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Inhibition of polyamine metabolism : biological significance and basis for new therapies /
Inhibition of polyamine metabolism.
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Orlando :
Academic Press,
1987.
|
| Temas: | |
| Acceso en línea: | Texto completo |
MARC
| LEADER | 00000cam a2200000 a 4500 | ||
|---|---|---|---|
| 001 | SCIDIR_ocn568141715 | ||
| 003 | OCoLC | ||
| 005 | 20231117032951.0 | ||
| 006 | m o d | ||
| 007 | cr cnu---unuuu | ||
| 008 | 100324s1987 flua ob 001 0 eng d | ||
| 040 | |a OCLCE |b eng |e pn |c OCLCE |d OCLCQ |d OPELS |d E7B |d N$T |d OCLCO |d IDEBK |d OCLCQ |d UIU |d YDXCP |d EBLCP |d DEBSZ |d OCLCQ |d UAB |d OCLCQ |d MERUC |d OCLCQ |d OCLCO |d OCLCA |d OCLCQ |d LEAUB |d OCLCO |d OCLCQ |d OCLCA |d OCLCO |d OCLCQ | ||
| 019 | |a 603989563 |a 850150470 | ||
| 020 | |a 9780323152327 |q (electronic bk.) | ||
| 020 | |a 0323152325 |q (electronic bk.) | ||
| 020 | |z 9780124818354 | ||
| 020 | |z 0124818358 | ||
| 035 | |a (OCoLC)568141715 |z (OCoLC)603989563 |z (OCoLC)850150470 | ||
| 042 | |a dlr | ||
| 050 | 4 | |a QP801.P638 |b I55 1987 | |
| 060 | 4 | |a QU 60 |b I55 1987 | |
| 072 | 7 | |a MED |x 067000 |2 bisacsh | |
| 082 | 0 | 4 | |a 574.2/192 |2 22 |
| 245 | 0 | 0 | |a Inhibition of polyamine metabolism : |b biological significance and basis for new therapies / |c edited by Peter P. McCann, Anthony E. Pegg, Albert Sjoerdsma. |
| 260 | |a Orlando : |b Academic Press, |c 1987. | ||
| 300 | |a 1 online resource (xvi, 371 pages) : |b illustrations | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 504 | |a Includes bibliographical references and index. | ||
| 538 | |a Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. |u http://purl.oclc.org/DLF/benchrepro0212 |5 MiAaHDL | ||
| 583 | 1 | |a digitized |c 2010 |h HathiTrust Digital Library |l committed to preserve |2 pda |5 MiAaHDL | |
| 588 | 0 | |a Print version record. | |
| 505 | 0 | |a Front Cover; Inhibition of Polyamine Metabolism: Biological Significance and Basis for New Therapies; Copyright Page; Table of Contents; Preface; Introduction: Polyamine Metabolism; Chapter 1. Inhibition of Basic Amino Acid Decarboxylases Involved in Polyamine Biosynthesis; I. Introduction; II. Properties of ODC; III. Mechanism of Action of ODC; IV. Inhibition of ODC; V. Inhibition of Arginine Decarboxylase and Lysine Decarboxylase; VI. Conclusion; References; Chapter 2. Pharmacologic Interference with Enzymes of Polyamine Biosynthesis and of 5'-Methylthioadenosine Metabolism; I. Introduction. | |
| 505 | 8 | |a II. S-Adenosylmethionine Decarboxylase (AdoMetDC)III. Spermidine Synthase; IV. Spermine Synthase; V. Enzymatic Degradation of 5'-Methylthioadenosine (MTA); References; Chapter 3. Inhibition of Enzymes Oxidizing Polyamines; I. Introduction; II. Copper Amine Oxidases; III. Flavin-Dependent Enzymes in Polyamine Catabolism; IV. Biological Consequences of Polyamine Oxidase Inactivation; V. Conclusions; References; Chapter 4. Molecular and Cellular Functions of the Polyamines; I. Introduction; II. Nucleic Acid Structure; III. Macromolecular Synthesis; IV. Topoisomerase Activity. | |
| 505 | 8 | |a v. Membrane Structure and FunctionAcknowledgments; References; Chapter 5. The Use of Inhibitors to Study the Biochemistry and Molecular Biology of Polyamine Biosynthesis and Uptake; I. Introduction; II. Studies of Ornithine Decarboxylase; III. Studies of S-Adenosylmethionine Decarboxylase (AdoMetDC); IV. Studies of Polyamine Transport; References; Chapter 6. Inhibitors of Polyamine Biosynthesis: Cellular and in Vivo Effects on Tumor Proliferation; I. Introduction; II. Polyamine Biosynthesis in Normal and Transformed Cells; III. Inhibitors of Polyamine Biosynthesis. | |
| 505 | 8 | |a IV. Cellular Effects of Polyamine InhibitorsV. Polyamine Inhibitors: In Vivo Effects against Experimental Tumors; VI. Summary; References; Chapter 7. Polyamine Inhibition in Vivo and in Organ Growth and Repair; I. Introduction; II. In Vivo Biochemistry of Polyamine Biosynthesis Inhibitors; III. Consequences of Polyamine Inhibition on Organ Growth and Repair; IV. Conclusions; References; Chapter 8. Polyamine Synthesis Inhibitors Act as both Inducers and Suppressors of Cell Differentiation; I. Introduction; II. Germ Cells and Embryos; III. Organ Systems. | |
| 505 | 8 | |a IV. Primary Cell Cultures and Established Cell LinesV. Summary and Future Prospects; Acknowledgments; References; Chapter 9. The Contragestational Effects of Ornithine Decarboxylase Inhibition; I. Introduction; II. Polyamine Biochemical Changes during Gestation in Mammals; III. Effects of Inhibitors of ODC on Gestation; IV. Clinical Significance of the Contragestational Effects of ODC Inhibition; V. Conclusion; References; Chapter 10. Modulation of Antineoplastic Drug Action by Inhibitors of Polyamine Biosynthesis; I. Introduction; II. Goals of Combination Chemotherapy. | |
| 520 | |a Inhibition of polyamine metabolism. | ||
| 650 | 0 | |a Polyamines |x Synthesis |x Inhibitors |x Physiological effect. | |
| 650 | 0 | |a Polyamines |x Synthesis |x Inhibitors |x Therapeutic use. | |
| 650 | 0 | |a Polyamines |x Metabolism |x Regulation. | |
| 650 | 2 | |a Polyamines |x metabolism |0 (DNLM)D011073Q000378 | |
| 650 | 6 | |a Polyamines |0 (CaQQLa)201-0058116 |x Synth�ese |0 (CaQQLa)201-0374877 |x Inhibiteurs |0 (CaQQLa)201-0374877 |x Effets physiologiques. |0 (CaQQLa)201-0374337 | |
| 650 | 6 | |a Polyamines |0 (CaQQLa)201-0058116 |x Synth�ese |0 (CaQQLa)201-0374877 |x Inhibiteurs |0 (CaQQLa)201-0374877 |x Emploi en th�erapeutique. |0 (CaQQLa)201-0373975 | |
| 650 | 6 | |a Polyamines |0 (CaQQLa)201-0058116 |x M�etabolisme |0 (CaQQLa)201-0379671 |x R�egulation. |0 (CaQQLa)201-0379671 | |
| 650 | 7 | |a MEDICAL |x Pathology. |2 bisacsh | |
| 653 | |a Organisms |a Polyamines |a Biosynthesis |a Inhibitors | ||
| 700 | 1 | |a McCann, Peter P. | |
| 700 | 1 | |a Pegg, Anthony E. | |
| 700 | 1 | |a Sjoerdsma, Albert, |d 1924- | |
| 776 | 0 | 8 | |i Print version: |t Inhibition of polyamine metabolism. |d Orlando : Academic Press, 1987 |z 9780124818354 |w (DLC) 86032147 |w (OCoLC)15016944 |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780124818354 |z Texto completo |