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Transfusion medicine and hemostasis : clinical and laboratory aspects /

This new handbook in transfusion medicine and hemostasis aims to combine clinical and laboratory information from two fields which have high degrees of overlap into one concise, easy-to-use pocket book. This comprehensive reference guide will have the depth of information to be helpful to all physic...

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Detalles Bibliográficos
Clasificación:Libro Electrónico
Otros Autores: Hillyer, Christopher D.
Formato: Electrónico eBook
Idioma:Inglés
Publicado: Amsterdam ; Boston : Elsevier, �2009.
Temas:
Acceso en línea:Texto completo
Tabla de Contenidos:
  • Part I. Blood banding and transfusion medicine
  • Blood banding and transfusion medicine: the field, the discipline and the industry
  • Brief history of blood transfusion
  • Introduction to quality systems and quality management
  • The role of the physician in the blood center-- The blood donor, donation process and technical aspects of blood collection
  • Apheresis blood component collections
  • Recipient-specific blood donations
  • Adverse donor reactions
  • Component preparation and manufacturing
  • Serologic testing of donor products
  • Overview of infectious disease testing
  • HIV screening of donor products
  • Hepatitis B screening of donor products
  • Hepatitis C screening of donor products
  • West Nile virus screening of donor products
  • Syphilis, HTLV and Chagas testing of donor products
  • Bacterial detection methods
  • The role of the transfusion service physician
  • Pretransfusion testing
  • Antibody identification
  • Direct antiglobulin test
  • ABO and H blood group system
  • Rh blood group system
  • Kell and Kidd blood group systems
  • MNS and Duffy blood group systems
  • Lewis I and P blood group systems
  • Other blood group systems, collections and antigens
  • Red blood cells and related products
  • Plasma products
  • Platelet products
  • Cryoprecipitate
  • Granulocyte products
  • Albumin and related products
  • Human immunoglobulin preparations
  • Rh immune globulin
  • Irradiation of blood products
  • Leukoreduction of blood products
  • CMV-safe blood products
  • Frozen blood products
  • Washed blood products
  • Volume-reduced products
  • Neonatal and pediatric transfusion medicine
  • Perinatal transfusion medicine
  • Autoimmune hemolytic anemias
  • Transfusion management in patients with hemoglobinopathies
  • Transfusion of patients undergoing HPC and solid-organ transplantation
  • Transfusion of HIV-positive patients
  • Management of patients who refuse blood transfusion
  • Platelet transfusion refractory patients
  • Massive transfusion
  • Perioperative blood management
  • Adverse events and outcomes following transfusion: an overview
  • Febrile non-hemolytic transfusion reactions
  • Allergic, anaphylactoid and anaphylactic reactions
  • Delayed hemolytic transfusion reactions
  • Transfusion-associated circulatory overload
  • Transfusion-related acute lung injury
  • Septic transfusion reactions
  • Metabolic, hypotensive and other acute reactions and complications
  • Posttransfusion purpura
  • Transfusion associated graft versus host disease
  • Microchimerism
  • Transfusion related immunomodulation
  • Iron overload
  • Transfusion transmitted diseases
  • Overview of therapeutic apheresis
  • Therapeutic plasma exchange
  • Therapeutic erythrocytapheresis
  • Therapeutic thrombocytapheresis
  • Therapeutic leukapheresis
  • Extracorporeal photopheresis
  • LDL pheresis
  • Immunoadsorption
  • Therapeutic phlebotomy
  • HPC products
  • Tissue banking in the hospital setting.
  • Part II. Coagulation
  • Overview of the coagulation system
  • Approach to the bleeding patient
  • Congenital thrombocytopenia
  • Neonatal alloimmune thrombocytopenia
  • Acquired neonatal thrombocytopenia
  • Bernard-Soulier syndrome and other GPIb-IX-V related receptor defects
  • Glanzmann thrombasthenia
  • Platelet storage-granule defects
  • Failure to release and aspirin-like defects
  • Acute (childhood) immune thrombocytopenic purpura
  • Chronic immune thrombocytopenic purpura
  • Drug-induced thrombocytopenia
  • Heparin-induced thrombocytopenia
  • autoimmune lymphoproliferative syndrome
  • Hemolytic uremic syndrome
  • Thrombotic thrombocytopenic purpura
  • Antiphospholipid antibody syndrome
  • von Willebrand disease
  • Hemophilia A
  • Hemophilia B
  • Congenital disorders of fibrinogen
  • Factor XIII, [alpha][2]-antiplasmin and plasminogen activator inhibitor-1 deficiencies
  • Factor XI deficiency
  • Factor VII deficiency
  • Factor II, factor V and factor X deficiencies
  • Bleeding disorders in pregnancy
  • Vascular bleeding disorders
  • Bleedings risks with liver disease
  • Bleeding risks with vitamin K deficiency
  • Bleeding risks with cardiac disease
  • Bleeding risks with renal disease
  • Bleeding risks in cancer
  • Disseminate intravascular coagulopathy
  • Acquired coagulation factor inhibitors
  • Introduction to coagulation testing
  • Prothrombin time and activated partial thromboplastin time
  • Platelet count
  • Global tests of primary hemostasis
  • Platelet aggregation studies
  • Laboratory diagnosis of genetic platelet function defects
  • Laboratory diagnosis of acquired platelet function defects
  • Laboratory diagnosis of immune thrombocytopenic purpura
  • ADAMTS13 testing
  • Laboratory diagnosis of heparin-induced thrombocytopenia
  • Molecular biology of von Willebrand disease
  • Laboratory diagnosis of inherited von Willebrand disease
  • Laboratory diagnosis of acquired von Willebrand syndrome
  • Laboratory assessment of treatment of von Willebrand disease
  • Coagulation factor testing
  • Mixing studies
  • Specific factor inhibitor testing
  • Laboratory diagnosis of dysfibrinogenemia and afibrinogenemia
  • Laboratory assessment of fibrinolysis
  • General overview of the hypercoagulable state
  • Antithrombin testing
  • Proteins C, S and Z testing
  • Activated protein C resistance and factor V Leiden testing
  • Prothrombin gene mutation testing
  • Laboratory diagnosis of hyperhomocysteinemia
  • Laboratory diagnosis of lupus anticoagulant and antiphospholipid antibodies
  • Lipoproteins(a) testing
  • Laboratory diagnosis of factor level abnormalities associated with thrombosis
  • Laboratory management of DIC
  • Laboratory support for heparin monitoring
  • Laboratory support for Warfarin monitoring
  • Prothrombin complex concentrates
  • von Willebrand factor concentrates
  • Factor VIII concentrates
  • Factor IX concentrates
  • Factor VII concentrates
  • Antithrombin concentrates
  • Protein C concentrates.