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Proteolysis and physiological regulation : proceedings of the Miami winter symposia, January 1976 /

Proteolysis and Physiological Regulation.

Detalles Bibliográficos
Clasificación:Libro Electrónico
Autores Corporativos: University of Miami. Department of Biochemistry, Papanicolaou Cancer Research Institute
Otros Autores: Ribbons, Douglas W., Brew, Keith
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York : Academic Press, 1976.
Colección:Miami winter symposia ; v. 11.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Front Cover; Proteolysis and Physiological Regulation: Miami Winter Symposia; Copyright Page; Table of Contents; SPEAKERS, CHAIRMEN, AND DISCUSSANTS; PREFACE; Part I: Proteolysis and Physiological Regulation; CHAPTER 1. MY LIFE WITH PROTEINS AND PROSTHETIC GROUPS; Liver alcohol dehydrogenase and alcohol combustion; Ternary complexes; Three-dimensional structure of the ADH-molecule; Inhibitors; Alcohol and fat metabolism; In Conclusion; REFERENCES; CHAPTER 2. THE ROLE OF PROTEASES IN BIOLOGICAL REGULATION; Abstract:; CONCLUSIONS; REFERENCES; DISCUSSION.
  • CHAPTER 3. STRUCTURAL STUDIES ON THE PANCREATIC TRYPSIN INHIBITOR
  • TRYPSIN COMPLEX AND ITS FREE COMPONENTS: STRUCTURE AND FUNCTION RELATIONSHIP IN SERINE PROTEASE INHIBITION AND CATALYSIS1. Introduction; 2. Results and Discussions; Acknowledgement; References; DISCUSSION; CHAPTER 4. THE PROTEOLYTIC ENZYMES OF THE K-1 STRAIN OF STREPTOMYCES GRI SEUS OBTAINED FROM A COMMERCIAL PREPARATION (PRONASE). X I . EVOLUTIONARY IMPLICATIONS; INTRODUCTION; TRYPSIN; CHYMOELASTASES; SUBTILISIN
  • LIKE PROTEASE; CARBOXYPEPTIDASE; AMINOPEPTIDASES; CONCLUDING REMARKS; DISCUSSION.
  • CHAPTER 5. RELATIONSHIPS BETWEEN THE STRUCTURES AND ACTIVITIES OF SOME MICROBIAL SERINE PROTEASES. I. PURIFICATION, ENZYMIC PROPERTIES AND PRIMARY STRUCUTRES OF STREPTOMYCES GRISEUS PROTEASES A, B AND TRYPSIN. INTRODUCTION; MYXOBACTER a-LYTIC PROTEASE; ISOLATION OF STREPTOMYCES GRISEUSPROTEASES A, B AND TRYPSIN FROM 'PRONASE'; PROTEASES A AND B; STREPTOMYCES GRISEUS TRYPSIN (SGT); DISCUSSION; REFERENCES; CHAPTER 6. RELATIONSHIP BETWEEN THE STRUCTURES AND ACTIVITIES OF SOME MICROBIAL SERINE PROTEASES. II. COMPARISON OF THE TERTIARY STRUCTURES OF MICROBIAL AND PANCREATIC SERINE PROTEASES.
  • Introduction comparison of microbial and pancreatic serine protease structure; substrate specificity site; references; discussion; chapter 7. biological functions of activated complement proteins in normal and disease states; introduction; background; role of immunoglobulins; chemotaxis; receptor sites for c on cell membranes: role in recognition and biologic activity; consequences of cactivation and in activationin various diseases; inactivation of c proteins by microbial factors; desirable effects of c component in activation by chemotherapy.
  • Undesirable effects of c component inactivation by chemotherapyreferences; discussion; chapter 8. the nature and reactions of complement enzymes; introduction and overview; enzymes of teclassic alcomplement pathway; enzymes of the alternative complement pathway; regulators of the complement system; conclusions; references; discussion; chapter 9. erine proteases of coagulation and their inhibitors; references; discussion; chapter 10. homologous ""kringle"" structures common to plasminogen and prothrombin. substrate specificity of enzymes activating prothrombin and plasminogen; introduction.