Cargando…

Advances in immunology. Volume 91 /

Advances in Immunology, a long established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecul...

Descripción completa

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Alt, Frederick W.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: San Diego, CA : Elsevier Science & Technology, 2006.
Colección:Advances in immunology.
Temas:
Acceso en línea:Texto completo
Texto completo

MARC

LEADER 00000cam a2200000Mi 4500
001 SCIDIR_ocn441763585
003 OCoLC
005 20231117032832.0
006 m o d
007 cr zn|||||||||
008 070816s2006 cauaf ob 001 0 eng d
040 |a MERUC  |b eng  |e pn  |c MERUC  |d OCLCQ  |d IDEBK  |d OPELS  |d OCLCQ  |d OCLCF  |d OCLCQ  |d EBLCP  |d OCLCQ  |d ESU  |d OCLCQ  |d MERUC  |d D6H  |d OCLCQ  |d LEAUB  |d OCLCQ  |d OCLCO  |d OCLCQ  |d OCLCO 
019 |a 935923120 
020 |a 0080464513  |q (electronic bk.) 
020 |a 9780080464510  |q (electronic bk.) 
020 |a 0120224917  |q (electronic bk.) 
020 |a 9780120224913  |q (electronic bk.) 
035 |a (OCoLC)441763585  |z (OCoLC)935923120 
050 4 |a QR180  |b .A38 2006eb 
082 0 4 |a 571.9/6  |2 23 
245 0 0 |a Advances in immunology.  |n Volume 91 /  |c edited by Frederick W. Alt. 
260 |a San Diego, CA :  |b Elsevier Science & Technology,  |c 2006. 
300 |a 1 online resource (x, 285 pages, 8 leaves of plates) :  |b illustrations 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
490 1 |a Advances in Immunology ;  |v v. 91 
504 |a Includes bibliographical references and index. 
505 0 |a Cover -- Cover Page -- Title Page -- Copyright Page -- Contents -- Contributors -- Chapter 1: A Reappraisal of Humoral Immunity Based on Mechanisms of Antibody-Mediated Protection Against Intracellular Pathogens -- 1. Introduction -- 2. Intracellular and Extracellular Pathogenic Microbes: How Distinct Are They? -- 3. Components of AMI -- 4. AMI in the Context of the "Damage-Response Framework" -- 5. Abs as Enhancers of Innate Immunity -- 6. Abs as Direct and Indirect Effector Molecules -- 7. AMI as a Regulator of the Inflammatory Response -- 8. Dose-Response Conundrum -- 9. Ab-Mediated Protection Against Intracellular Pathogens -- 10. Protective Efficacy of an Ab Molecule -- 11. Some Emerging Concepts -- Acknowledgments -- References -- Chapter 2: Accessibility Control of V(D)J Recombination -- 1. Introduction -- 2. V(D)J Recombination: A Mechanistic Perspective -- 3. Genomic Architecture of Ig and TCR Loci -- 4. Regulation of Antigen Receptor Gene Assembly During Lymphocyte Development -- 5. Regulation of V(D)J Recombination: The Accessibility Hypothesis and Beyond -- 6. Chromatin Structure and Accessibility Control Mechanisms -- 7. Regulation of Antigen Receptor Loci by Nuclear Topography -- 8. Regulation of Chromatin Accessibility and V(D)J Recombination by Cis-Acting Elements -- 9. Role of Transcription in Accessibility Control of V(D)J Recombination -- 10. Transcription Factors Involved in Accessibility Control of Ig and TCR Loci -- 11. Control of Recombinase Accessibility by Chromatin Modifications and Remodeling -- 12. Concluding Remarks -- Acknowledgments -- References -- Chapter 3: Targeting Integrin Structure and Function in Disease -- 1. Introduction -- 2. Structure, Ligand-Binding Sites, and Competitive Antagonists -- 3. Large Conformational Changes and Affinity States -- 4. I-Domain Allosteric Site and Antagonists -- 5. An Internal Ligand -- 6. betaI-Domain Allosteric Regulation -- 7. The PSI- and EGF-Domain Restraints -- 8. The Cytoplasmic Domain Restraint -- 9. Therapeutics -- 10. Concluding Remarks -- Acknowledgments -- References -- Chapter 4: Endogenous TLR Ligands and Autoimmunity -- 1. Introduction (Short Overview on TLR Immunobiology) -- 2. The Innate: Adaptive Immune Connection -- 3. TLR-Mediated Immunostimulatory Potential of Self-RNA and -DNA -- 4. Function of IFN-alpha/beta -- 5. Cytokine-Driven DC Activation: A Portal for Autoimmunity? -- 6. TLRs and Autoimmunity -- 7. TLRs and "Innate Autoimmunity" -- Acknowledgments -- References -- Chapter 5: Genetic Analysis of Innate Immunity -- 1. Introduction -- 2. How Do We Detect Infection? -- 3. Forward and Reverse Genetic Analyses of TLR Signaling -- 4. TLR-Independent Detection of Microbes -- 5. Global Resistome -- 6. Endogenous Activators of TLR Signaling? -- 7. Conclusions About Innate Immunity and the Classical Genetic Approach -- Acknowledgments --t. 
588 0 |a Print version record. 
520 |a Advances in Immunology, a long established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research. 
650 0 |a Immunology. 
650 2 |a Allergy and Immunology  |0 (DNLM)D000486 
650 6 |a Immunologie.  |0 (CaQQLa)201-0066630 
650 7 |a Immunology  |2 fast  |0 (OCoLC)fst00968006 
700 1 |a Alt, Frederick W. 
776 0 8 |i Print version:  |a Alt, Frederick W.  |t Advances in Immunology.  |d London : Elsevier Science, �2006  |z 9780120224913 
830 0 |a Advances in immunology. 
856 4 0 |u https://sciencedirect.uam.elogim.com/science/book/9780120224913  |z Texto completo 
856 4 0 |u https://sciencedirect.uam.elogim.com/science/bookseries/00652776/91  |z Texto completo