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A history of immunology /

This is a professional-level intellectual history of the development of immunology from about 1720 to about 1970. Beginning with the work and insights of the early immunologists in the 18th century, Silverstein traces the development of the major ideas which have formed immunology down to the matura...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Silverstein, Arthur M.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: San Diego : Academic Press, �1989.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Front Cover; A History of Immunology; Copyright Page; Table of Contents; List of Plates; Preface; On History and Historians; Chapter 1. Theories of Acquired Immunity; Magic and Theurgic Origin of Disease; Expulsion Theories of Acquired Immunity; A Distention Theory: Iatrophysics; Depletion Theories; The Retention Theory and Other Concepts; Chapter 2. The Royal Experiment on Immunity, 1721-1722; The Introduction of Inoculation to England; The Royal Experiment; Discussion; Chapter 3. Cellular versus Humoral Immunity: Determinants and Consequences of an Epic Nineteenth-Century Battle
  • Background to the ConflictCellular versus Humoral Immunity; Consequences of the Humoralist Victory; Chapter 4. Theories of Antibody Formation; Antigen Incorporation Theories; Ehrlich's Side-Chain Theory; Instruction Theories; Selection Theories; Conclusions; Chapter 5. The Concept of Immunological Specificity; The Background to Biological Specificity; Paul Ehrlich: The First Immunochemist; The Ehrlich-Bordet Debate; The Ehrlich-Gruber Debate; Karl Landsteiner, The Compleat Immunologist; Specificity and Theories of Antibody Formation; Chapter 6. Immunological Specificity, Continued
  • The Structural Basis for Immunological SpecificitySpecificity in Cellular Immunity; Specific Triggers and Nonspecific Amplifiers; Waiting for the End?; The Repertoire Paradox; The Evolutionary Paradox; Conclusions; Chapter 7. Horror Autotoxicus: The Concept of Autoimmunity; The Real Meaning of Horror Autotoxicus; The Classical Period of Autoimmunity Research; The Dark Ages of Autoimmunity Research; The Modern Period of Autoimmunity Research; Phenomenological and Technical Progress; Conclusions
  • Chapter 8. The Donath-Landsteiner Autoantibody: The Incommensurable Languages of Immunological DisputeThe Donath-Landsteiner Discovery, 1904; Linguistic Aspects of the Great Immunological Debate; Karl Landsteiner's Scientific Style; Contemporary Views of the Donath- Landsteiner Report; The Lexicons of Scientific Dispute; Chapter 9. Allergy and Immunopathology: The Price of Immunity; Early Observations; The Debate on Mechanisms of Allergy; Progress in Allergy: The Clinical Discipline46; The Concept of Allergy of Infection
  • Progress on Delayed (Tuberculin)-Type Hypersensitivity
  • Other Immunopathological ProcessesImmunological Deficiency Diseases; Conclusions; Chapter 10. Anti-antibodies and Anti-idiotype Immunoregulation, 1899-1904; Idiotypes and Anti-idiotypes, 1963-1985; The Background to Anti-antibodies, 1890-1899; Anti-antibodies, 1899-1904; The Demise of Anti-antibody Theories, 1901-1905; Conclusions; Chapter 11. Transplantation and Immunogenetics; Transplantation Biology; The Renaissance of Transplantation Biology; Progress in Transplantation Research; Immunogenetics; Chapter 12. Magic Bullets and Poisoned Arrows: The Uses of Antibody; Immunotherapy