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Mitochondrial dysfunction /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Lash, Lawrence H., Jones, Dean P., 1949-
Formato: Electrónico eBook
Idioma:Inglés
Publicado: San Diego : Academic Press, �1993.
Colección:Methods in toxicology ; v. 2.
Temas:
Acceso en línea:Texto completo

MARC

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245 0 0 |a Mitochondrial dysfunction /  |c edited by Lawrence H. Lash, Dean P. Jones. 
260 |a San Diego :  |b Academic Press,  |c �1993. 
300 |a 1 online resource (xx, 502 pages, 1 unnumbered pages of plates) :  |b illustrations 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
490 1 |a Methods in toxicology,  |x 1063-3677 ;  |v v. 2 
504 |a Includes bibliographical references and index. 
505 0 |a Introduction: criteria for assessing normal and abnormal mitochondrial function -- Systems for study of mitochondrial dysfunction -- Mitochondrial isolation from liver and kidney: strategy, techniques, and criteria for purity -- Mitochondrial isolation from brain: strategy, techniques, and criteria for purity -- Intact rat brain mitochondria from a single animal: preparation and properties -- Study of skeletal muscle mitochondrial dysfunction -- Small-scale preparation of skeletal muscle mitochondria and its application in the study of human disease -- Metabolic control analysis as a method to assess mitochondrial dysfunction -- Assessment of mitochondrial dysfunction in vivo and in organ systems -- Commentary: methods for in vivo assessment of mitochondrial function -- Noninvasive assessment of mitochondrial function by breath analysis using ketoisocaproic acid -- Absorption spectroscopy for assessment of mitochondrial function in vivo -- Analysis of mitochondrial function by carbon-13 nuclear magnetic resonance spectroscopy in intact tissues. 
505 0 |a (cont) Phosphorus-31 nuclear magnetic resonance spectroscopy in the study of mitochondrial metabolism -- Mitochondrial dysfunction in ischemic organs -- Screening for mitochondrial cytopathy: the subanaerobic threshold exercise test -- Assay of mitochondrial structural integrity -- Morphometry of mitochondria: size, internal structure, subcellular distribution, and three-dimensional reconstruction -- Megamitochondria -- Redox status and mitochondrial inner membrane permeability -- Mitochondrial metabolism and bioactivation and detoxification systems -- Assessment of mitochondrial glutathione as a measure of cell injury -- Experimental manipulation of mitochondrial glutathione concentrations -- Determination of flux, activity, and activity state of mitochondrial [alpha]-keto acid dehydrogenase complexes -- Regulation of oxygen uptake in the liver lobule by oxygen tension -- Generation of reactive oxygen metabolites and oxidative damage in mitochondria: role of calcium. 
505 0 |a (cont) Fatty acid metabolism and Reye's syndrome -- Antioxidative function of vitamin E and ubiquinols -- Mitochondrial NADPH -- Long-chain acyl-CoA metabolism by mitochondrial carnitine palmitoyltransferase: a cell model for pathological studies -- Mitochondrial energetics and transport processes -- Identification of mitochondrial dysfunction at coupling site I: loss of activity of NADH-ubiquinone oxidoreductase during myocardial ischemia -- Identification of mitochondrial dysfunction at coupling site II -- Cellular calcium and mitochondrial dysfunction -- Chronic alcoholism and the mitochondrial F₀F₁-ATP synthase -- Mitochondrial pyrophosphate metabolism in health and disease -- Toxic effects of calcium on mitochondria -- Calcium and the regulation of intramitochondrial dehydrogenases -- Use of fluorescent probes to monitor mitochondrial membrane potential in isolated mitochondria, cell suspensions, and cultured cells -- Genetic and developmental approaches to study of mitochondrial dysfunction -- Commentary: genetic approaches to mitochondrial DNA diseases of oxidative phosphorylation. 
505 0 |a (cont) Developmental aspects of mitochondrial dysfunction -- Mitochondrial DNA synthesis -- Covalent binding of reactive intermediates of xenobiotics to mitochondrial DNA -- Mitochondrial DNA repair and cell injury. 
506 |3 Use copy  |f Restrictions unspecified  |2 star  |5 MiAaHDL 
533 |a Electronic reproduction.  |b [Place of publication not identified] :  |c HathiTrust Digital Library,  |d 2010.  |5 MiAaHDL 
538 |a Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.  |u http://purl.oclc.org/DLF/benchrepro0212  |5 MiAaHDL 
583 1 |a digitized  |c 2010  |h HathiTrust Digital Library  |l committed to preserve  |2 pda  |5 MiAaHDL 
588 0 |a Print version record. 
650 0 |a Mitochondrial pathology. 
650 6 |a Maladies mitochondriales.  |0 (CaQQLa)201-0215121 
650 7 |a Mitochondrial pathology.  |2 fast  |0 (OCoLC)fst01024022 
650 1 7 |a Mitochondri�en.  |2 gtt 
653 0 |a Humans  |a Cells  |a Physiology 
700 1 |a Lash, Lawrence H. 
700 1 |a Jones, Dean P.,  |d 1949- 
776 0 8 |i Print version:  |t Mitochondrial dysfunction.  |d San Diego : Academic Press, �1993  |w (OCoLC)28389597 
830 0 |a Methods in toxicology ;  |v v. 2.  |x 1063-3677 
856 4 0 |u https://sciencedirect.uam.elogim.com/science/book/9780124612051  |z Texto completo