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Systems biomedicine : concepts and perspectives /
Systems biology is a critical emerging field that seeks to define the interactions of all biological components by examining underlying biochemical and genetic processes. It is a discipline that quantifies and annotates the complexity of biological systems in order to construct algorithmic models to...
| Clasificación: | Libro Electrónico |
|---|---|
| Otros Autores: | , |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
London :
Academic,
2009.
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| Temas: | |
| Acceso en línea: | Texto completo |
MARC
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| 001 | SCIDIR_ocn460116179 | ||
| 003 | OCoLC | ||
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| 008 | 091027s2009 enk o 000 0 eng d | ||
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| 019 | |a 1229185710 | ||
| 020 | |a 9780123725509 | ||
| 020 | |a 012372550X | ||
| 020 | |a 9780080919836 |q (online) | ||
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| 035 | |a (OCoLC)460116179 |z (OCoLC)1229185710 | ||
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| 060 | 4 | |a QU 26.5 S995 2009 | |
| 082 | 0 | 4 | |a 610.113 |2 22 |
| 245 | 0 | 0 | |a Systems biomedicine : |b concepts and perspectives / |c edited by Edison T. Liu, Douglas A. Lauffenburger. |
| 260 | |a London : |b Academic, |c 2009. | ||
| 300 | |a 1 online resource | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a computer |b c |2 rdamedia | ||
| 338 | |a online resource |b cr |2 rdacarrier | ||
| 520 | |a Systems biology is a critical emerging field that seeks to define the interactions of all biological components by examining underlying biochemical and genetic processes. It is a discipline that quantifies and annotates the complexity of biological systems in order to construct algorithmic models to predict outcomes from component input. Applications in medicine are revolutionizing our understanding of biological processes and systems. Systems Biomedicine is organized around foundations, computational modelling, network biology, and integrative biology, with the extension of examples from human biology and pharmacology, to focus on the applications of systems approaches to medical problems. An integrative approach to the underlying genomic, proteomic, and computational biology principles provides researchers with guidance in the use of qualitative systems and hypothesis generators. To reflect the highly interdisciplinary nature of the field, careful detail has been extended to ensure explanations of complex mathematical and biological principles are clear with minimum technical jargon. | ||
| 505 | 0 | |a I. Foundations of Systems Biology -- Genomic Technologies for Systems Biology -- Proteomic Technologies -- II. Computational Modeling of Biological Systems -- Dynamic Systems Analysis -- Spatio-temoral Modeling of Cellular Systems -- High-level modeling of biological networks -- High-Performance Computing -- Modeling Software -- III. Network Biology -- Protein Interaction Networks -- Signaling Networks with Modeling Strategies -- Protein networks in integrin-mediated adhesions -- Network Imaging -- RNAi networks -- IV. Integrative Biology of Higher Biosystems -- Signal Processing and Integration During Development -- Systems Biology and Stem Cell Biology -- Application of immunologic modeling in drug discovery and development -- V. Systems Medicine Applications -- Systems Pharmacology. | |
| 588 | 0 | |a Print version record. | |
| 650 | 0 | |a Systems biology. | |
| 650 | 0 | |a Medical sciences |x Computer simulation. | |
| 650 | 0 | |a Digital computer simulation. | |
| 650 | 0 | |a Computer simulation. | |
| 650 | 2 | |a Systems Biology |0 (DNLM)D049490 | |
| 650 | 2 | |a Computer Simulation |0 (DNLM)D003198 | |
| 650 | 6 | |a Biologie syst�emique. |0 (CaQQLa)000260964 | |
| 650 | 6 | |a Sciences de la sant�e |0 (CaQQLa)201-0000875 |x Simulation par ordinateur. |0 (CaQQLa)201-0379159 | |
| 650 | 6 | |a Simulation par ordinateur. |0 (CaQQLa)201-0016791 | |
| 650 | 7 | |a simulation. |2 aat |0 (CStmoGRI)aat300237969 | |
| 650 | 7 | |a Digital computer simulation. |2 fast |0 (OCoLC)fst00893651 | |
| 650 | 7 | |a Computer simulation. |2 fast |0 (OCoLC)fst00872518 | |
| 650 | 7 | |a Medical sciences |x Computer simulation. |2 fast |0 (OCoLC)fst01014604 | |
| 650 | 7 | |a Systems biology. |2 fast |0 (OCoLC)fst01745552 | |
| 650 | 7 | |a Biomathematik |2 gnd |0 (DE-588)4139408-2 | |
| 650 | 7 | |a Medizin |2 gnd |0 (DE-588)4038243-6 | |
| 650 | 7 | |a Systembiologie |2 gnd |0 (DE-588)4809615-5 | |
| 700 | 1 | |a Liu, Edison T. | |
| 700 | 1 | |a Lauffenburger, Douglas A. | |
| 776 | 0 | 8 | |i Print version: |t Systems biomedicine. |d London : Academic, 2009 |z 9780123725509 |z 012372550X |w (OCoLC)432405781 |
| 856 | 4 | 0 | |u https://sciencedirect.uam.elogim.com/science/book/9780123725509 |z Texto completo |