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Enlargement and compaction of particulate solids /
Enlargement and Compaction of Particulate Solids describes the methodology used in the compaction and size enlargement of particulate solids. The discussions are organized into the following topics: characterization of powders and granules before and after compaction; mixing; shear testing; fluidize...
| Clasificación: | Libro Electrónico |
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| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
London ; Boston :
Butterworths,
1983.
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| Colección: | Butterworths monographs in chemical engineering.
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| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Front Cover; Enlargement and Compaction of Particulate Solids; Copyright Page; Preface; Contributors; Table of Contents; CHAPTER 1. Particle characterization by size, shape and surface for individual particles; 1.1 Scope; 1.2 Characterization of individual particles; 1.3 Averages; 1.4 Shape; 1.5 Application of shape factors for surface area evaluation; References; CHAPTER 2. Particle characterization by size, shape and surface for contacted particles; 2.1 Porosity, voidage and particle porosity; 2.2 Nitrogen adsorption; 2.3 Mercury penetration.
- 2.4 Application of nitrogen isotherms Types II and IV and mercury intrusion to compacted solidsReferences; CHAPTER 3. Mixing of powders; 3.1 Powder mixing; 3.2 The mixing process; 3.3 Quantitative assessment of mixture quality; References; CHAPTER 4. Mechanisms of size enlargement; 4.1 Introduction; 4.2 Basic mechanisms; 4.3 The granulation process; Bibliography; References; CHAPTER 5. Flow and handling of solids; the design of solid handling plants; 5.1 Introduction; 5.2 Types of storage hopper; 5.3 Measurement of the failure properties of a particulate solid.
- 5.4 Design of mass flow hoppers5.5 Design of a plant for mass flow; References; CHAPTER 6. Pharmaceutical granulation and compaction; 6.1 Introduction; 6.2 Theoretical considerations; 6.3 Powder preconditioning; 6.4 Compression scale-up; 6.5 Formulation and process optimization; References; CHAPTER 7. Mechanisms of compaction; 7.1 Introduction and scope; 7.2 Application of pressure and frictional effects; 7.3 Particle rearrangement; 7.4 Deformation without rearrangement; 7.5 Strength-producing mechanisms; 7.6 Load removal and stress relaxation; 7.7 Material properties.
- 7.8 Powder compaction equations7.9 Tabletting defects; 7.10 Conclusions; References; CHAPTER 8. Fluidized bed granulation; 8.1 Basic fluidized bed concepts; 8.2 Definitions and applications; 8.3 Variations on the basic process: practical difficulties; 8.4 Quenching; 8.5 Mass and moisture balance; 8.6 Heat balance; 8.7 Particle growth mechanisms: dynamic equilibrium15; 8.8 Growth models and rates; 8.9 Batch versus continuous operation; 8.10 Pilot plant testing; 8.11 The use of inert 'nuclei'; Acknowledgements; References; CHAPTER 9. Compact characterization.
- 9.1 Strength of materials: fundamentals9.2 Soil mechanics stress-strain curves for granular materials; 9.3 Volume reduction in unidimensional consolidation; 9.4 Compaction of powders; References; CHAPTER 10. Instrumentation of tablet machines; 10.1 Introduction; 10.2 Instrumentation of single acting machines; 10.3 Instrumentation of rotary tablet machines; 10.4 Force measuring systems; 10.5 Uses of instrumentation; References; CHAPTER 11. Compaction of ceramics; 11.1 Introduction and scope; 11.2 Pressure transmission through powders; 11.3 Pressure-volume relationships.