Complex enzymes in microbial natural product biosynthesis. Part B, Polyketides, aminocoumarins, and carbohydrates /

This volume will showcase the most important chemical classes of complex enzymes, which have been an important traditional source of valuable antibiotics and other drugs.

Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Hopwood, D. A.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam ; Boston : Elsevier/Academic Press, 2009.
Edición:1st ed.
Colección:Methods in enzymology ; v. 459.
Temas:
Biosynthesis.
Polyketides > Synthesis.
Peptides > Synthesis.
Carbohydrates > Synthesis.
Biological Products > biosynthesis
Enzymes > biosynthesis
Carbohydrates > biosynthesis
Peptide Biosynthesis
Polyketide Synthases > biosynthesis
Biosynth�ese.
Ac�etog�enines > Synth�ese.
Peptides > Synth�ese.
Glucides > Synth�ese.
SCIENCE > Life Sciences > Biochemistry.
natuurlijke producten
natural products
biosynthese
biosynthesis
acetogeninen
acetogenins
cumarinen
coumarins
Biochemistry
Biochemie
Acceso en línea:Texto completo
Texto completo
Tabla de Contenidos:
  • Introduction to polyketide biosynthesis / K.J. Weissman
  • Structural enzymology of polyketide synthases / S.C. Tsai and B.D. Ames
  • Fungal type I polyketide synthases / R.J. Cox and T.J. Simpson
  • Tandem acyl carrier protein domains in polyunsaturated fatty acid synthases / H. Jiang, S.R. Rajski and B. Shen
  • Iterative type I polyketide synthases for enediyne core biosynthesis / G.P. Horsman, S.G. Van Lanen and B. Shen
  • The DEBS paradigm for type I modular polyketide synthases and beyond / L. Katz
  • Formation and characterization of acyl carrier protein-linked polyketide synthase extender units / Y.A. Chan and M.G. Thomas
  • Type I polyketide synthases that require discrete acyltransferases / Y.Q. Cheng [and others]
  • The enzymology of polyether biosynthesis / T. Liu, D.E. Cane and Z. Deng
  • Enzymology of the polyenes pimaricin and candicidin biosynthesis / J.F. Martin and J.F. Aparicio
  • Genetic analysis of nystatin and amphotericin biosynthesis / S. Zotchev and P. Caffrey
  • Polyketide versatility in the biosynthesis of complex mycobacterial cell wall lipids / T. Chopra and R.S. Gokhale
  • Genetic engineering to produce polyketide analogues / C.D. Reeves and E. Rodriguez
  • Design and synthesis of pathway genes for polyketide biosynthesis / S. Peiru, H. Gramajo and H.G. Menzella
  • Heterologous production of polyketides in bacteria / E. Rodriguez, H.G. Menzella and H. Gramajo
  • In vitro analysis of type II polyketide synthase / W. Zhang and Y. Tang
  • Bacterial fatty acid synthesis and its relationships with polyketide synthetic pathways / J.E. Cronan and J. Thomas
  • Aminocoumarins mutasynthesis, chemoenzymatic synthesis, and metabolic engineering / L. Heide
  • Enzymology of aminoglycoside biosynthesis-deduction from gene clusters / U.F. Wehmeier and W. Piepersberg
  • Biosynthetic enzymes for the aminoglycosides butirosin and neomycin / F. Kudo and T. Eguchi
  • Enzymatic synthesis of TDP-deoxysugars / J. White-Phillip, C.J. Thibodeaux and H.W. Liu.

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