Kinetics of experimental tumour processes /

Kinetics of Experimental Tumour Processes focuses on the principles of the kinetics of experimental malignant growth. This book also looks into the molecular mechanisms of chemotherapy and certain problems of carcinogenesis and biochemistry. Organized into eight chapters, this monograph first descri...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: �Emanu�el�, N. M. (Nikola�i Markovich), 1915-1984
Formato: Electrónico eBook
Idioma:Inglés
Ruso
Publicado: Oxford ; New York : Pergamon Press, �1982.
Edición:1st English ed.
Temas:
Oncology, Experimental.
Cancer cells > Growth.
Antineoplastic agents.
Dynamics.
Antimitotic agents.
Antineoplastic Agents > pharmacology
Kinetics
Neoplasms > drug therapy
Neoplasms, Experimental
Antineoplastic Agents
Antimitotic Agents
Canc�erologie exp�erimentale.
Cellules canc�ereuses > Croissance.
Anticanc�ereux.
Dynamique.
kinetics (dynamics)
HEALTH & FITNESS > Diseases > General.
MEDICAL > Clinical Medicine.
MEDICAL > Diseases.
MEDICAL > Evidence-Based Medicine.
MEDICAL > Internal Medicine.
Antimitotic agents
Antineoplastic agents
Cancer cells > Growth
Dynamics
Oncology, Experimental
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Front Cover; Kinetics of Experimental Tumour Processes; Copyright Page; Table of Contents; Foreword to the English edition; Foreword; CHAPTER 1. THE KINETICS OF TUMOUR GROWTH; 1. KINETIC CURVES; 2. EXPERIMENTAL POINT AND THE EXPERIMENTAL KINETIC CURVE; 3. FUNCTIONS USED IN THE DESCRIPTION OF TUMOUR GROWTH; 4. ESTIMATION OF KINETIC PARAMETERS; 5. QUANTITATIVE EFFICIENCY CRITERIA FOR TUMOUR GROWTH TREATMENT; CHAPTER 2. KINETICS OF EXPERIMENTAL TUMOUR GROWTH; 1. SOLID TUMOURS AND THEIR ASCITES FORMS; 3. SPONTANEOUS TUMOURS AND THEIR FIRST GENERATIONS.
  • 4. critical phenomena in the development of experimental tumours5. comparative kinetic analysis of the growth of primary tumours and their metastases; 6. generalization of data on the kinetics of tumour growth; chapter 3. kinetic parameters of variousantitumour effects; 1. alkylating compounds; 2. n-nitrosocarbamides; 3. antimetabolites; 4. antibiotics; 5. phenolic compounds; 6. drugs displaying various mechanisms of action; 7. comparison of the effefectiveness of various antitumour drugs; 8. combined chemotherapy; 9. combined effect of drugs and irradiation.
  • 10. response of primary tumours and metastases to chemotherapy11. surgery of experimental tumours; chapter 4. pharmacokinetics of antitumour agents; 1. methods and models; 2. pharmacokinetics in cancer chemotherapy; chapter 5. molecular mechanisms in chemotherapy; 1. free radical mechanisms of the action of phenol compounds; 2. interaction of alkylnitrosoureas with nucleic acids; 3. effect of diazoketones on biosynthesis processes; chapter 6. free radicals and tumour growth; 1. nature of parmagnetic centres in normal and tumour tissues.
  • 2. changes in paramagnetic properties of tissues during carcinogenesis3. kinetic regularities for changes in the radical content in the course of tumour growth; 4. effect of antitumour agents on free radical content; 5. certain regularities of change in the free radical content of human tumours; chapter 7. kinetic biochemistry of tumours; 1. carbohydrate metabolism; 2. nucleic acids; 3. lipids; chapter 8. disturbance of structure and biosynthesis of informational macromolecules in malignant growth; 1. structural changes in biomacromolecules; 2. biosynthesis of nucleic acids and proteins.
  • 3. nucleic acids and mitochondrial proteinsbibliography; index.

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