The New genetics of mental illness /

The New Genetics of Mental Illness is a collection of papers that discusses the advancement of molecular biology in the context of psychiatry. The book presents papers that are organized thematically. The text first discusses the basics of biology and quantitative models, and then proceeds to coveri...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor Corporativo: Mental Health Foundation (London, England)
Otros Autores: McGuffin, P. (Peter), Murray, Robin M., 1944-
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Oxford : [London] : Butterworth-Heinemann ; Mental Health Foundation, 1991.
Temas:
Mental illness > Genetic aspects.
Mental Disorders > genetics
Maladies mentales > Aspect g�en�etique.
HEALTH & FITNESS > Diseases > General.
MEDICAL > Clinical Medicine.
MEDICAL > Diseases.
MEDICAL > Evidence-Based Medicine.
MEDICAL > Internal Medicine.
Mental illness > Genetic aspects
Psychische St�orung
Genetik
Aufsatzsammlung
Psychische stoornissen.
Genetica.
Humans > Mental disorders > Genetics
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Front Cover; The New Genetics of Mental Illness; Copyright Page; Table of Contents; Contributors; Preface; Chapter 1. The cell, molecular biology and the new genetics; THE STRUCTURE AND FUNCTION OF CHROMOSOMES; GENETICS AND THE MOLECULAR BASIS OF HEREDITY; THE NEW GENETICS; THE APPLICATION OF MOLECULAR GENETICS TO THE STUDY OF DISEASE; THE STUDY OF GENE EXPRESSION; CONCLUSIONS; REFERENCES; Chapter 2. Genetic models of madness; SIMPLE GENETIC MODELS AND IRREGULAR TRAITS; MULTIFACTORIAL MODELS; ITERATIVE MODEL FITTING; SEGREGATION ANALYSIS; THE BENEFITS AND LIMITATIONS OF QUANTITATIVE MODELS
  • THE LIMITATIONS OF OPERATIONAL CRITERIAA POLYDIAGNOSTIC APPROACH TO THE CLASSIFICATION OF PSYCHOTIC ILLNESS; CONCLUSIONS; REFERENCES; Chapter 6. Schizophrenia: Classical approaches with new twists and provocative results; HISTORICAL DEMOGRAPHY AND CONTEMPORARY EPIDEMIOLOGY; FAMILIAR FAMILIAL RISKS AS CLUES TO MODE OF TRANSMISSION; UNEXPRESSED GENOTYPES, PATHOPLASTIC PHENOTYPES, AND COMPLEXITY; CONCLUSIONS; REFERENCES; Chapter 7. Genetic linkage studies of schizophrenia; INTRODUCTION; GENETICS AND SCHIZOPHRENIA; CONCLUSIONS; ACKNOWLEDGEMENTS; REFERENCES
  • Chapter 8. Aberrant neurodevelopment as the expression of the schizophrenia genotypeNEURO-IMAGING STUDIES; EARLY DEVELOPMENTAL FACTORS; NEURODEVELOPMENT AND NEUROPATHOLOGY; GENETIC SPECIFICATION OF NEURODEVELOPMENT; CONCLUSION; ACKNOWLEDGEMENTS; REFERENCES; Cha[pter 9. The familial aggregation of affective disorders: relation to symptom severity and social provocation; CASE DEFINITION AS A PREREQUISITE OF GENETIC EPIDEMIOLOGY; EPIDEMIOLOGICAL PITFALLS IN GENETIC RESEARCH; STRATEGIC APPROACHES TO THE GENETICS OF AFFECTIVE DISORDERS; THE CAMBERWELL DEPRESSION STUDY; REFERENCES
  • Chapter 10. Life events and depressive symptoms: a twin study perspectiveINTRODUCTION; METHODS; RESULTS; DISCUSSION; ACKNOWLEDGEMENTS; REFERENCES; Chapter 11. Genetic markers and affective disorder; THE EVIDENCE FOR GENETIC INFLUENCES; MODE OF INHERITANCE; GENETIC MARKERS; CONCLUSIONS AND FUTURE PROSPECTS; REFERENCES; Chapter 12. The genetics of vulnerability to alcoholism; CLASSICAL GENETIC STUDIES; HIGH RISK STUDIES; ALCOHOL CHALLENGE STUDIES IN TWINS; GENETIC MARKERS; ALCOHOL-METABOLIZING ENZYMES; MAPPING ALCOHOL-RELATED BEHAVIOURAL TRAITS IN MICE; CONCLUSIONS; REFERENCES

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