Cargando…
Variability in human drug response /
Variability in Human Drug Response examines why individual patients differ significantly in their response to drug administration. This book is devoted mainly to pharmacokinetics and covers topics such as drug absorption, distribution, metabolism, and excretion. The sensitivity of tissues of the bod...
| Clasificación: | Libro Electrónico |
|---|---|
| Autores principales: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
London :
Butterworth,
1973.
|
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
| LEADER | 00000cam a2200000 i 4500 | ||
|---|---|---|---|
| 001 | SCIDIR_ocn607851388 | ||
| 003 | OCoLC | ||
| 005 | 20231117033047.0 | ||
| 006 | m o d | ||
| 007 | cr un||||a|a|| | ||
| 008 | 100418s1973 enkah ob 001 0 eng d | ||
| 040 | |a OCLCE |b eng |e pn |c OCLCE |d OCLCQ |d OCLCO |d OCLCQ |d OCLCF |d OPELS |d OCLCO |d N$T |d NLGGC |d YDXCP |d EBLCP |d HEBIS |d OCLCQ |d MERUC |d OCLCQ |d STF |d OCLCQ |d OCLCO |d OCLCA |d UAB |d OCLCQ |d OCLCO |d OCLCQ |d OCL | ||
| 066 | |c (S | ||
| 019 | |a 643585061 |a 896795258 |a 974618161 |a 1257355356 | ||
| 020 | |a 9781483165110 |q (electronic bk.) | ||
| 020 | |a 1483165116 |q (electronic bk.) | ||
| 020 | |z 0407433007 | ||
| 020 | |z 9780407433007 | ||
| 020 | |z 9780407433014 | ||
| 035 | |a (OCoLC)607851388 |z (OCoLC)643585061 |z (OCoLC)896795258 |z (OCoLC)974618161 |z (OCoLC)1257355356 | ||
| 042 | |a dlr | ||
| 050 | 4 | |a RM301 |b .S59 | |
| 050 | 4 | |a RS79 | |
| 060 | 4 | |a QV 38 |b S661v 1973 | |
| 072 | 7 | |a MED |x 071000 |2 bisacsh | |
| 082 | 0 | 4 | |a 615/.7 |
| 100 | 1 | |a Smith, Stephen E. |q (Stephen Edward), |d 1929-2007. | |
| 245 | 1 | 0 | |a Variability in human drug response / |c Stephen E. Smith and Michael D. Rawlins. |
| 260 | |a London : |b Butterworth, |c 1973. | ||
| 300 | |a 1 online resource (viii, 172 pages) : |b illustrations, facsimile | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 504 | |a Includes bibliographical references and index. | ||
| 506 | |3 Use copy |f Restrictions unspecified |2 star |5 MiAaHDL | ||
| 533 | |a Electronic reproduction. |b [Place of publication not identified] : |c HathiTrust Digital Library, |d 2010. |5 MiAaHDL | ||
| 538 | |a Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. |u http://purl.oclc.org/DLF/benchrepro0212 |5 MiAaHDL | ||
| 583 | 1 | |a digitized |c 2010 |h HathiTrust Digital Library |l committed to preserve |2 pda |5 MiAaHDL | |
| 588 | 0 | |a Print version record. | |
| 505 | 0 | |6 880-01 |a Front Cover; Variability in Human Drug Response; Copyright Page; Table of Contents; Preface; CHAPTER 1. Introduction; CHAPTER 2. Pharmacokinetics; Drug absorption; Drug elimination; Drug distribution; Multi-compartmental drug distribution; Multiple-dose kinetics; Kinetics of pharmacological effects; References; CHAPTER 3. Drug Absorption; Reliability or unreliability of drug taking; Drug formulation; pH of the gastric contents; Presence of food and other substances in the lumen; Gastrointestinal motility; Intestinal absorptive function; References; CHAPTER 4. Drug Distribution; Lipid solubility. | |
| 505 | 8 | |a Regional blood flowBinding of drugs; Active transport of drugs; Placental drug transfer; References; CHAPTER 5. Drug Metabolism: General Principles; Pathways of drug metabolism; Hepatic drug metabolism; Drug metabolism in other sites; Influence of age on drug metabolism; Tests of microsomal enzyme function; References; CHAPTER 6. Drug Metabolism: Genetic Factors; Genes of large effect; Genes of small effect; References; CHAPTER 7. Drug Metabolism: Environmental Influences; Enzyme induction; Enzyme inhibition; Liver disease; Renal disease; References; CHAPTER 8. Drug Excretion; Renal excretion. | |
| 520 | |a Variability in Human Drug Response examines why individual patients differ significantly in their response to drug administration. This book is devoted mainly to pharmacokinetics and covers topics such as drug absorption, distribution, metabolism, and excretion. The sensitivity of tissues of the body to drugs and the importance of monitoring drug therapy are also discussed. This book is comprised of 10 chapters and begins with an introduction to variability in clinical response to administration of defined drugs, as well as the importance of closely matching dosage to the individual patient's. | ||
| 650 | 0 | |a Drugs |x Metabolism. | |
| 650 | 0 | |a Drugs |x Dose-response relationship. | |
| 650 | 0 | |a Drug allergy. | |
| 650 | 0 | |a Drugs |x Dosage. | |
| 650 | 0 | |a Drug interactions. | |
| 650 | 2 | |a Dose-Response Relationship, Drug |0 (DNLM)D004305 | |
| 650 | 2 | |a Drug Interactions |0 (DNLM)D004347 | |
| 650 | 2 | |a Pharmaceutical Preparations |x metabolism |0 (DNLM)D004364Q000378 | |
| 650 | 2 | |a Drug Hypersensitivity |0 (DNLM)D004342 | |
| 650 | 2 | |a Pharmaceutical Preparations |x administration & dosage |0 (DNLM)D004364Q000008 | |
| 650 | 2 | |a Drug Combinations |0 (DNLM)D004338 | |
| 650 | 6 | |a M�edicaments |x M�etabolisme. |0 (CaQQLa)201-0046488 | |
| 650 | 6 | |a Posologie. |0 (CaQQLa)201-0023149 | |
| 650 | 6 | |a Allergie aux m�edicaments. |0 (CaQQLa)201-0002240 | |
| 650 | 6 | |a M�edicaments |x Relations dose-effet. |0 (CaQQLa)201-0023148 | |
| 650 | 6 | |a Interactions m�edicamenteuses. |0 (CaQQLa)201-0055133 | |
| 650 | 7 | |a MEDICAL |x Pharmacology. |2 bisacsh | |
| 650 | 7 | |a Drugs |x Dosage. |2 fast |0 (OCoLC)fst01432036 | |
| 650 | 7 | |a Drug interactions. |2 fast |0 (OCoLC)fst00898681 | |
| 650 | 7 | |a Drug allergy. |2 fast |0 (OCoLC)fst00898659 | |
| 650 | 7 | |a Drugs |x Dose-response relationship. |2 fast |0 (OCoLC)fst00898805 | |
| 650 | 7 | |a Drugs |x Metabolism. |2 fast |0 (OCoLC)fst00898845 | |
| 700 | 1 | |a Rawlins, Michael D. |q (Michael David), |e author. | |
| 776 | 0 | 8 | |i Print version: |a Smith, Stephen E. (Stephen Edward), 1929-2007. |t Variability in human drug response. |d London : Butterworth, 1973 |w (DLC) 74195616 |w (OCoLC)947261 |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780407433014 |z Texto completo |
| 880 | 8 | |6 505-01/(S |a Drugs in renal failureBiliary excretion; Other routes of excretion; References; CHAPTER 9. Tissue Sensitivity; Quantitative differences in drug response; Abnormal drug responses; References; CHAPTER 10. Monitoring Drug Therapy; Monitoring of drug effects; Monitoring of plasma levels -- a pharmacokinetic approach; References; APPENDIX A:Calculation of Drug Dosage in Renal Failure on the Basis of Creatinine Clearance; APPENDIX Β:Antibiotic Dosage in Renal Failure; Index. | |