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The quinolones /
The Quinolones covers reviews on the history, chemistry and mechanism of action, in vitro properties, pharmacokinetics, clinical overview, toxicity, adverse effects and drug interactions, and future prospects of the 4-quinolones. The book discusses the microbiology of quinolones, particularly with c...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
London ; San Diego :
Academic Press,
1988.
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| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 245 | 0 | 4 | |a The quinolones / |c edited by Vincent T. Andriole. |
| 260 | |a London ; |a San Diego : |b Academic Press, |c 1988. | ||
| 300 | |a 1 online resource (xii, 262 pages) : |b illustrations | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 504 | |a Includes bibliographical references and index. | ||
| 506 | |3 Use copy |f Restrictions unspecified |2 star |5 MiAaHDL | ||
| 533 | |a Electronic reproduction. |b [Place of publication not identified] : |c HathiTrust Digital Library, |d 2010. |5 MiAaHDL | ||
| 538 | |a Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. |u http://purl.oclc.org/DLF/benchrepro0212 |5 MiAaHDL | ||
| 583 | 1 | |a digitized |c 2010 |h HathiTrust Digital Library |l committed to preserve |2 pda |5 MiAaHDL | |
| 588 | 0 | |a Print version record. | |
| 505 | 0 | |a Front Cover; The Quinolones; Copyright Page; Contributers; Preface; Table of Contents; Chapter 1. The Quinolones: History and Overview; 1.1 Mechanism of action; 1.2 Activity in vitro; 1.3 Bacterial resistance; 1.4 Clinical pharmacology; 1.5 Clinical uses; 1.6 Adverse effects; 1.7 Summary; References; Chapter 2. Chemistry and Mechanisms of Action of the Quinolone Antibacterials; 2.1 Chemistry; 2.2 Target site; 2.3 Selectivity; 2.4 Antibacterial activities; 2.5 4-Quinolone interactions with ions; 2.6 4-Quinolone interactions with oxygen; 2.7 4-Quinolone interactions with other antibacterials. | |
| 505 | 8 | |a 2.8 ResistanceReferences; Chapter 3. In vitro Properties of the Quinolones; 3.1 Gram-negative aerobes; 3.2 Gram-positive aerobes; 3.3 Anaerobes; 3.4 Miscellaneous organisms; 3.5 Development of resistance; 3.6 Conclusion; References; Chapter 4. Pharmacokinetics of Fluorinated Quinolones; Introduction; 4.1 Serum concentrations; 4.2 Urine concentrations; 4.3 Steady state; 4.4 Pharmacokinetics; 4.5 Elimination; 4.6 Bioavailability; 4.7 Impaired renal function; 4.8 Impaired liver function; 4.9 Impact of food; 4.10 Interactions; 4.11 Influence of disease; 4.12 Extravascular penetration; References. | |
| 505 | 8 | |a Chapter 5. Clinical Overview of the Newer 4-Quinolone Antibacterial AgentsIntroduction; 5.1 Urinary tract infections; 5.2 Respiratory tract infections; 5.3 Gastrointestinal infections; 5.4 Skin and soft-tissue infections; 5.5 Osteomyelitis; 5.6 Sexually transmitted diseases; 5.7 Immunocomprised patients; 5.8 Central nervous system infections; 5.9 Other potential uses; 5.10 Summary; References; Chapter 6. Safety Overview: Toxicity, Adverse Effects and Drug Interactions; 6.1 Introduction; 6.2 Toxicity of quinolones; 6.3 Adverse effects of fluoroquinolones in clinical studies. | |
| 505 | 8 | |a 6.4 Drug interactionsReferences; Chapter 7. The Quinolones: Prospects; 7.1 Microbiology; 7.2 Resistance of bacteria to quinolones; 7.3 Pharmacology; 7.4 Toxicological issues; 7.5 Clinical considerations for future use of quinolones; 7.6 Prophylactic use of quinolones; 7.7 Summary; References; Index. | |
| 520 | |a The Quinolones covers reviews on the history, chemistry and mechanism of action, in vitro properties, pharmacokinetics, clinical overview, toxicity, adverse effects and drug interactions, and future prospects of the 4-quinolones. The book discusses the microbiology of quinolones, particularly with consideration of the development of resistance, pharmacology, toxicology, and clinical uses. Chemists, microbiologists, pharmacologists and clinicians will find the book useful. | ||
| 546 | |a English. | ||
| 650 | 0 | |a Quinolone antibacterial agents. | |
| 650 | 2 | |a Quinolones |0 (DNLM)D015363 | |
| 650 | 6 | |a Quinolones. |0 (CaQQLa)201-0193214 | |
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| 650 | 7 | |a Quinolone antibacterial agents |2 fast |0 (OCoLC)fst01085873 | |
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| 650 | 7 | |a Quinol�eines. |2 fmesh | |
| 650 | 7 | |a Gyrasehemmer |2 gnd |0 (DE-588)4217839-3 | |
| 653 | |a Medicine |a Drug therapy |a Quinolones | ||
| 700 | 1 | |a Andriole, Vincent T. | |
| 776 | 0 | 8 | |i Print version: |t Quinolones. |d London ; San Diego : Academic Press, 1988 |w (DLC) 89175399 |w (OCoLC)19982881 |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780120595150 |z Texto completo |