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Microbial glycobiology : structures, relevance and applications /

This book presents in an easy-to-read format a summary of the important central aspects of microbial glycobiology, i.e. the study of carbohydrates as related to the biology of microorganisms. Microbial glycobiology represents a multidisciplinary and emerging area with implications for a range of bas...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Moran, Anthony P., Holst, Otto, Brennan, Patrick J. Ph. D., Itzstein, Mark von
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam ; Boston : Academic Press/Elsevier, �2009.
Edición:1st ed.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Part I. Microbial glycolipids, glyoproteins and glycopolymers� 1. Overview of the glycosylated components of the bacterial cell wall�� 2. Bacterial cell wall envelope peptidoglycan�� 3. Core oligosaccharide and lipid A components of lipopolysaccharides�� 4. O-Specific polysaccharides of Gram-negative bacteria�� 5. Teichoic acids, lipoteichoic acids, and related cell wall glycopolymers of Gram-positive bacteria�� 6. Bacterial capsular polysaccharides and exopolysaccharides�� 7. Bacterial surface layer glycoproteins and "non-classical" secondary cell wall polymers�� 8. Glycosylation of bacterial and archaeal flagellins�� 9. Glycosylated components of the mycobacterial cell wall: structure and function�� 10. Glycoconjugate structure and function in fungal cell walls�� 11. Cytoplasmic carbohydrate molecules: trehalose and glycogen�� 12. Glycosylated compounds of parasitic protozoa�� 13. Analytical approaches towards the structural characterization of microbial wall glycopolymers�� 14. Single-molecule characterization of microbial polysaccharides�� 15. Viral surface glycoproteins in carbohydrate recognition: structure and modeling�Part II. Synthesis of microbial glycosylated components; A. Biosynthesis and biosynthetic processes� 16. Biosynthesis of bacterial peptidoglycan�� 17. Biosynthesis and membrane assembly of lipid A�� 18. Biosynthesis of O-antigen chains and assembly�� 19. Biosynthesis of cell wall teichoic acid polymers�� 20. Biosynthesis and assembly of capsular polysaccharides�� 21. Biosynthesis of the mycobacterial cell envelope components�� 22. Biosynthesis of fungal and yeast glycans�B. Chemical synthesis�� 23. Chemical synthesis of bacterial lipid A�� 24. Chemical synthesis of the core oligosaccharide of bacterial lipopolysaccharide�� 25. Chemical synthesis of lipoichoic acid and derivatives�� 26. Chemical synthesis of parasitic glycoconjugates and phosphoglycans� Part III. Microbe-host glycosylated interactions�� 27. Bacterial lectin-like interactions in cell recognition and adhesion�� 28. Lectin-like interactions in virus-cell recognition: human immunodeficiency virus and C-type lectin interactions�� 29. Sialic acid-specific microbial lectins��� 30. Bacterial toxins and their carbohydrate receptors at the host-pathogen interface�� 31. Toll-like receptor recognition of lipoglycans, glycolipids and lipopeptides�� 32. NOD receptor recognition of peptidoglycan�� 33. Microbial interaction with mucus and mucins�� 34. Mannose-fucose recognition by DC-SIGN�� 35. Host surfactant proteins in microbial recognition�� 36. T-cell recognition of microbial lipoglycans and glycolipids� Part IV. Biological relevance of microbial glycosylated components; A. Environmental relevance�� 37. Extracellular polymeric substances in microbial biofilms�� 38. Physico-chemical properties of microbial glycopolymers�� 39. Microbial biofilm-related polysaccharides in biofouling and corrosion�� 40. Microbial glycosylated components in plant disease��B. Medical relevance�� 41. Antigenic variation of microbial surface glycosylated molecules�� 42. Phase variation of bacterial surface glycosylated molecules in immune evasion�� 43. Molecular mimicry of host glycosylated structures by bacteria�� 44. Role of microbial glycosylation in host cell invasion� Part V. Biotechnological and medical applications�� 45. Exopolysaccharides produced by lactic acid bacteria in food and probiotic applications�� 46. Industrial exploitation by genetic engineering of bacterial glycosylation systems�� 47. Glycomimetics as inhibitors in anti-infection therapy�� 48. Bacterial polysaccharide vaccines: glycogonjugates and peptide-mimetics�� 49. Immunomodulation by zwitterionic polysaccharides�� 50. Future potential of glycomics in microbiology and infectious diseases�