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The prostaglandins : pharmacological and therapeutic advances /

The Prostaglandins: Pharmacological and Therapeutic Advances provides a concise account of the more important theoretical developments and areas in which the prostaglandins are being introduced into clinical practice or have potential clinical application. Chapters I to IV of this book deal with the...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Cuthbert, Maurice Frederick
Formato: Electrónico eBook
Idioma:Inglés
Publicado: London : Heinemann Medical, 1973.
Temas:
Acceso en línea:Texto completo

MARC

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100 1 |a Cuthbert, Maurice Frederick. 
245 1 4 |a The prostaglandins :  |b pharmacological and therapeutic advances /  |c edited by M.F. Cuthbert. 
260 |a London :  |b Heinemann Medical,  |c 1973. 
300 |a 1 online resource (xi, 332 pages) :  |b illustrations 
336 |a text  |b txt  |2 rdacontent 
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504 |a Includes bibliographical references and index. 
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505 0 |a Front Cover; The Prostaglandins: Pharmacological and Therapeutic Advances; Copyright Page; Contributors; Table of Contents; Preface; Acknowledgements; CHAPTER I. Chemistry Structure and Availability; 1. NOMENCLATURE; 2. SOURCES OF SUPPLY; 3. CHEMICAL PROPERTIES; 4. STRUCTURE-ACTIVITY RELATIONSHIPS; REFERENCES; CHAPTER II. General Pharmacology of Prostaglandins; 1. STRUCTURE-ACTIVITY RELATIONSHIPS; 2. CELLULAR AND SUBCELLULAR MECHANISMS OF THE ACTIONS OF PROSTAGLANDINS; 3. SYSTEMIC ACTIONS OF PROSTAGLANDINS; 4. PROSTAGLANDIN INHIBITORS; 5. SUMMARY AND CONCLUSION; ACKNOWLEDGMENTS; REFERENCES. 
505 8 |a CHAPTER III. Distribution and MetabolismDistribution; Metabolism; Conclusions; REFERENCES; CHAPTER IV. Cyclic AMP and the Mechanism of Action of the Prostaglandins; 1. INTRACELLULAR CONCENTRATIONS OF CYCLIC AMP; 2. THE SECOND MESSENGER HYPOTHESIS; 3. PROSTAGLANDINS AND THE SECOND MESSENGER SYSTEM; 4. PROSTAGLANDINS AND CYCLIC AMP IN DISEASE; REFERENCES; CHAPTER V. Pharmacology and Therapeutic Applications of Prostaglandins in the Human Reproductive System; 1. NON-PREGNANT UTERUS; 2. EARLY PREGNANT UTERUS; 3. PREGNANT UTERUS AT TERM; 4. INTRAUTERINE DEATH OF THE FOETUS; REFERENCES. 
505 8 |a CHAPTER VI. Vasoactive and Anti-hypertensive Effects of Prostaglandins and other Renomedullary Lipids1. ANTIHYPERTENSIVE FUNCTION OF THE WHOLE KIDNEY; 2. ANTIHYPERTENSIVE FUNCTION OF THE RENAL MEDULLA; 3. VASODEPRESSOR LIPID (VDL) OF THE RENAL MEDULLA; 4. THE RENOMEDULLARY PROSTAGLANDINS; 5. CELLULAR SOURCE OF RENOMEDULLARY PROSTAGLANDINS; 6. CARDIOVASCULAR EFFECTS OF RENOMEDULLARY PROSTAGLANDINS; 7. EFFECT ON RENAL VASCULATURE ANDRENAL FUNCTION; 8. RELEASE OF PROSTAGLANDINS INTO THE RENAL VENOUS EFFLUENT; 9. RENOMEDULLARY PROSTAGLANDINS IN HYPERTENSION. 
505 8 |a 10. SPECULATIONS ON THE ACTION OF RENOMEDULLARY PROSTAGLANDINS IN HYPERTENSION11. ANTIHYPERTENSIVE NEUTRAL RENOMEDULLARY LIPID (ANRL); 12. CONCLUSIONS AND THERAPEUTIC IMPLICATIONS; REFERENCES; CHAPTER VII. Prostaglandins and Respiratory Smooth Muscle; 1. EFFECTS ON ISOLATED RESPIRATORY SMOOTH MUSCLE; 2. EFFECTS ON BRONCHIAL RESISTANCE; 3. POTENCY IN RELATION TO ROUTE OF ADMINISTRATION; 4. MECHANISM OF ACTION; 5. PHYSIOLOGICAL AND PATHOLOGICAL INVOLVEMENT; 6. THERAPEUTIC POSSIBILITIES; REFERENCES; CHAPTER VIII. Prostaglandins and the Gastro-intestinal Tract. 
505 8 |a 1. EFFECTS OF PROSTAGLANDINS ON GASTRO-INTESTINAL MOTILITY IN VITRO2. EFFECTS ON GASTRO-INTESTINAL MOTILITY IN VIVO; 3. EFFECTS OF PROSTAGLANDINS ON INTESTINAL WATER AND ELECTROLYTE TRANSPORT; 4. EFFECTS OF PROSTAGLANDINS ON GASTRIC SECRETION; 5. EFFECTS OF PGs ON GASTRIC SECRETION IN HUMANS; 6. EFFECTS ON PANCREATIC SECRETION; 7. PHYSIOLOGICAL ROLE OF PROSTAGLANDINS IN THE GASTRO-INTESTINAL TRACT; 8. PATHOLOGICAL ROLES OF PROSTAGLANDINS; REFERENCES; Index. 
520 |a The Prostaglandins: Pharmacological and Therapeutic Advances provides a concise account of the more important theoretical developments and areas in which the prostaglandins are being introduced into clinical practice or have potential clinical application. Chapters I to IV of this book deal with the chemistry and classification, distribution and metabolism, general pharmacology, and mechanism of action. The rest of the chapters discuss the relationship of the prostaglandins to the reproductive, cardiovascular, respiratory, and gastro-intestinal systems with an emphasis on the human pharmacolog. 
546 |a English. 
650 0 |a Prostaglandins. 
650 2 |a Prostaglandins  |x pharmacology  |0 (DNLM)D011453Q000494 
650 2 |a Prostaglandins  |x therapeutic use  |0 (DNLM)D011453Q000627 
650 2 |a Prostaglandins  |0 (DNLM)D011453 
650 6 |a Prostaglandines.  |0 (CaQQLa)201-0031328 
650 7 |a MEDICAL  |x Pharmacology.  |2 bisacsh 
650 7 |a Prostaglandins  |2 fast  |0 (OCoLC)fst01079463 
653 |a Medicine  |a Drugs: Prostaglandins Reviews of research 
776 0 8 |i Print version:  |a Cuthbert, Maurice Frederick.  |t Prostaglandins: pharmacological and therapeutic advances.  |d London, Heinemann Medical, 1973  |w (DLC) 73595432  |w (OCoLC)715299 
856 4 0 |u https://sciencedirect.uam.elogim.com/science/book/9780433070009  |z Texto completo