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Palladium in heterocyclic chemistry : a guide for the synthetic chemist /

Palladium chemistry, despite its immaturity, has rapidly become an indispensable tool for synthetic organic chemists. Heterocycles are of paramount importance in the pharmaceutical industry and palladium chemistry is one of the most novel and efficient ways of making heterocycles. Today, palladium-c...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Autor principal: Li, Jie Jack
Otros Autores: Gribble, Gordon W.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam ; Boston : Elsevier, 2006.
Edición:2nd ed.
Colección:Tetrahedron organic chemistry series ; v. 26.
Temas:
Acceso en línea:Texto completo
Texto completo
Tabla de Contenidos:
  • Cover
  • Front cover
  • Contents
  • Preface to the second edition
  • Preface to the first edition
  • Abbreviations
  • Chapter 1 An introduction to palladium catalysis
  • 1.1 Oxidative coupling/cyclization
  • 1.2 Cross-coupling reactions with organometallic reagents
  • 1.3 The Sonogashira reaction
  • 1.4 The Heck, intramolecular Heck, and heteroaryl Heck reactions
  • 1.5 Carbonylation reactions
  • 1.6 The Pd-catalyzed C-P bond formation
  • 1.7 Palladium-catalyzed C-N bond and C-O bond-forming reactions
  • 1.8 The Tsuji-Trost reaction
  • 1.9 The Wacker-type reactions
  • 1.10 Mori-Ban, Hegedus, and Larock indole syntheses
  • 1.11 References
  • Chapter 2 Pyrroles
  • 2.1 Synthesis of pyrrolyl halides
  • 2.2 Oxidative coupling/cyclization
  • 2.3 Coupling reactions with organometallic reagents
  • 2.4 Sonogashira reaction
  • 2.5 Heck and intramolecular Heck reactions
  • 2.6 Carbonylation
  • 2.7 C-N bond formation reactions
  • 2.8 Miscellaneous
  • 2.9 References
  • Chapter 3 Indoles
  • 3.1 Synthesis of indolyl halides
  • 3.2 Oxidative coupling/cyclization
  • 3.3 Coupling reactions with organometallic reagents
  • 3.4 The Sonogashira coupling
  • 3.5 Heck couplings
  • 3.6 Carbonylation
  • 3.7 C-N bond formation reactions
  • 3.8 Miscellaneous
  • 3.9 References
  • Chapter 4 Pyridines
  • 4.1 Synthesis of halopyridines
  • 4.2 Coupling reactions with organometallic reagents
  • 4.3 Sonogashira reaction
  • 4.4 Heck and intramolecular Heck reactions
  • 4.5 Buchwald-Hartwig aminations(C-N bond formation)
  • 4.6 Direct C-C bond formation
  • 4.7 Summary
  • 4.8 References
  • Chapter 5 Thiophenes and benzo[b]thiophenes
  • 5.1 Preparation of halothiophenes and halobenzothiophenes
  • 5.2 Oxidative and reductive coupling reactions
  • 5.3 Cross-coupling with organometallic reagents
  • 5.4 Sonogashira reaction
  • 5.5 Heck and intramolecular Heck reactions
  • 5.6 Carbonylation reactions
  • 5.7 Buchwald-Hartwig aminations
  • 5.8 Miscellaneous
  • 5.9 References
  • Chapter 6 Furans and benzo[b]furans
  • 6.1 Synthesis of halofurans and halobenzo[b]furans
  • 6.2 Oxidative coupling/cyclization
  • 6.3 Coupling reactions with organometallic reagents
  • 6.4 Sonogashira reaction
  • 6.5 Heck, intramolecular Heck, and heteroaryl Heck reactions
  • 6.6 Heteroannulation
  • 6.7 Carbonylation and C-N and C-O bond formation
  • 6.8 References
  • Chapter 7 Thiazoles and benzothiazoles
  • 7.1 Synthesis of halothiazoles
  • 7.2 Coupling reactions with organometallic reagents
  • 7.3 Sonogashira reaction
  • 7.4 Heck and heteroaryl Heck reactions
  • 7.5 Carbonylation
  • 7.6 C-N bond formation
  • 7.7 Site selective coupling reactions
  • 7.8 References
  • Chapter 8 Oxazoles and benzoxazoles
  • 8.1 Introduction
  • 8.2 Synthesis of halooxazoles and halobenzoxazoles
  • 8.3 Coupling reactions with organometallic reagents
  • 8.4 Heck and heteroaryl Heck reactions
  • 8.5 Carbonylation
  • 8.6 Palladium-catalyzed amination
  • 8.7 Carbopalladation of nitriles
  • 8.8 Quaterfuran and Quinquifuran
  • 8&#4.