Macromolecular crystallography. Part C /

Accurate molecular structures are vital for rational drug design and for structure-based functional studies directed toward the development of effective therapeutic agents and drugs. Crystallography can reliably predict structure, both in terms of folding and atomic details of bonding. * Methodologi...

Descripción completa

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Carter, Charles W., Sweet, Robert M.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam ; Oxford : Elsevier Academic Press, [2003].
Colección:Methods in enzymology ; v. 368.
Temas:
X-ray crystallography.
Enzymes > Analysis.
Proteins > Analysis.
Crystallography [MESH]
Macromolecular Substances [MESH]
Crystallography, X-Ray
Radiocristallographie.
Enzymes > Analyse.
Prot�eines > Analyse.
Enzymes > Analysis
Proteins > Analysis
X-ray crystallography
Acceso en línea:Texto completo
Texto completo
Tabla de Contenidos:
  • Cover
  • Table of Contents
  • Contributor to Volume 368
  • Preface
  • Volumes in Series
  • Section I: Reminiscences on Methods
  • Chapter 1. Transformations in Structural Biology: Personal View
  • Chapter 2. Origins
  • Chapter 3. Personal X-ray Reflections
  • Section II: Crystals
  • Chapter 4. Robotics for Automated Crystal Formation and Analysis
  • Chapter 5. Use of Limited Proteolysis to Identify Protein Domains Suitable for Structural Analysis
  • Chapter 6. Solvent Entropy Effects in the Formation of Protein Solid Phases
  • Chapter 7. Controlling Biomolecular Crystallization by Understanding the Distinct Effects of PEGs and Salts on Solubility
  • Chapter 8. Counter-diffusion Methods for Macromolecular Crystallization
  • Chapter 9. Growth Sectors and Crystal Quality
  • Chapter 10. Molecular Mechanisms of Defect Formation
  • Chapter 11. Cryocooling of Macromolecular Crystals: Optimization Methods
  • Chapter 12. The Well-Tempered Protein Crystal:Annealing Macromolecular Crystals
  • Section III: Data
  • Chapter 13. What Can I Have As a Source of X-Ray Synchrotron Radiation? A Primer for Potential Users
  • Chapter 14. Protein Crystal Structure Analysis from High- Resolution X-Ray Powder-Diffraction Data
  • Chapter 15. Macromolecular Crystal Quality
  • Chapter 16. Protein Structures at Atomic Resolution
  • Author Index
  • Subject Index
  • Color Plates Section
  • Last Page.

Ejemplares similares