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Anandamide an Endogenous Cannabinoid /
First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms. Under the capable and qualified editorial l...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
Amsterdam ; Boston :
Elsevier/Academic Press,
2009.
|
| Edición: | First edition. |
| Colección: | Vitamins and hormones ;
v. 81. |
| Temas: | |
| Acceso en línea: | Texto completo Texto completo |
MARC
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| 245 | 0 | 0 | |a Anandamide an Endogenous Cannabinoid / |c Gerald Litwack. |
| 250 | |a First edition. | ||
| 264 | 1 | |a Amsterdam ; |a Boston : |b Elsevier/Academic Press, |c 2009. | |
| 300 | |a 1 online resource (xxii, 513 pages) : |b illustrations | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 490 | 1 | |a Vitamins and hormones, |x 0083-6729 ; |v v. 81 | |
| 546 | |a Text in English. | ||
| 504 | |a Includes bibliographical references and index. | ||
| 588 | 0 | |a Print version record. | |
| 520 | |a First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms. Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists, and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and vitamins will, as always, turn to this series for comprehensive reviews by leading contributors to this and related disciplines. This volume reviews recent advances in the formation of endogenous cannabinoids, their receptors, metabolism and relation to disease processes. *Longest running series published by Academic Press *Contributions by leading international authorities. | ||
| 505 | 0 | |a Front Cover ; Vitamins and Hormones ; Copyright Page ; Contents ; Contributors ; Preface ; Chapter 1: Enzymatic Formation of Anandamide ; I. The Transacylation-Phosphodiesterase Pathway for Anandamide Formation ; II. NAT ; A. Ca-NAT ; B. iNAT ; III. NAPE-PLD; A. Structure; B. Function; C. Tissue distribution ; IV. Alternative Pathways Forming NAEs from NAPEs ; V. Conclusions; References ; Chapter 2: Organized Trafficking of Anandamide and Related Lipids; I. AEA and the Endocannabinoid System ; A. Discovery of endocannabinoids; B. AEA synthesis ; C. AEA signaling ; D. AEA degradation. | |
| 505 | 8 | |a E. Lipid rafts and the fate of AEA metabolites II. AEA Transport ; A. Fatty acid transporters ; B. Lipid transfer proteins ; C. Characteristics of AEA transport ; D. Proposed models for cellular AEA accumulation ; E. Implications of pharmacologically altered AEA signaling ; Acknowledgment ; References; Chapter 3: Biosynthesis of Oleamide ; I. Introduction ; II. Fatty Acid Amide Messengers: Structural Considerations ; III. Natural Occurrence of Oleamide ; IV. Biologic Actions of Oleamide ; V. Proposed Mechanisms for the Biosynthesis of Oleamide. | |
| 505 | 8 | |a VI. Oleamide Biosynthesis by Peptidylglycine Alpha-amidating Monooxygenase VII. Discovery of Cytochrome c as an Oleamide Synthase ; VIII. Cytochrome c also Catalyzes the Formation of Oleoylglycine and Other Long-Chain Fatty Acylamino Acids ; IX. Proposal for an Oleamide Synthesome ; X. Apoptosis: A Model for the Mechanism and Regulation of Oleamide Biosynthesis ; XI. Considerations for the Investigation of Oleamide Biosynthesis ; XII. Future Directions and Concluding Remarks ; References; Chapter 4: Anandamide Receptor Signal Transduction ; I. Introduction ; II. Cannabinoid Receptor 1. | |
| 505 | 8 | |a A. Regulation of cyclic AMP B. Nuclear signaling pathways ; C. CB1 Receptor-mediated regulation of ion channels ; 1. Calcium channels ; 2. Potassium channels ; 3. Neuronal plasticity ; III. Cannabinoid Receptor 2 ; A. Signaling pathways ; IV. Transient Receptor Potential Vanilloid 1 ; A. In the nervous system ; B. In vasodilation and bronchoconstriction ; V. Evidence for Additional Receptors ; A. Direct activation of ion channels ; 1. Voltage-gated Ca2+ channels ; 2. Voltage-gated sodium channels ; 3. Voltage-gated potassium channels ; 4. Task-1 ; B. 5-HT3A receptors. | |
| 505 | 8 | |a C. Nicotinic acetylcholine receptors D. Glycine receptors ; E. NMDA receptors ; F. Peroxisome proliferator-activated receptors ; G. Other GPCRs ; VI. Concluding Remarks ; References; Chapter 5: Is GPR55 an Anandamide Receptor? ; I. Delta9-Tetrahydrocannabinol, CB1, and CB2 Receptors ; II. Functional Evidence for Novel Cannabinoid Receptors ; III. Genomics of G Protein-Coupled Cannabinoid Receptors ; IV. The Orphan Receptor GPR55 ; A. Patent reports ; B. Pharmacology of GPR55 ; V. Endogenous Ligands for GPR55 ; A. Lysophosphatidylinositol ; B. LPI as a signaling molecule. | |
| 650 | 0 | |a Cannabinoids. | |
| 650 | 1 | 2 | |a Endocannabinoids |0 (DNLM)D063388 |
| 650 | 2 | |a Cannabinoids |0 (DNLM)D002186 | |
| 650 | 2 | 2 | |a Arachidonic Acids |0 (DNLM)D001095 |
| 650 | 2 | 2 | |a Polyunsaturated Alkamides |0 (DNLM)D053284 |
| 650 | 2 | 2 | |a Receptors, Cannabinoid |0 (DNLM)D043882 |
| 650 | 6 | |a Cannabino�ides. |0 (CaQQLa)201-0078335 | |
| 650 | 6 | |a Endocannabino�ides. |0 (CaQQLa)000278040 | |
| 650 | 7 | |a MEDICAL |x Pain Medicine. |2 bisacsh | |
| 650 | 7 | |a MEDICAL |x Psychiatry |x Psychopharmacology. |2 bisacsh | |
| 650 | 7 | |a Cannabinoids. |2 fast |0 (OCoLC)fst00845733 | |
| 700 | 1 | |a Litwack, Gerald, |e editor. | |
| 776 | 0 | 8 | |i Print version: |t Anandamide an endogenous cannabinoid. |b 1st ed. |d Amsterdam ; Boston : Elsevier/Academic Press, 2009 |z 9780123747822 |w (OCoLC)352568001 |
| 830 | 0 | |a Vitamins and hormones ; |v v. 81. | |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780123747822 |z Texto completo |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/bookseries/00836729/81 |z Texto completo |