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Autophagy in mammalian systems. Part B /
Particularly in times of stress, like starvation and disease, higher organisms have an internal mechanism in their cells for chewing up and recycling parts of themselves. The process of internal "house-cleaning" in the cell is called autophagy - literally self-eating. Breakthroughs in unde...
| Clasificación: | Libro Electrónico |
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| Otros Autores: | |
| Formato: | Electrónico eBook |
| Idioma: | Inglés |
| Publicado: |
San Diego, California ; London :
Academic Press/Elsevier,
�2009.
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| Colección: | Methods in enzymology ;
volume 452. |
| Temas: | |
| Acceso en línea: | Texto completo Texto completo Texto completo |
| Sumario: | Particularly in times of stress, like starvation and disease, higher organisms have an internal mechanism in their cells for chewing up and recycling parts of themselves. The process of internal "house-cleaning" in the cell is called autophagy - literally self-eating. Breakthroughs in understanding the molecular basis of autophagy came after the cloning of ATG1 in yeast. These ATG genes in yeast were the stepping stones to the explosion of research into the molecular analysis of autophagy in higher eukaryotes. In the future, this research will help to design clinical approaches that can turn on autophagy and halt tumor growth. In this volume, a robust slate of methods for conducting research are presented, establishing a consensus of appropriate criteria for monitoring autophagy. Along with Autophagy: Lower Eukaryotes, this volume marks the seminal collection of methods in the burgeoning field of autophagy |
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| Notas: | Called Part B in continuation of Part A issued as volume 451 of Methods in enzymology under title: Autophagy : Lower eukaryotes and non-mammalian species, Part A. |
| Descripción Física: | 1 online resource (xlix, 508 pages, 12 unnumbered pages of plates) : illustrations (some color) |
| Bibliografía: | Includes bibliographical references and indexes. |
| ISBN: | 9780080923253 0080923259 9780123745477 0123745470 |
| ISSN: | 0076-6879 ; |