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Physiology and pathology of chloride transporters and channels in the nervous system : from molecules to diseases /

The importance of chloride ions in cell physiology has not been fully recognized until recently, in spite of the fact that chloride (Cl- ), together with bicarbonate, is the most abundant free anion in animal cells, and performs or determines fundamental biological functions in all tissues. For many...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Alvarez-Leefmans, F. J. (Francisco J.), Delpire, Eric
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam ; Boston ; London : Elsevier/Academic, 2009.
Edición:1st ed.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Section I Overview of chloride transporters and channels
  • 1. Chloride Channels: An Historical Perspective by H. Criss Hartzell
  • 2. Sodium-Coupled Chloride Cotransporters: Discovery and Newly Emerging Concepts by John Russell
  • 3. Pathophysiology of the K+-Cl- Cotransporters: Paths to Discovery and Overview by John S. Gibson, J. Clive Ellory, Norma C. Adragna and Peter K. Lauf
  • 4. From Cloning to Structure, Function, and Regulation of Chloride-dependent and Independent Bicarbonate Transporters by Michael F.�Romero, Min-Hwang Chang and�David Mount
  • 5. Thermodynamics and Kinetics of chloride transport in Neurons: An Outline by F. Javier Alvarez-Leefmans and Eric Delpire
  • Section II Current methods for studying chloride regulation
  • 6. Chemical and GFP-based Fluorescent Chloride Indicators by Alan S. Verkman
  • 7. Clomeleon, a Genetically-encoded Chloride Indicator by Ken Berglund, Thomas Kuner and George J. Augustine
  • 8. Gramicidin Perforated Patch by Norio Akaike
  • 9. Measuring Electroneutral Chloride-dependent Ion Fluxes in Heterologous Expression Systems by Kenneth
  • Gagnon
  • 10. Knockout models of cation chloride cotransporters by Nicole Garbarini and Eric Delpire
  • Section III From cloning to structure, function and regulation of chloride channels
  • 11. The NKCC and NCC genes: An in silico view by Mauricio Di Fulvio and F. Javier Alvarez-Leefmans
  • 12. The ClC Family of Chloride Channels and Transporters by Tobias Stauber, Gaia Novarino and Thomas J. Jentsch
  • 13. Calcium-Activated Chloride Channels by Fiona Britton, Normand Leblanc and James L. Kenyon
  • 14. GABAA Receptor Channels by Robert L. Macdonald and Emmanuel J. Botzolakis
  • 15. The Puzzles of Volume-Activated Anion Channels by Yasunobu Okada, Kaori Sato, Abduqodir H. Toychiev, Makoto Suzuki, Amal K. Dutta, Hana Inoue and Ravshan Z. Sabirov
  • 16. The Sodium-Dependent Chloride Cotransporters by Gerardo Gamba
  • 17. The Potassium-Chloride Cotransporters: from Cloning to Structure and Function by John A.�Payne
  • 18. Regulation of Cation-Chloride Cotransporters by Gerardo Gamba, Nicole Garbarini and Eric Delpire
  • Section IV Cation-chloride cotransporters in neural function and dysfunction
  • 19. GABA, Glycine and Cation-Chloride Cotransporterts in Retinal Function and Development by Noga Vardi and ling-Li Zhang
  • 20. Chloride-based Signal Amplification in Olfactory Sensory Neurons by Stephan Frings
  • 21. Cochlear and Vestibular Function and Dysfunction by Daniel C. Marcus and Philine Wangemann
  • 22. Presynaptic inhibition, pain and neurogenic inflammation by F. Javier Alvarez-Leefmans
  • 23. Modulation of Chloride Homeostasis by Microglia by Yves De Koninck
  • 24. Cation-Chloride Cotransporters as Pharmacological Targets in the Treatment of Epilepsy by Kristopher T. Kahle and Kevin Staley
  • 25. The Role of Cation-Chloride Cotransporters in Brain Ischemia by Dandan Sun, Doug Kintner and Brooks B. Pond
  • 26. Chloride Transport in Glioma Growth and Cell Invasion by Harald Sontheimer
  • 27. The Sodium-Potassium-Chloride Cotransporter, Human Cytomegalovirus, and the Cell Cycle by John M.�Russell
  • Section V Cation-chloride cotransport in Choroid Plexus and blood brain barrier
  • 28. Chloride Transporters as Water Pumps: Elements in a New Model of Epithelial Water Transport by Nanna MacAulay, Steffen Hamann, and Thomas Zeuthen
  • 29. Choroid plexus and chloride transport by Peter D. Brown, Sarah L. Davies and Ian D. Millar
  • 30. Ion and Water Transport Across the Blood-Brain Barrier by Martha E. O'Donnell.