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Genetic models of schizophrenia /

This volume focuses on how genetic models for schizophrenia, that is manipulation in genetic susceptibility factors for the disease, have potential in opening a new window of better understanding of etiology-relevant mechanisms. In addition, these models can provide a new platform for drug screening...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Sawa, Akira (Editor )
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam ; Boston : Elsevier, 2009.
Edición:1st ed.
Colección:Progress in brain research ; v. 179.
Temas:
Acceso en línea:Texto completo
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Tabla de Contenidos:
  • Genetic animal models for schizophrenia: advantages and limitations of genetic manipulation in drosophila, zebrafish, rodents, and primates
  • Novel techniques to generate genetic models
  • Animal models for schizophrenia via in utero gene transfer: understanding roles for genetic susceptibility factors in brain development
  • Gene manipulation with of stereotaxic viral infection for psychiatric research: spatiotemporal components for schizophrenia
  • ENU-induced mutant mice for a next-generation gene-targeting system
  • Inducible and conditional transgenic mouse models of schizophrenia
  • Representative models
  • NR1 knockdown mice as a representative model of the glutamate hypothesis of schizophrenia
  • Modeling excess striatal D2 receptors in mice
  • Differential function of phosphodieterase families in the brain: gaining insights through the use of genetically modified animals
  • Gene models of schizophrenia: DISC1 mouse models
  • Sandy (sdy) mouse: a dysbindin-1 mutant relevant to schizophrenia research
  • Other than rodents
  • Zebrafish: a model system to examine the neurodevelopmental basis of schizophrenia
  • Modeling schizophrenia in flies
  • Primate models of schizophrenia: future possibilities.