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Biology of myeloma /

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Potter, Michael, 1924-2013
Formato: Electrónico eBook
Idioma:Inglés
Publicado: New York : Elsevier/North-Holland, �1980.
Edición:1980 ed.
Colección:Progress in myeloma.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Cover image; Title page; Table of Contents; Inside Front Cover; Copyright; Preface; Contributors; Chapter 1: Epidemiology of Multiple Myeloma and Related Plasma Cell Disorders: An Analytic Review; Publisher Summary; Introduction; Multiple Myeloma; Waldenstr�om's Macroglobulinemia; Benign Monoclonal Gammopathy (BMG); Heavy Chain Disease; Chronic Antigenic Stimulation; Conclusions; ACKNOWLEDGMENTS; Chapter 2: In Vitro Bone Resorption by Human Myeloma Cells; Publisher Summary; Introduction; Methods; Clinical Characteristics of the Patients Studied; Results; Discussion; Summary and Conclusions
  • ACKNOWLEDGMENTChapter 3: Plasma Cell Myeloma and Waldenstr�om's Macroglobulinemia in Black and White South Africans; Summary; Introduction; Patients and Methods; Results; Discussion; Chapter 4: In Vivo Pulse Labeling Studies of Murine LPC-1 Plasmacytoma Using 6-14C-Arginine; Introduction; Materials and Methods; Results; Detection of "Eclipse" Phenomenon; Modification of the "Eclipse" Period; Discussion; ACKNOWLEDGMENTS; Chapter 5: Myelomas as Models to Study Activation and Suppression of Normal Lymphocytes; Publisher Summary; I Introduction
  • II Cellular Events Associated with Immune Induction and ToleranceIII Membrane Events Associated with B Cell Activation and Tolerance; IV Membrane Events Associated with the Binding of Immunogenic or Tolerogenic Ligands to Myelomas; V Inhibition of Myeloma Antibody Production by Antigens; VI Regulation of Myeloma Growth and Function by Anti-Idiotypic Antibodies; VII Regulation of Myeloma Growth and Function by T Lymphocytes; VIII Somatic Cell Hybrids (Hybridomas) A Source of Homogeneous Antigen Reactive B Cells; IX Summary and Conclusions
  • Chapter 6: Regulation of Murine Myeloma Cell Growth and Differentiation: Cellular and Molecular Mechanisms, and Therapeutic ImplicationsPublisher Summary; Introduction; Myeloma Proteins as Tumor-Specific Transplantation Antigens; MOPC-315 Cells Differentiate during In Vivo Growth; MOPC-315 Cells are Antigen-Sensitive; T Cells and Macrophages Mediate Antigen-Specific Regulation of MOPC-315; Antigen-Specific Regulation of Subcutaneous and Disseminated MOPC-315; Role of T Cells in (Id315) Idiotype-Specific Regulation of MOPC-315
  • Neoplastic B Cells as Targets of the Host's Immunoregulatory ApparatusSummary; ACKNOWLEDGMENT; Chapter 7: Characteristics of Multiple Myeloma as an Immunodeficiency Disease; Publisher Summary; Immune Impairment at the Clinical Level; Immunological Defects; Chalone theory; "Immunologic Conversion"; Depression of Polyclonal B-cell Numbers; Chapter 8: Immunodeficiency Induced by Plasma Cell Tumors: Comparison of Findings in Human and Murine Hosts; Summary; Introduction; Measurement of CMI Responses In Vivo; Measurement of Anti-PC Immunity; Measurement of Non-specific Cell-mediated Cytotoxicity