Cargando…
Basic pharmacology /
Basic Pharmacology, Third Edition aims to present accounts of drug actions and their mechanisms in a compact, inexpensive, and updated form, and explain the basis of the therapeutic exploitation of drugs. This book is divided into sections that follow a particular theme and is introduced by the rele...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Oxford ; Boston :
Butterworth-Heinemann,
1991.
|
| Edición: | 3rd ed. |
| Temas: | |
| Acceso en línea: | Texto completo |
Tabla de Contenidos:
- Front Cover; Basic Pharmacology; Copyright Page; Table of Contents; Preface; Introduction; List of abbreviations; Chapter 1. General pharmacology; Mechanisms of drug action; Receptor mediation of drug effects; Adverse effects of drugs; Allergically determined hypersensitivity to drugs; Genetically determined idiosyncracy to drugs (pharmacogenetics); Developmental toxicity; Adverse drug interactions; Abuse of drugs; Drug design, development and testing.
- Chapter 2. Drug action on peripheral excitable tissues
- drugs acting on signalling and transduction mechanisms directly related to receptors for the neurotransmitters acetylcholine and noradrenalineAnatomy and physiology of the (efferent) peripheral nervous system and its effectors; The effector cells innervated by postganglionic autonomic neurones: important effects caused by nervous activity; The pharmacology of cholinergic axons and their terminals; The pharmacology of the cholinoceptors of skeletal muscle; The pharmacology of the cholinoceptors of ganglia.
- The pharmacology of the cholinoceptors of smooth muscle, cardiac muscle and exocrine glandsCholinesterases and their inhibitors; Noradrenergic neuroeffector transmission as a target of drug action; Drugs with noradrenergic prejunctional sites of action; Drugs that modify the release of noradrenaline; Drugs that modify the inactivation of noradrenaline; Agonists at adrenoceptors; Antagonists at adrenoceptors; The adrenal medulla.
- Chapter 3. Drug action on peripheral tissues
- drugs acting on signalling and transduction mechanisms other than those directly related to receptors for neurotransmitters and hormoneshormones; Local anaesthesia; Cardiac antidysrhythmic drugs; Cardiac glycosides; Calcium channel blockers; Methylxanthines; Nitrates; Diuretics; Anticoagulant, antithrombotic and fibrinolytic compounds; Lipid-lowering drugs; Chapter 4. Endocrine pharmacology; Hypothalamo-pituitary axis; Gonadotrophins; Oestrogens, progestogens and androgens; The thyroid gland and drugs used in thyroid abnormalities.
- The adrenal cortex and the corticosteroidsDrugs in diabetes mellitus; Posterior pituitary hormones; Angiotensin; Local hormones; Inflammation; Chapter 5. Drug action on the central nervous system; Chemical transmission in the CNS; Extrapyramidal disorders of movement; Antidepressive drugs; Antipsychotic drugs; Vomiting, emetics and antiemetics; Opioid analgesics and their antagonists; Stimulants and hallucinogens; Antipyretic analgesics; The state of consciousness and the general anaesthetic agents; Chapter 6. Antiparasitic chemotherapy; Biochemical selectivity; Distributional selectivity.