electronic reproduction.  |b [Place of publication not identified] :  |c HathiTrust Digital Library,  |d 2010.  |5 MiAaHDL 
538 |a Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.  |u http://purl.oclc.org/DLF/benchrepro0212  |5 MiAaHDL 
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588 0 |a Print version record. 
520 |a Investigations into the field of immunology are rapidly expanding with the use of genetically altered mice at the embryonic stage. This breakthrough laboratory guide provides a complete study of transgenesis and targeted mutagenesis in laboratory mice that will be valued by researchers looking for fresh observations and interpretations when designing future experiments. 
650 0 |a Transgenic mice. 
650 0 |a Mice  |x Immunology. 
650 0 |a Immunology  |x Animal models. 
650 0 |a Diseases  |x Animal models. 
650 0 |a Immune system. 
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650 2 |a Disease Models, Animal  |0 (DNLM)D004195 
650 2 |a Immune System  |0 (DNLM)D007107 
650 2 |a Mutagenesis, Site-Directed  |0 (DNLM)D016297 
650 2 |a Mice, Transgenic  |0 (DNLM)D008822 
650 2 |a Immune System Phenomena  |0 (DNLM)D055633 
650 6 |a Souris transg�eniques.  |0 (CaQQLa)201-0207066 
650 6 |a Souris  |0 (CaQQLa)201-0021694  |x Immunologie.  |0 (CaQQLa)201-0380076 
650 6 |a Immunologie  |x Mod�eles animaux.  |0 (CaQQLa)201-0258364 
650 6 |a Maladies  |x Mod�eles animaux.  |0 (CaQQLa)201-0067878 
650 6 |a Syst�eme immunitaire.  |0 (CaQQLa)201-0005078 
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653 0 |a Mice 
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700 1 |a Bluethmann, Horst. 
700 1 |a Ohashi, Pamela S. 
776 0 8 |i Print version:  |t Transgenesis and targeted mutagenesis in immunology.  |d San Diego : Academic Press, �1994  |w (DLC) 93043197  |w (OCoLC)29361189 
856 4 0 |u https://sciencedirect.uam.elogim.com/science/book/9780121057602  |z Texto completo