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Signal transduction /

Up-to-date, inclusive coverage of targeting transduction pathways for research and medical intervention * In-depth coverage of nuclear receptors, including steps in isolation of steriod hormones and the discovery of intracellular hormone receptors; Tyrosine protein kinases and adaptive immunity; and...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Gomperts, B. D.
Otros Autores: Tatham, Peter E. R. (Life scientist), Kramer, Ijsbrand M.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam ; Boston : Elsevier/Academic Press, �2009.
Edición:2nd ed.
Temas:
Acceso en línea:Texto completo
Texto completo

MARC

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100 1 |a Gomperts, B. D. 
245 1 0 |a Signal transduction /  |c Bastien D. Gomperts, Ijsbrand M. Kramer, Peter E.R. Tatham. 
250 |a 2nd ed. 
260 |a Amsterdam ;  |a Boston :  |b Elsevier/Academic Press,  |c �2009. 
300 |a 1 online resource (xxvii, 810 pages) :  |b color illustrations 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
520 |a Up-to-date, inclusive coverage of targeting transduction pathways for research and medical intervention * In-depth coverage of nuclear receptors, including steps in isolation of steriod hormones and the discovery of intracellular hormone receptors; Tyrosine protein kinases and adaptive immunity; and intracellular calcium * Extensive conceptual colour artwork to assist with comprehension of key topics * Instrumental margin notes highlight milestones in signalling mechanisms DESCRIPTION: Signal Transduction is a thorough, well-illustrated study in cellular signaling processes. Beginning with the basics, this book shows how cells respond to external cues, hormones, growth factors, cytokines, cell surfaces, etc., and further instructs how these inputs are integrated. Instruction continues with up-to-date, inclusive coverage of intracellular calcium, nuclear receptors, tyrosine protein kinases and adaptive immunity, and targeting transduction pathways for research and medical intervention. Signal Transduction serves as an invaluable resource for advanced undergraduates, graduate researchers, and established scientists working in cell biology, pharmacology, immunology, and related fields. 
504 |a Includes bibliographical references and index. 
505 0 |a Prologue: Signal Transduction, origins and ancestors -- First messengers -- Receptors -- GTP-binding proteins and signal transduction -- Effector enzymes coupled to GTP binding proteins: adenylyl cyclase and phospholipase C -- The regulation of visual transduction and olfaction -- Intracellular calcium -- Calcium effectors -- Phosphorylation and dephosphorylation: protein kinases A and C -- Nuclear receptors -- Growth Factors: Setting the framework -- Signalling pathways operated by receptor protein tyrosine kinases -- Signal transduction to and from adhesion molecules -- Adhesion molecules in the regulation of cell differentiation: Mainly about Wnt -- Activation of the innate immune system: the Toll-like receptor 4 and Signalling through Ubiquitylation -- Traffic of white blood cells -- Tyrosine protein kinases and adaptive immunity : TCR, BCR, soluble tyrosine kinases and NFAT -- Phosphoinositide 3-kinases, protein kinase B and signalling through the insulin receptor -- Protein Kinase C revisited -- Signalling through receptor serine/threonine kinases -- Protein dephosphorylation and protein phosphorylation -- Notch -- Targeting transduction pathways for research and medical intervention -- Protein domains and signal transduction. 
588 0 |a Print version record. 
650 0 |a Cellular signal transduction. 
650 2 |a Signal Transduction  |0 (DNLM)D015398 
650 6 |a Transduction du signal cellulaire.  |0 (CaQQLa)201-0206812 
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650 7 |a Cellular signal transduction  |2 fast  |0 (OCoLC)fst00850288 
650 1 7 |a Transduction du signal.  |2 fmesh 
650 7 |a Signaltransduktion  |2 gnd  |0 (DE-588)4318717-1 
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650 7 |a Transduction du signal cellulaire.  |2 ram 
653 0 0 |a signaaltransductie 
653 0 0 |a signal transduction 
653 1 0 |a Cellular Biology 
653 1 0 |a Celbiologie 
655 4 |a Internet Resources. 
700 1 |a Tatham, Peter E. R.  |c (Life scientist) 
700 1 |a Kramer, Ijsbrand M. 
776 0 8 |i Print version:  |a Gomperts, B.D.  |t Signal transduction.  |b 2nd ed.  |d Amsterdam ; Boston : Elsevier/Academic Press, �2009  |z 9780123694416  |z 0123694418  |w (OCoLC)373478545 
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